Substituent effect on the reductive N-dearylation of 3-(indol-1-yl)-1,2-benzisoxazoles by rat liver microsomes

Drug Metabolism and Disposition

Volumn 31, Issue 8, 2003, Pages 999-1004

  Tschirret Guth, Richard A ^a   Wood, Harold B ^a  

^a MERCK RESEARCH LABORATORIES   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMIDINE; CARBON MONOXIDE; CYTOCHROME P450; ISOXAZOLE DERIVATIVE; KETOCONAZOLE;

AIR; ANAEROBIC METABOLISM; ARTICLE; CHEMICAL REACTION; CORRELATION ANALYSIS; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; LIVER MICROSOME; MATHEMATICAL COMPUTING; MICHAELIS CONSTANT; PRIORITY JOURNAL; QUANTITATIVE ANALYSIS; REDUCTION; XENOBIOTIC METABOLISM;

AIR; AMIDINES; ANIMALS; CARBON MONOXIDE; CHEMISTRY, ANALYTICAL; CYTOCHROME P-450 ENZYME SYSTEM; ELECTRONS; INDOLES; ISOXAZOLES; KETOCONAZOLE; MICROSOMES, LIVER; MOLECULAR STRUCTURE; NADP; OXAZOLES; OXIDATION-REDUCTION; RATS; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 0041524286     PISSN: 00909556     EISSN: None     Source Type: Journal    
DOI: 10.1124/dmd.31.8.999     Document Type: Article

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