Persistently culture positive Acanthamoeba keratitis: In vivo resistance and in vitro sensitivity

Ophthalmology

Volumn 110, Issue 8, 2003, Pages 1593-1600

  Pérez Samonja, Juan J ^a,b   Kilvington, Simon ^b   Hughes, Reanne ^b   Tufail, Adnan ^a   Matheson, Melville ^c   Dart, John K G ^a  

^a MOORFIELDS EYE HOSPITAL   (United Kingdom)

^b Medical Sciences Building ^*  (Spain)

^c UNIVERSITY COLLEGE LONDON   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIAMEBIC AGENT; CHLORAMPHENICOL; CHLORHEXIDINE; CYCLOSPORIN A; DEXAMETHASONE; EXOCIN; EYE DROPS; FLURBIPROFEN; HEXAMIDINE ISETIONATE; IMMUNOSUPPRESSIVE AGENT; MYCOPHENOLIC ACID 2 MORPHOLINOETHYL ESTER; NONSTEROID ANTIINFLAMMATORY AGENT; OFLOXACIN; POLY(HEXAMETHYLENEBIGUANIDE); PREDNISOLONE; PROPAMIDINE ISETHIONATE;

ACANTHAMOEBA KERATITIS; ADULT; CLINICAL ARTICLE; CLINICAL FEATURE; CORNEA PERFORATION; CORNEA ULCER; DISEASE COURSE; FEMALE; HUMAN; IMMUNOSUPPRESSIVE TREATMENT; IN VITRO STUDY; IN VIVO STUDY; INFECTION RISK; MALE; PARASITE CULTIVATION; PRIORITY JOURNAL; REVIEW; SCLERITIS; TREATMENT OUTCOME; VISUAL ACUITY;

EID: 0041528259     PISSN: 01616420     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0161-6420(03)00481-0     Document Type: Article

References (21)

1. Duguid IG, Dart JK, Morlet N, et al. Outcome of acanthamoeba keratitis treated with polyhexamethyl biguanide and propamidine. Ophthalmol 1997;104:1587-92.
2. Lee GA, Gray TB, Dart JK, et al. Acanthamoeba sclerokeratitis: treatment with systemic immunosuppression. Ophthalmol 2002;109:1178-82.
3. Elder MJ, Kilvington S, Dart JK. A clinicopathologic study of in vitro sensitivity testing and Acanthamoeba keratitis. Invest Ophthalmol Vis Sci 1994;35:1059-64.
4. Larkin DF, Kilvington S, Dart JK. Treatment of Acanthamoeba keratitis with polyhexamethylene biguanide. Ophthalmol 1992;99:185-91.
5. Hay J, Kirkness CM, Seal DV, Wright P. Drug resistance and Acanthamoeba keratitis: the quest for alternative antiprotozoal chemotherapy. Eye 1994;8:555-63.
6. Yang YF, Matheson M, Dart JK, Cree IA. Persistence of acanthamoeba antigen following acanthamoeba keratitis. Br J Ophthalmol 2001;85:277-80.
7. Allan BD, Dart JK. Strategies for the management of microbial keratitis. Br J Ophthalmol 1995;79:777-86.
8. Bacon AS, Frazer DG, Dart JK, et al. A review of 72 consecutive cases of Acanthamoeba keratitis, 1984-1992. Eye 1993; 7:719-25.
9. Illingworth CD, Cook SD, Karabatsas CH, Easty DL. Acanthamoeba keratitis: risk factors and outcome. Br J Ophthalmol 1995;79:1078-82.
10. Radford CF, Minassian DC, Dart JK. Acanthamoeba keratitis in England and Wales: incidence, outcome and risk factors. Br J Ophthalmol 2002;86:536-42.
11. Lehmann OJ, Green SM, Morlet N, et al. Polymerase chain reaction analysis of corneal epithelial and tear samples in the diagnosis of Acanthamoeba keratitis. Invest Ophthalmol Vis Sci 1998;39:1261-5.
12. Abbott RL, Zegans M, Kremer PA. Bacterial corneal ulcers. In: Tasman W, Jaeger EA, eds. Duane's Clinical Ophthalmology. Philadelphia: Lippincott Williams Wilkins, 1998;v.4, chap. 18.
13. Pérez-Santonja JJ, Lee GA, Fulcher T, et al. Acanthamoeba keratitis. Compr Ophthalmol Update 2001;2:93-104.
14. Radford CF, Lehmann OJ, Dart JK for the National Acanthamoeba keratitis Study Group. Acanthamoeba keratitis: multicentre survey in England 1992-6. Br J Ophthalmol 1998; 82:1387-92.
15. Stern GA, Buttross M. Use of corticosteroids in combination with antimicrobial drugs in the treatment of infectious corneal disease. Ophthalmology 1991;98:847-53.
16. Park DH, Palay DA, Daya SM, et al. The role of topical corticosteroids in the management of Acanthamoeba keratitis. Cornea 1997;16:277-83.
17. Illingworth CD, Cook SD. Acanthamoeba keratitis. Surv Ophthalmol 1998;42:493-508.
18. Bacon AS, Dart JK, Ficker LA, et al. Acanthamoeba keratitis. The value of early diagnosis. Ophthalmol 1993;100: 1238-43.
19. Ficker LA, Kirkness C, Wright P. Prognosis for keratoplasty in Acanthamoeba keratitis. Ophthalmol 1993;100:105-10.
20. Murdoch D, Gray TB, Cursons R, Parr D. Acanthamoeba keratitis in New Zealand, including two cases with in vivo resistance to polyhexamethylene biguanide. Aust N Z J Ophthalmol 1998;26:231-6.
21. Kosrirukvongs P, Wanachiwanawin D, Visvesvara GS. Treatment of Acanthamoeba keratitis with chlorhexidine. Ophthalmol 1999;106:798-802.