Phlorizin treatment prevents the decrease in plasma insulin levels but not the progressive histopathological changes in the pancreatic islets during aging of Zucker diabetic fatty rats

Journal of Endocrinological Investigation

Volumn 26, Issue 6, 2003, Pages 508-515

  Janssen, S W J ^a,b   Martens, G J M ^a   Sweep, C G J ^b   Span, P N ^b   Verhofstad, A A J ^b   Hermus, A R M M ^b  

^a RADBOUD UNIVERSITY NIJMEGEN   (Netherlands)

^b RADBOUD UNIVERSITY MEDICAL CENTER   (Netherlands)

Author keywords

Diabetes mellitus; Glucose toxicity; IAPP PC1; Insulin; PC2; ZDF rat

Indexed keywords

AMYLIN; FURIN; GLUCOSE; INSULIN; MESSENGER RNA; PHLORIZIN;

AGING; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CELL DISRUPTION; CELL NUCLEUS MATRIX; CELL ULTRASTRUCTURE; CONTROLLED STUDY; DRUG BLOOD LEVEL; DRUG EFFECT; GLUCOSE BLOOD LEVEL; GLUCOSE TRANSPORT; HYPERGLYCEMIA; IMMUNOHISTOCHEMISTRY; INSULIN BLOOD LEVEL; KIDNEY; MALE; MITOCHONDRION; NON INSULIN DEPENDENT DIABETES MELLITUS; NONHUMAN; PANCREAS ISLET DISEASE; PROTEIN EXPRESSION; RAT; RAT STRAIN; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; WEIGHT GAIN;

EID: 0041524014     PISSN: 03914097     EISSN: None     Source Type: Journal    
DOI: 10.1007/BF03345212     Document Type: Article

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