-
1
-
-
0025369344
-
A phase I clinical trial and pharmacokinetic evaluation of liposome-encapsulated doxorubicin
-
Rahman A, Treat J, Roh JK, Potkul LA, Alvord WG, Forst D, and PV Woolley: A phase I clinical trial and pharmacokinetic evaluation of liposome-encapsulated doxorubicin. J Clin Oncol 8: 1093-1100, 1990.
-
(1990)
J Clin Oncol
, vol.8
, pp. 1093-1100
-
-
Rahman, A.1
Treat, J.2
Roh, J.K.3
Potkul, L.A.4
Alvord, W.G.5
Forst, D.6
Woolley, P.V.7
-
2
-
-
0027162899
-
Prolongation of the circulation time of doxorubicin encapsulated in liposomes containing a polyethylene glycol-derivatized phospholipid: Pharmacokinetic studies in rodents and dogs
-
Gabizon AA, Barenholz Y and Bialer M: Prolongation of the circulation time of doxorubicin encapsulated in liposomes containing a polyethylene glycol- derivatized phospholipid: pharmacokinetic studies in rodents and dogs. Pharm Res 10: 703-708, 1993.
-
(1993)
Pharm Res
, vol.10
, pp. 703-708
-
-
Gabizon, A.A.1
Barenholz, Y.2
Bialer, M.3
-
3
-
-
0026352832
-
Sterically stabilized liposomes: Improvements in pharmacokinetics and antitumor therapeutic efficacy
-
Papahadjopoulos D, Allen TM, Gabizon A, Mayhew E, Matthay K, Huang SK, Lee K, Woodle MC, Lasic DD, Redemann C and Martin FJ: Sterically stabilized liposomes: improvements in pharmacokinetics and antitumor therapeutic efficacy. Proc Natl Acad Sci USA 88: 11460-11644, 1991.
-
(1991)
Proc Natl Acad Sci USA
, vol.88
, pp. 11460-11644
-
-
Papahadjopoulos, D.1
Allen, T.M.2
Gabizon, A.3
Mayhew, E.4
Matthay, K.5
Huang, S.K.6
Lee, K.7
Woodle, M.C.8
Lasic, D.D.9
Redemann, C.10
Martin, F.J.11
-
4
-
-
0027242138
-
Increased microvascular permeability contributes to preferential accumulation of Stealth liposomes in tumor tissue
-
Wu NZ, Da D, Rudoll TL, Needham D, Whorton AR and Dewhirst MW: Increased microvascular permeability contributes to preferential accumulation of Stealth liposomes in tumor tissue. Cancer Res 53: 3765-3770, 1993.
-
(1993)
Cancer Res
, vol.53
, pp. 3765-3770
-
-
Wu, N.Z.1
Da, D.2
Rudoll, T.L.3
Needham, D.4
Whorton, A.R.5
Dewhirst, M.W.6
-
5
-
-
0028304405
-
Microvascular permeability and interstitial penetration of sterically stabilized (stealth) liposomes in a human tumor xenograft
-
Yuan F, Leunig M, Huang SK, Berk DA, Papahadjopoulos D, and Jain RK: Microvascular permeability and interstitial penetration of sterically stabilized (stealth) liposomes in a human tumor xenograft. Cancer Res 54: 3352-3356, 1994.
-
(1994)
Cancer Res
, vol.54
, pp. 3352-3356
-
-
Yuan, F.1
Leunig, M.2
Huang, S.K.3
Berk, D.A.4
Papahadjopoulos, D.5
Jain, R.K.6
-
6
-
-
0026733476
-
Microscopic localization of sterically stabilized liposomes in colon carcinoma-bearing mice
-
Huang SK, Lee KD, Hong K, Friend DS and Papahadjopoulos D: Microscopic localization of sterically stabilized liposomes in colon carcinoma-bearing mice. Cancer Res 52: 5135-5143, 1992.
-
(1992)
Cancer Res
, vol.52
, pp. 5135-5143
-
-
Huang, S.K.1
Lee, K.D.2
Hong, K.3
Friend, D.S.4
Papahadjopoulos, D.5
-
7
-
-
0027050420
-
Pharmacokinetics and therapeutics of sterically stabilized liposomes in mice bearing C-26 colon carcinoma
-
Huang SK, Mayhew E, Gilani S, Lasic DD, Martin FJ and Papahadjopoulos D: Pharmacokinetics and therapeutics of sterically stabilized liposomes in mice bearing C-26 colon carcinoma. Cancer Res 52: 6774-6781, 1992.
-
(1992)
Cancer Res
, vol.52
, pp. 6774-6781
-
-
Huang, S.K.1
Mayhew, E.2
Gilani, S.3
Lasic, D.D.4
Martin, F.J.5
Papahadjopoulos, D.6
-
8
-
-
0027213484
-
Arrest of human lung tumor xenograft growth in severe combined immunodeficient mice using doxorubicin encapsulated in sterically stabilized liposomes
-
Williams SS, Alosco TR, Mayhew E, Lasic DD, Martin FJ and Bankert RB: Arrest of human lung tumor xenograft growth in severe combined immunodeficient mice using doxorubicin encapsulated in sterically stabilized liposomes. Cancer Res 53: 3964-3967, 1993.
-
(1993)
Cancer Res
, vol.53
, pp. 3964-3967
-
-
Williams, S.S.1
Alosco, T.R.2
Mayhew, E.3
Lasic, D.D.4
Martin, F.J.5
Bankert, R.B.6
-
9
-
-
0029585915
-
Doxorubicin encapsulated in sterically stabilized liposomes for the treatment of a brain tumor model: Biodistribution and therapeutic efficacy
-
Siegal T, Horowitz A and Gabizon A: Doxorubicin encapsulated in sterically stabilized liposomes for the treatment of a brain tumor model: biodistribution and therapeutic efficacy. J Neurosurg 83: 1029-1037, 1995.
-
(1995)
J Neurosurg
, vol.83
, pp. 1029-1037
-
-
Siegal, T.1
Horowitz, A.2
Gabizon, A.3
-
10
-
-
0033734065
-
High intratumoural accumulation of stealth liposomal doxorubicin (Caelyx) in glioblastomas and in metastatic brain tumours
-
Koukourakis MI, Koukouraki S, Fezoulidis I, Kelekis N, Kyrias G, Archimandritis S and Karkavitsas N: High intratumoural accumulation of stealth liposomal doxorubicin (Caelyx) in glioblastomas and in metastatic brain tumours. Br J Cancer 83: 1281-1286, 2000.
-
(2000)
Br J Cancer
, vol.83
, pp. 1281-1286
-
-
Koukourakis, M.I.1
Koukouraki, S.2
Fezoulidis, I.3
Kelekis, N.4
Kyrias, G.5
Archimandritis, S.6
Karkavitsas, N.7
-
11
-
-
0021029382
-
Prevention of chronic doxorubicin cardiotoxicity in beagles by liposomal encapsulation
-
Herman EH, Rahman A, Ferrans VJ, Vick JA and Schein PS: Prevention of chronic doxorubicin cardiotoxicity in beagles by liposomal encapsulation. Cancer Res 43: 5427-5432, 1983.
-
(1983)
Cancer Res
, vol.43
, pp. 5427-5432
-
-
Herman, E.H.1
Rahman, A.2
Ferrans, V.J.3
Vick, J.A.4
Schein, P.S.5
-
12
-
-
0035005359
-
Pegylated liposomal doxorubicin: Metamorphosis of an old drug into a new form of chemotherapy
-
Gabizon AA: Pegylated liposomal doxorubicin: metamorphosis of an old drug into a new form of chemotherapy. Cancer Invest 19: 424-436, 2001.
-
(2001)
Cancer Invest
, vol.19
, pp. 424-436
-
-
Gabizon, A.A.1
-
13
-
-
0031941991
-
Randomized comparative trial of pegylated liposomal doxorubicin versus bleomycin and vincristine in the treatment of AIDS-related Kaposi's sarcoma
-
International Pegylated Liposomal Doxorubicin study Group
-
Stewart S, Jablonowski H, Goebel FI3 FD, Arasteh K, Spittle M, Rios A, Aboulafia D, Galleshaw J and Dezube BJ: Randomized comparative trial of pegylated liposomal doxorubicin versus bleomycin and vincristine in the treatment of AIDS-related Kaposi's sarcoma. International Pegylated Liposomal Doxorubicin study Group. J Clin Oncol 16: 683-691, 1998.
-
(1998)
J Clin Oncol
, vol.16
, pp. 683-691
-
-
Stewart, S.1
Jablonowski, H.2
Goebel, F.D.3
Arasteh, K.4
Spittle, M.5
Rios, A.6
Aboulafia, D.7
Galleshaw, J.8
Dezube, B.J.9
-
14
-
-
0031861021
-
Pegylated-liposomal doxorubicin versus doxorubicin, bleomycin, and vincristine in the treatment of AIDS-related Kaposi's sarcoma: Results of a randomized phase III clinical trial
-
Northfelt DW, Dezube BJ, Thommes JA, Miller BJ, Fischl MA, Friedman-Kien A, Kaplan LD, Du Mond C, Mamelok RD and Henry DH: Pegylated-liposomal doxorubicin versus doxorubicin, bleomycin, and vincristine in the treatment of AIDS-related Kaposi's sarcoma: results of a randomized phase III clinical trial J Clin Oncol 16: 2445-2451, 1998.
-
(1998)
J Clin Oncol
, vol.16
, pp. 2445-2451
-
-
Northfelt, D.W.1
Dezube, B.J.2
Thommes, J.A.3
Miller, B.J.4
Fischl, M.A.5
Friedman-Kien, A.6
Kaplan, L.D.7
Du Mond, C.8
Mamelok, R.D.9
Henry, D.H.10
-
15
-
-
0036420885
-
Pegylated liposomal doxorubicin (Doxil) for metastatic breast cancer: The Cancer Research Network, Inc., experience
-
Perez AT, Domenech GH, Frankel C and Vogel CL: Pegylated liposomal doxorubicin (Doxil) for metastatic breast cancer: the Cancer Research Network, Inc., experience. Cancer Invest 20 (Suppl 2): 22-9, 2002.
-
(2002)
Cancer Invest
, vol.20
, Issue.SUPPL. 2
, pp. 22-29
-
-
Perez, A.T.1
Domenech, G.H.2
Frankel, C.3
Vogel, C.L.4
-
16
-
-
0031055830
-
Phase II study of liposomal doxorubicin in refractory ovarian cancer: Antitumor activity and toxicity modification by liposomal encapsulation
-
Muggia FM, Hainsworth JD, Jeffers S, Miller P, Groshen S, Tan M, Roman L, Uziely B, Muderspach L, Garcia A, Burnett A, Greco FA, Morrow CP, Paradiso LJ and Liang LJ: Phase II study of liposomal doxorubicin in refractory ovarian cancer: antitumor activity and toxicity modification by liposomal encapsulation J Clin Oncol 15: 987-993, 1997.
-
(1997)
J Clin Oncol
, vol.15
, pp. 987-993
-
-
Muggia, F.M.1
Hainsworth, J.D.2
Jeffers, S.3
Miller, P.4
Groshen, S.5
Tan, M.6
Roman, L.7
Uziely, B.8
Muderspach, L.9
Garcia, A.10
Burnett, A.11
Greco, F.A.12
Morrow, C.P.13
Paradiso, L.J.14
Liang, L.J.15
-
17
-
-
0033850066
-
Phase II study of liposomal doxorubicin in platinum- and paclitaxel-refractory epithelial ovarian cancer
-
Gordon AN, Granai CO, Rose PG, Hainsworth J, Lopez A, Weissman C, Rosales R and Sharpington T: Phase II study of liposomal doxorubicin in platinum- and paclitaxel-refractory epithelial ovarian cancer. J Clin Oncol 18: 3093-3100, 2000.
-
(2000)
J Clin Oncol
, vol.18
, pp. 3093-3100
-
-
Gordon, A.N.1
Granai, C.O.2
Rose, P.G.3
Hainsworth, J.4
Lopez, A.5
Weissman, C.6
Rosales, R.7
Sharpington, T.8
-
18
-
-
0035879099
-
Recurrent epithelial ovarian carcinoma: A randomized phase III study of pegylated liposomal doxorubicin versus topotecan
-
Gordon AN, Fleagle JT, Guthrie D, Parkin DE, Gore ME and Lacave AJ: Recurrent epithelial ovarian carcinoma: a randomized phase III study of pegylated liposomal doxorubicin versus topotecan. J Clin Oncol 19: 3312-3322, 2001.
-
(2001)
J Clin Oncol
, vol.19
, pp. 3312-3322
-
-
Gordon, A.N.1
Fleagle, J.T.2
Guthrie, D.3
Parkin, D.E.4
Gore, M.E.5
Lacave, A.J.6
-
19
-
-
0029038996
-
Liposomal doxorubicin: Antitumor activity and unique toxicities during two complementary phase I studies
-
Uziely B, Jeffers S, Isacson R, Kutsch K, Wei-Tsao D, Yehoshua Z, Libson E, Muggia FM and Gabizon A: Liposomal doxorubicin: antitumor activity and unique toxicities during two complementary phase I studies. J Clin Oncol 13: 1777-1785, 1995.
-
(1995)
J Clin Oncol
, vol.13
, pp. 1777-1785
-
-
Uziely, B.1
Jeffers, S.2
Isacson, R.3
Kutsch, K.4
Wei-Tsao, D.5
Yehoshua, Z.6
Libson, E.7
Muggia, F.M.8
Gabizon, A.9
-
20
-
-
0032168673
-
Clinical development of platinum complexes in cancer therapy: An historical perspective and an update
-
Lebwohl D and Canetta R: Clinical development of platinum complexes in cancer therapy: an historical perspective and an update. Eur J Cancer 34: 1522-1534, 1998.
-
(1998)
Eur J Cancer
, vol.34
, pp. 1522-1534
-
-
Lebwohl, D.1
Canetta, R.2
-
21
-
-
0028948614
-
Impact of doxorubicin on survival in advanced ovarian cancer
-
A'Hern RP and Gore ME. Impact of doxorubicin on survival in advanced ovarian cancer. J Clin Oncol 13: 726-732, 1995.
-
(1995)
J Clin Oncol
, vol.13
, pp. 726-732
-
-
A'Hern, R.P.1
Gore, M.E.2
-
22
-
-
0025148278
-
Continual reassessment method: A practical design for phase I clinical trials in cancer
-
O'Quigley J, Pepe M and Fisher L: Continual reassessment method: a practical design for phase I clinical trials in cancer. Biometrics 46: 33-48, 1990.
-
(1990)
Biometrics
, vol.46
, pp. 33-48
-
-
O'Quigley, J.1
Pepe, M.2
Fisher, L.3
-
23
-
-
0034793680
-
Phase I study of doxil-cisplatin combination chemotherapy in patients with advanced malignancies
-
Lyass O, Hubert A and Gabizon AA: Phase I study of doxil-cisplatin combination chemotherapy in patients with advanced malignancies. Clin Cancer Res 7: 3040-3046, 2001.
-
(2001)
Clin Cancer Res
, vol.7
, pp. 3040-3046
-
-
Lyass, O.1
Hubert, A.2
Gabizon, A.A.3
-
24
-
-
4243826373
-
Apparent protection of Doxil skin and oral toxicities when combined with cisplatin: Results of a Phase I study
-
Klein P, Wasserheit C, Hochster H, Chachoua A, Speyer JL, Oratz R, Downey A, Sorich J, Kotcher L, Eisenberg T and Muggia F: Apparent protection of Doxil skin and oral toxicities when combined with cisplatin: results of a Phase I study. Proc Am Soc Clin Oncol 18: 217a, 1999.
-
(1999)
Proc Am Soc Clin Oncol
, vol.18
-
-
Klein, P.1
Wasserheit, C.2
Hochster, H.3
Chachoua, A.4
Speyer, J.L.5
Oratz, R.6
Downey, A.7
Sorich, J.8
Kotcher, L.9
Eisenberg, T.10
Muggia, F.11
-
25
-
-
0030959798
-
Treatment of advanced breast cancer with sterically stabilized liposomal doxorubicin: Results of a multicenter phase II trial
-
Ranson MR, Carmichael J, O'Byrne K, Stewart S, Smith D and Howell A: Treatment of advanced breast cancer with sterically stabilized liposomal doxorubicin: results of a multicenter phase II trial. J Clin Oncol 15: 3185-3191, 1997.
-
(1997)
J Clin Oncol
, vol.15
, pp. 3185-3191
-
-
Ranson, M.R.1
Carmichael, J.2
O'Byrne, K.3
Stewart, S.4
Smith, D.5
Howell, A.6
|