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Volumn 1, Issue 2, 2002, Pages 111-118

Genetic targeting of cerebellar Purkinje cells: History, current status and novel strategies

Author keywords

Cerebellum; Gene targeting; Purkinje cells

Indexed keywords

CEREBELLUM; GENE TARGETING; GENETIC ENGINEERING; PRIORITY JOURNAL; PURKINJE CELL; REVIEW; TRANSGENE; ANIMAL; CONVALESCENCE; GENE DELETION; GENETIC RECOMBINATION; GENETICS; HUMAN; METABOLISM; METHODOLOGY; PHYSIOLOGY; TRANSGENIC ANIMAL;

EID: 0041466108     PISSN: 14734222     EISSN: 14734230     Source Type: Journal    
DOI: 10.1080/147342202753671240     Document Type: Review
Times cited : (7)

References (83)
  • 1
    • 0030467935 scopus 로고    scopus 로고
    • The cerebellum: Cortical processing and theory
    • De Schutter E, Maex R. The cerebellum: cortical processing and theory. Curr Opin Neurobiol 1996; 6: 759-764.
    • (1996) Curr Opin Neurobiol , vol.6 , pp. 759-764
    • De Schutter, E.1    Maex, R.2
  • 2
    • 0030625671 scopus 로고    scopus 로고
    • Duality of cerebellar motor and cognitive functions
    • Bloedel JR, Bracha V. Duality of cerebellar motor and cognitive functions. Int Rev Neurobiol 1997; 41: 613-634.
    • (1997) Int Rev Neurobiol , vol.41 , pp. 613-634
    • Bloedel, J.R.1    Bracha, V.2
  • 3
    • 0031465549 scopus 로고    scopus 로고
    • The detection and generation of sequences as a key to cerebellar function: Experiments and theory
    • Braitenberg V, Heck D, Sultan F. The detection and generation of sequences as a key to cerebellar function: experiments and theory. Behav Brain Sci 1997; 20: 229-245.
    • (1997) Behav Brain Sci , vol.20 , pp. 229-245
    • Braitenberg, V.1    Heck, D.2    Sultan, F.3
  • 4
    • 0030982202 scopus 로고    scopus 로고
    • Prediction and preparation, fundamental functions of the cerebellum
    • Courchesne E, Allen G. Prediction and preparation, fundamental functions of the cerebellum. Learn Mem 1997; 4: 1-35.
    • (1997) Learn Mem , vol.4 , pp. 1-35
    • Courchesne, E.1    Allen, G.2
  • 5
    • 0030957946 scopus 로고    scopus 로고
    • On the role of the cerebellum and basal ganglia in cognitive signal processing
    • Houk JC. On the role of the cerebellum and basal ganglia in cognitive signal processing. Prog Brain Res 1997; 114: 543-552.
    • (1997) Prog Brain Res , vol.114 , pp. 543-552
    • Houk, J.C.1
  • 6
    • 0030953675 scopus 로고    scopus 로고
    • The cerebellum, LTD, and memory: Alternative views
    • Llinas R, Lang EJ, Welsh JP. The cerebellum, LTD, and memory: alternative views. Learn Mem 1997; 3: 445-155.
    • (1997) Learn Mem , vol.3 , pp. 445-1155
    • Llinas, R.1    Lang, E.J.2    Welsh, J.P.3
  • 7
    • 0031205071 scopus 로고    scopus 로고
    • Cerebellum and cerebrum in adaptive control and cognition: A review
    • Parkins EJ. Cerebellum and cerebrum in adaptive control and cognition: a review. Biol Cybern 1997; 77: 79-87.
    • (1997) Biol Cybern , vol.77 , pp. 79-87
    • Parkins, E.J.1
  • 8
    • 0032123560 scopus 로고    scopus 로고
    • A role for the cerebellum in learning movement coordination
    • Thach WT. A role for the cerebellum in learning movement coordination. Neurobiol Learn Mem 1998; 70: 177-188.
    • (1998) Neurobiol Learn Mem , vol.70 , pp. 177-188
    • Thach, W.T.1
  • 9
    • 0034054982 scopus 로고    scopus 로고
    • Imaging cognition II: An empirical review of 275 PET and fMRI studies
    • Cabeza R, Nyberg L. Imaging cognition II: an empirical review of 275 PET and fMRI studies. J Cogn Neurosci 2000; 12: 1-47.
    • (2000) J Cogn Neurosci , vol.12 , pp. 1-47
    • Cabeza, R.1    Nyberg, L.2
  • 10
    • 0034644107 scopus 로고    scopus 로고
    • Cerebellar function: Coordination, learning or timing?
    • Mauk MD, Medina JF, Nores WL, Ohyama T. Cerebellar function: coordination, learning or timing? Curr Biol 2000; 10: R522-R525
    • (2000) Curr Biol , vol.10
    • Mauk, M.D.1    Medina, J.F.2    Nores, W.L.3    Ohyama, T.4
  • 11
    • 0030446363 scopus 로고    scopus 로고
    • The essential role of hippocampal CA1 NMDA receptor-dependent synaptic plasticity in spatial memory
    • Tsien JZ, Huerta PT, Tonegawa S. The essential role of hippocampal CA1 NMDA receptor-dependent synaptic plasticity in spatial memory. Cell 1996; 87: 1327-1338.
    • (1996) Cell , vol.87 , pp. 1327-1338
    • Tsien, J.Z.1    Huerta, P.T.2    Tonegawa, S.3
  • 12
    • 0024039160 scopus 로고
    • A Purkinje cell differentiation marker shows a partial DNA sequence homology to the cellular sis/PDGF2 gene
    • Oberdick J, Levinthal F, Levinthal C. A Purkinje cell differentiation marker shows a partial DNA sequence homology to the cellular sis/PDGF2 gene. Neuron 1988; 1: 367-376.
    • (1988) Neuron , vol.1 , pp. 367-376
    • Oberdick, J.1    Levinthal, F.2    Levinthal, C.3
  • 13
    • 0024263699 scopus 로고
    • cDNA cloning and characterization of three genes uniquely expressed in cerebellum by Purkinje neurons
    • Nordquist DT, Kozak CA, Orr HT. cDNA cloning and characterization of three genes uniquely expressed in cerebellum by Purkinje neurons. J Neurosci 1988; 8: 4780-1789.
    • (1988) J Neurosci , vol.8 , pp. 4780-11789
    • Nordquist, D.T.1    Kozak, C.A.2    Orr, H.T.3
  • 15
    • 0028710076 scopus 로고
    • Mouse chromosome 8
    • Ceci JD. Mouse chromosome 8. Mamm Genome 1994; 5: S124-S138
    • (1994) Mamm Genome , vol.5
    • Ceci, J.D.1
  • 16
    • 0027284951 scopus 로고
    • Control of segment-like patterns of gene expression in the mouse cerebellum
    • Oberdick J, Schilling K, Smeyne RJ, et al. Control of segment-like patterns of gene expression in the mouse cerebellum. Neuron 1993; 10: 1007-1018.
    • (1993) Neuron , vol.10 , pp. 1007-1018
    • Oberdick, J.1    Schilling, K.2    Smeyne, R.J.3
  • 17
    • 0025815843 scopus 로고
    • Purkinje cell protein-2 regulatory regions and transgene expression in cerebellar compartments
    • Vandaele S, Nordquist DT, Feddersen RM, et al. Purkinje cell protein-2 regulatory regions and transgene expression in cerebellar compartments. Genes Dev 1991; 5: 1136-1148.
    • (1991) Genes Dev , vol.5 , pp. 1136-1148
    • Vandaele, S.1    Nordquist, D.T.2    Feddersen, R.M.3
  • 18
    • 0033574522 scopus 로고    scopus 로고
    • Interaction of heterotrimeric G protein galphao with Purkinje cell protein-2. Evidence for a novel nucleotide exchange factor
    • Luo Y, Denker BM. Interaction of heterotrimeric G protein galphao with Purkinje cell protein-2. Evidence for a novel nucleotide exchange factor. J Biol Chem 1999; 274: 10685-10688.
    • (1999) J Biol Chem , vol.274 , pp. 10685-10688
    • Luo, Y.1    Denker, B.M.2
  • 19
    • 0035340989 scopus 로고    scopus 로고
    • Inhibition of GDP/GTP exchange on G alpha subunits by proteins containing G-protein regulatory motifs
    • Natochin M, Gasimov KG, Artemyev NO. Inhibition of GDP/GTP exchange on G alpha subunits by proteins containing G-protein regulatory motifs. Biochemistry 2001; 40: 5322-5328.
    • (2001) Biochemistry , vol.40 , pp. 5322-5328
    • Natochin, M.1    Gasimov, K.G.2    Artemyev, N.O.3
  • 20
    • 0025259637 scopus 로고
    • A promoter that drives transgene expression in cerebellar Purkinje and retinal bipolar neurons
    • Oberdick J, Smeyne RJ, Mann JR, Zackson S, Morgan JI. A promoter that drives transgene expression in cerebellar Purkinje and retinal bipolar neurons. Science 1990; 248: 223-226.
    • (1990) Science , vol.248 , pp. 223-226
    • Oberdick, J.1    Smeyne, R.J.2    Mann, J.R.3    Zackson, S.4    Morgan, J.I.5
  • 21
    • 0025793627 scopus 로고
    • Cerebellar Purkinje cell markers are expressed in retinal bipolar neurons
    • Berrebi AS, Oberdick J, Sangameswaran L, et al. Cerebellar Purkinje cell markers are expressed in retinal bipolar neurons. J Comp Neurol 1991; 308: 630-649.
    • (1991) J Comp Neurol , vol.308 , pp. 630-649
    • Berrebi, A.S.1    Oberdick, J.2    Sangameswaran, L.3
  • 22
    • 0026583067 scopus 로고
    • Characteristics of labeling of the cerebellar Purkinje neuron by L7 antiserum
    • Berrebi AS, Mugnaini E. Characteristics of labeling of the cerebellar Purkinje neuron by L7 antiserum. J Chem Neuroanat 1992; 5: 235-243.
    • (1992) J Chem Neuroanat , vol.5 , pp. 235-243
    • Berrebi, A.S.1    Mugnaini, E.2
  • 23
    • 0030999639 scopus 로고    scopus 로고
    • Absence of neuroanatomical and behavioral deficits in L7/pcp-2-null mice
    • Vassileva G, Smeyne RJ, Morgan JI. Absence of neuroanatomical and behavioral deficits in L7/pcp-2-null mice. Brain Res Mol Brain Res 1997; 46: 333-337.
    • (1997) Brain Res Mol Brain Res , vol.46 , pp. 333-337
    • Vassileva, G.1    Smeyne, R.J.2    Morgan, J.I.3
  • 24
    • 0030945774 scopus 로고    scopus 로고
    • Phenotypic analysis of mice lacking the highly abundant Purkinje cell- and bipolar neuron-specific PCP2 protein
    • Mohn AR, Feddersen RM, Nguyen MS, Koller BH. Phenotypic analysis of mice lacking the highly abundant Purkinje cell- and bipolar neuron-specific PCP2 protein. Mol Cell Neurosci 1997; 9: 63-76.
    • (1997) Mol Cell Neurosci , vol.9 , pp. 63-76
    • Mohn, A.R.1    Feddersen, R.M.2    Nguyen, M.S.3    Koller, B.H.4
  • 25
    • 0026331270 scopus 로고
    • Dynamic organization of developing Purkinje cells revealed by transgene expression
    • Smeyne RJ, Oberdick J, Schilling K, et al. Dynamic organization of developing Purkinje cells revealed by transgene expression. Science 1991; 254: 719-721.
    • (1991) Science , vol.254 , pp. 719-721
    • Smeyne, R.J.1    Oberdick, J.2    Schilling, K.3
  • 26
    • 0026492630 scopus 로고
    • Disrupted cerebellar cortical development and progressive degeneration of Purkinje cells in SV40 T antigen transgenic mice
    • Feddersen RM, Ehlenfeldt R, Yunis WS, Clark HB, Orr HT. Disrupted cerebellar cortical development and progressive degeneration of Purkinje cells in SV40 T antigen transgenic mice. Neuron 1992; 9: 955-966.
    • (1992) Neuron , vol.9 , pp. 955-966
    • Feddersen, R.M.1    Ehlenfeldt, R.2    Yunis, W.S.3    Clark, H.B.4    Orr, H.T.5
  • 27
    • 0029018228 scopus 로고
    • In vivo viability of postmitotic Purkinje neurons requires pRb family member function
    • Feddersen RM, Clark HB, Yunis WS, Orr HT. In vivo viability of postmitotic Purkinje neurons requires pRb family member function. Mol Cell Neurosci 1995; 6: 153-167.
    • (1995) Mol Cell Neurosci , vol.6 , pp. 153-167
    • Feddersen, R.M.1    Clark, H.B.2    Yunis, W.S.3    Orr, H.T.4
  • 28
    • 0030900851 scopus 로고    scopus 로고
    • Susceptibility to cell death induced by mutant SV40 T-antigen correlates with Purkinje neuron functional development
    • Feddersen RM, Yunis WS, O'Donnell MA, et al. Susceptibility to cell death induced by mutant SV40 T-antigen correlates with Purkinje neuron functional development. Mol Cell Neurosci 1997; 9: 42-62.
    • (1997) Mol Cell Neurosci , vol.9 , pp. 42-62
    • Feddersen, R.M.1    Yunis, W.S.2    O'Donnell, M.A.3
  • 29
    • 0031887524 scopus 로고    scopus 로고
    • Cerebellar vascular and synaptic responses in normal mice and in transgenics with Purkinje-cell dysfunction
    • Yang G, Feddersen RM, Zhang FY, et al. Cerebellar vascular and synaptic responses in normal mice and in transgenics with Purkinje-cell dysfunction. Am J Physiol Regul Integr Comp Physiol 1998; 43: R529-R540
    • (1998) Am J Physiol Regul Integr Comp Physiol , vol.43
    • Yang, G.1    Feddersen, R.M.2    Zhang, F.Y.3
  • 30
    • 0031727324 scopus 로고    scopus 로고
    • The transcription factor E2F-1 in SV40 T antigen-induced cerebellar Purkinje cell degeneration
    • Athanasiou MC, Yunis W, Coleman N, et al. The transcription factor E2F-1 in SV40 T antigen-induced cerebellar Purkinje cell degeneration. Mol Cell Neurosci 1998; 12: 16-28.
    • (1998) Mol Cell Neurosci , vol.12 , pp. 16-28
    • Athanasiou, M.C.1    Yunis, W.2    Coleman, N.3
  • 31
    • 0029163222 scopus 로고
    • SCA1 transgenic mice - A model for neurodegeneration caused by an expanded cag trinucleotide repeat
    • Burright EN, Clark HB, Servadio A, et al. SCA1 transgenic mice-a model for neurodegeneration caused by an expanded cag trinucleotide repeat. Cell 1995; 82: 937-948.
    • (1995) Cell , vol.82 , pp. 937-948
    • Burright, E.N.1    Clark, H.B.2    Servadio, A.3
  • 32
    • 3142516072 scopus 로고
    • SCA1 transgenic mice - A model for neurodegeneration caused by cag trinucleotide expansion
    • Burright EN, Clark HB, Servadio A, et al. SCA1 transgenic mice-a model for neurodegeneration caused by cag trinucleotide expansion. Am J Hum Genet 1995; 57: 8.
    • (1995) Am J Hum Genet , vol.57 , pp. 8
    • Burright, E.N.1    Clark, H.B.2    Servadio, A.3
  • 33
    • 0030864463 scopus 로고    scopus 로고
    • Purkinje-cell expression of a mutant allele of SCA1 in transgenic mice leads to disparate effects on motor behaviors, followed by a progressive cerebellar dysfunction and histological alterations
    • Clark HB, Burright EN, Yunis WS, et al. Purkinje-cell expression of a mutant allele of SCA1 in transgenic mice leads to disparate effects on motor behaviors, followed by a progressive cerebellar dysfunction and histological alterations. J Neurosci 1997; 17: 7385-7395.
    • (1997) J Neurosci , vol.17 , pp. 7385-7395
    • Clark, H.B.1    Burright, E.N.2    Yunis, W.S.3
  • 34
    • 0035070146 scopus 로고    scopus 로고
    • Calcium dynamics and electrophysiological properties of cerebellar Purkinje cells in SCA1 transgenic mice
    • Inoue T, Lin X, Kohlmeier KA, et al. Calcium dynamics and electrophysiological properties of cerebellar Purkinje cells in SCA1 transgenic mice. J Neurophysiol 2001; 85: 1750-1760.
    • (2001) J Neurophysiol , vol.85 , pp. 1750-1760
    • Inoue, T.1    Lin, X.2    Kohlmeier, K.A.3
  • 35
    • 0030666001 scopus 로고    scopus 로고
    • Ataxin-1 with an expanded glutamine tract alters nuclear matrix-associated structures
    • Skinner PJ, Koshy BT, Cummings CJ, et al. Ataxin-1 with an expanded glutamine tract alters nuclear matrix-associated structures. Nature 1997; 389: 971-974.
    • (1997) Nature , vol.389 , pp. 971-974
    • Skinner, P.J.1    Koshy, B.T.2    Cummings, C.J.3
  • 36
    • 0032475941 scopus 로고    scopus 로고
    • Ataxin-1 nuclear-localization and aggregation-role in polyglutamine-induced disease in SCA1 transgenic mice
    • Klement IA, Skinner PJ, Kaytor MD, et al. Ataxin-1 nuclear-localization and aggregation-role in polyglutamine-induced disease in SCA1 transgenic mice. Cell 1998; 95: 41-53.
    • (1998) Cell , vol.95 , pp. 41-53
    • Klement, I.A.1    Skinner, P.J.2    Kaytor, M.D.3
  • 37
    • 0034641891 scopus 로고    scopus 로고
    • Expanded polyglutamines induce neurodegeneration and trans-neuronal alterations in cerebellum and retina of SCA7 transgenic mice
    • Yvert G, Lindenberg KS, Picaud S, et al. Expanded polyglutamines induce neurodegeneration and trans-neuronal alterations in cerebellum and retina of SCA7 transgenic mice. Hum Mol Genet 2000; 9: 2491-2506.
    • (2000) Hum Mol Genet , vol.9 , pp. 2491-2506
    • Yvert, G.1    Lindenberg, K.S.2    Picaud, S.3
  • 38
    • 0028170108 scopus 로고
    • Evidence for a genetically encoded map of functional development in the cerebellum
    • Oberdick J. Evidence for a genetically encoded map of functional development in the cerebellum. Histochemistry 1994; 102: 1-14.
    • (1994) Histochemistry , vol.102 , pp. 1-14
    • Oberdick, J.1
  • 39
    • 0031690164 scopus 로고    scopus 로고
    • Regulation of a Purkinje cell-specific promoter by homeodomain proteins-repression by engrailed-2 vs. synergistic activation by hoxa5 and hoxb7
    • Sanlioglu S, Zhang XL, Baader SL, Oberdick J. Regulation of a Purkinje cell-specific promoter by homeodomain proteins-repression by engrailed-2 vs. synergistic activation by hoxa5 and hoxb7. J Neurobiol 1998; 36: 559-571.
    • (1998) J Neurobiol , vol.36 , pp. 559-571
    • Sanlioglu, S.1    Zhang, X.L.2    Baader, S.L.3    Oberdick, J.4
  • 40
    • 0029952078 scopus 로고    scopus 로고
    • Correspondence between L7-lacZ-expressing Purkinje cells and labeled olivocerebellar fibers during late embryogenesis in the mouse
    • Paradies MA, Grishkat H, Smeyne RJ, et al. Correspondence between L7-lacZ-expressing Purkinje cells and labeled olivocerebellar fibers during late embryogenesis in the mouse. J Comp Neurol 1996; 374: 451-466.
    • (1996) J Comp Neurol , vol.374 , pp. 451-466
    • Paradies, M.A.1    Grishkat, H.2    Smeyne, R.J.3
  • 41
    • 0029968221 scopus 로고    scopus 로고
    • Differential mRNA transport and the regulation of protein synthesis: Selective sensitivity of Purkinje cell dendritic mRNAs to translational inhibition
    • Bian F, Chu T, Schilling K, Oberdick J. Differential mRNA transport and the regulation of protein synthesis: selective sensitivity of Purkinje cell dendritic mRNAs to translational inhibition. Mol Cell Neurosci 1996; 7: 116-133.
    • (1996) Mol Cell Neurosci , vol.7 , pp. 116-133
    • Bian, F.1    Chu, T.2    Schilling, K.3    Oberdick, J.4
  • 42
    • 0032031999 scopus 로고    scopus 로고
    • Expression of a protein kinase C inhibitor in Purkinje cells blocks cerebellar LTD and adaptation of the vestibulo-ocular reflex
    • De Zeeuw CI, Hansel C, Bian F, et al. Expression of a protein kinase C inhibitor in Purkinje cells blocks cerebellar LTD and adaptation of the vestibulo-ocular reflex. Neuron 1998; 20: 495-508.
    • (1998) Neuron , vol.20 , pp. 495-508
    • De Zeeuw, C.I.1    Hansel, C.2    Bian, F.3
  • 43
    • 0033168293 scopus 로고    scopus 로고
    • Selective disruption of "late onset" sagittal banding patterns by ectopic expression of engrailed-2 in cerebellar Purkinje cells
    • Baader SL, Vogel MW, Sanlioglu S, Zhang X, Oberdick J. Selective disruption of "late onset" sagittal banding patterns by ectopic expression of engrailed-2 in cerebellar Purkinje cells. J Neurosci 1999; 19: 5370-5379.
    • (1999) J Neurosci , vol.19 , pp. 5370-5379
    • Baader, S.L.1    Vogel, M.W.2    Sanlioglu, S.3    Zhang, X.4    Oberdick, J.5
  • 44
    • 0033552062 scopus 로고    scopus 로고
    • Transverse zones in the vermis of the mouse cerebellum
    • Ozol K, Hayden JM, Oberdick J, Hawkes R. Transverse zones in the vermis of the mouse cerebellum. J Comp Neurol 1999; 412: 95-111.
    • (1999) J Comp Neurol , vol.412 , pp. 95-111
    • Ozol, K.1    Hayden, J.M.2    Oberdick, J.3    Hawkes, R.4
  • 45
    • 0029090783 scopus 로고
    • Local control of granule cell generation by cerebellar Purkinje cells
    • Smeyne RJ, Chu T, Lewin A, et al. Local control of granule cell generation by cerebellar Purkinje cells. Mol Cell Neurosci 1995; 6: 230-251.
    • (1995) Mol Cell Neurosci , vol.6 , pp. 230-251
    • Smeyne, R.J.1    Chu, T.2    Lewin, A.3
  • 46
    • 0030026182 scopus 로고    scopus 로고
    • Differential effects of the Rac GTPase on Purkinje cell axons and dendritic trunks and spines
    • Luo L, Hensch TK, Ackerman L, et al. Differential effects of the Rac GTPase on Purkinje cell axons and dendritic trunks and spines. Nature 1996; 379: 837-840.
    • (1996) Nature , vol.379 , pp. 837-840
    • Luo, L.1    Hensch, T.K.2    Ackerman, L.3
  • 47
    • 16944364893 scopus 로고    scopus 로고
    • Targeted overexpression of the neurite growth-associated protein b-50/gap-43 in cerebellar Purkinje cells induces sprouting after axotomy but not axon regeneration into growth-permissive transplants
    • Buffo A, Holtmaat AJDG, Savio T, et al. Targeted overexpression of the neurite growth-associated protein b-50/gap-43 in cerebellar Purkinje cells induces sprouting after axotomy but not axon regeneration into growth-permissive transplants. J Neurosci 1997; 17: 8778-8791.
    • (1997) J Neurosci , vol.17 , pp. 8778-8791
    • Buffo, A.1    Holtmaat, A.J.D.G.2    Savio, T.3
  • 48
    • 0032031559 scopus 로고    scopus 로고
    • Ectopic overexpression of engrailed-2 in cerebellar Purkinje cells causes restricted cell loss and retarded external germinal layer development at lobule junctions
    • Baader SL, Sanlioglu S, Berrebi AS, Parker-Thornburg J, Oberdick J. Ectopic overexpression of engrailed-2 in cerebellar Purkinje cells causes restricted cell loss and retarded external germinal layer development at lobule junctions. J Neurosci 1998; 18: 1763-1773.
    • (1998) J Neurosci , vol.18 , pp. 1763-1773
    • Baader, S.L.1    Sanlioglu, S.2    Berrebi, A.S.3    Parker-Thornburg, J.4    Oberdick, J.5
  • 49
    • 0031019589 scopus 로고    scopus 로고
    • Ataxia and altered dendritic calcium signaling in mice carrying a targeted null mutation of the calbindin d28k gene
    • Airaksinen MS, Eilers J, Garaschuk O, et al. Ataxia and altered dendritic calcium signaling in mice carrying a targeted null mutation of the calbindin d28k gene. Proc Natl Acad Sci USA 1997; 94: 1488-1493.
    • (1997) Proc Natl Acad Sci USA , vol.94 , pp. 1488-1493
    • Airaksinen, M.S.1    Eilers, J.2    Garaschuk, O.3
  • 50
    • 0020085878 scopus 로고
    • Calcium-binding protein distribution in the rat brain
    • Baimbridge KG, Miller JJ, Parkes CO. Calcium-binding protein distribution in the rat brain. Brain Res 1982; 239: 519-525.
    • (1982) Brain Res , vol.239 , pp. 519-525
    • Baimbridge, K.G.1    Miller, J.J.2    Parkes, C.O.3
  • 51
    • 33746473132 scopus 로고    scopus 로고
    • Precise motor co-ordination depends on the presence of calbindin D28K in cerebellar Purkinje cells
    • Barski JJ, Meyer M. Precise motor co-ordination depends on the presence of calbindin D28K in cerebellar Purkinje cells. Eur J Neurosci 2000; 12 (Suppl.): 171.
    • (2000) Eur J Neurosci , vol.12 , Issue.SUPPL. , pp. 171
    • Barski, J.J.1    Meyer, M.2
  • 52
    • 0034625542 scopus 로고    scopus 로고
    • mGluR1 in cerebellar Purkinje cells essential for long-term depression, synapse elimination, and motor coordination
    • Ichise T, Kano M, Hashimoto K, et al. mGluR1 in cerebellar Purkinje cells essential for long-term depression, synapse elimination, and motor coordination. Science 2000; 288: 1832-1835.
    • (2000) Science , vol.288 , pp. 1832-1835
    • Ichise, T.1    Kano, M.2    Hashimoto, K.3
  • 53
    • 0028149789 scopus 로고
    • Deficient cerebellar long-term depression and impaired motor learning in mGluR1 mutant mice
    • Aiba A, Kano M, Chen C, et al. Deficient cerebellar long-term depression and impaired motor learning in mGluR1 mutant mice. Cell 1994; 79: 377-388.
    • (1994) Cell , vol.79 , pp. 377-388
    • Aiba, A.1    Kano, M.2    Chen, C.3
  • 54
    • 0031035031 scopus 로고    scopus 로고
    • Persistent multiple climbing fiber innervation of cerebellar Purkinje cells in mice lacking mGluR1
    • Kano M, Hashimoto K, Kurihara H, et al. Persistent multiple climbing fiber innervation of cerebellar Purkinje cells in mice lacking mGluR1. Neuron 1997; 18: 71-79.
    • (1997) Neuron , vol.18 , pp. 71-79
    • Kano, M.1    Hashimoto, K.2    Kurihara, H.3
  • 55
    • 0027724656 scopus 로고
    • Selective expression of the glutamate receptor channel delta 2 subunit in cerebellar Purkinje cells
    • Araki K, Meguro H, Kushiya E, et al. Selective expression of the glutamate receptor channel delta 2 subunit in cerebellar Purkinje cells. Biochem Biophys Res Commun 1993; 197: 1267-1276.
    • (1993) Biochem Biophys Res Commun , vol.197 , pp. 1267-1276
    • Araki, K.1    Meguro, H.2    Kushiya, E.3
  • 56
    • 0027454751 scopus 로고
    • The rat delta-1 and delta-2 subunits extend the excitatory amino acid receptor family
    • Lomeli H, Sprengel R, Laurie DJ, et al. The rat delta-1 and delta-2 subunits extend the excitatory amino acid receptor family. FEBS Lett 1993; 315: 318-322.
    • (1993) FEBS Lett , vol.315 , pp. 318-322
    • Lomeli, H.1    Sprengel, R.2    Laurie, D.J.3
  • 57
    • 0027141312 scopus 로고
    • The differential expression of 16 NMDA and non-NMDA receptor subunits in the rat spinal cord and in periaqueductal gray
    • Tolle TR, Berthele A, Zieglgansberger W, Seeburg PH, Wisden W. The differential expression of 16 NMDA and non-NMDA receptor subunits in the rat spinal cord and in periaqueductal gray. J Neurosci 1993; 13: 5009-5028.
    • (1993) J Neurosci , vol.13 , pp. 5009-5028
    • Tolle, T.R.1    Berthele, A.2    Zieglgansberger, W.3    Seeburg, P.H.4    Wisden, W.5
  • 58
    • 0029904369 scopus 로고    scopus 로고
    • Developmental changes in expression and distribution of the glutamate receptor channel delta 2 subunit according to the Purkinje cell maturation
    • Takayama C, Nakagawa S, Watanabe M, Mishina M, Inoue Y. Developmental changes in expression and distribution of the glutamate receptor channel delta 2 subunit according to the Purkinje cell maturation. Brain Res Dev Brain Res 1996; 92: 147-155.
    • (1996) Brain Res Dev Brain Res , vol.92 , pp. 147-155
    • Takayama, C.1    Nakagawa, S.2    Watanabe, M.3    Mishina, M.4    Inoue, Y.5
  • 59
    • 0031025786 scopus 로고    scopus 로고
    • Delta-glutamate receptors are differentially distributed at parallel and climbing fiber synapses on Purkinje cells
    • Zhao HM, Wenthold RJ, Wang YX, Petralia RS. Delta-glutamate receptors are differentially distributed at parallel and climbing fiber synapses on Purkinje cells. J Neurochem 1997; 68: 1041-1052.
    • (1997) J Neurochem , vol.68 , pp. 1041-1052
    • Zhao, H.M.1    Wenthold, R.J.2    Wang, Y.X.3    Petralia, R.S.4
  • 60
    • 0028898906 scopus 로고
    • Light- and electron-microscopic localization of the glutamate receptor channel delta 2 subunit in the mouse Purkinje cell
    • Takayama C, Nakagawa S, Watanabe M, Mishina M, Inoue Y. Light- and electron-microscopic localization of the glutamate receptor channel delta 2 subunit in the mouse Purkinje cell. Neurosci Lett 1995; 188: 89-92.
    • (1995) Neurosci Lett , vol.188 , pp. 89-92
    • Takayama, C.1    Nakagawa, S.2    Watanabe, M.3    Mishina, M.4    Inoue, Y.5
  • 61
    • 0031012268 scopus 로고    scopus 로고
    • Differential localization of delta glutamate receptors in the rat cerebellum: Coexpression with AMPA receptors in parallel fiber-spine synapses and absence from climbing fiber-spine synapses
    • Landsend AS, Amiry-Moghaddam M, Matsubara A, et al. Differential localization of delta glutamate receptors in the rat cerebellum: coexpression with AMPA receptors in parallel fiber-spine synapses and absence from climbing fiber-spine synapses. J Neurosci 1997; 17: 834-842.
    • (1997) J Neurosci , vol.17 , pp. 834-842
    • Landsend, A.S.1    Amiry-Moghaddam, M.2    Matsubara, A.3
  • 62
    • 0028173157 scopus 로고
    • Involvement of the glutamate receptor delta 2 subunit in the long-term depression of glutamate responsiveness in cultured rat Purkinje cells
    • Hirano T, Kasono K, Araki K, Shinozuka K, Mishina M. Involvement of the glutamate receptor delta 2 subunit in the long-term depression of glutamate responsiveness in cultured rat Purkinje cells. Neurosci Lett 1994; 182: 172-176.
    • (1994) Neurosci Lett , vol.182 , pp. 172-176
    • Hirano, T.1    Kasono, K.2    Araki, K.3    Shinozuka, K.4    Mishina, M.5
  • 63
    • 0029973629 scopus 로고    scopus 로고
    • Suppression of the glutamate receptor delta 2 subunit produces a specific impairment in cerebellar long-term depression
    • Jeromin A, Huganir RL, Linden DJ. Suppression of the glutamate receptor delta 2 subunit produces a specific impairment in cerebellar long-term depression. J Neurophysiol 1996; 76: 3578-3583.
    • (1996) J Neurophysiol , vol.76 , pp. 3578-3583
    • Jeromin, A.1    Huganir, R.L.2    Linden, D.J.3
  • 64
    • 0028799717 scopus 로고
    • Suppression of LTD in cultured Purkinje cells deficient in the glutamate receptor delta 2 subunit
    • Hirano T, Kasono K, Araki K, Mishina M. Suppression of LTD in cultured Purkinje cells deficient in the glutamate receptor delta 2 subunit. NeuroReport 1995; 6: 524-526.
    • (1995) NeuroReport , vol.6 , pp. 524-526
    • Hirano, T.1    Kasono, K.2    Araki, K.3    Mishina, M.4
  • 65
    • 0029023325 scopus 로고
    • Impairment of motor coordination, Purkinje cell synapse formation, and cerebellar long-term depression in GluR delta 2 mutant mice
    • Kashiwabuchi N, Ikeda K, Araki K, et al. Impairment of motor coordination, Purkinje cell synapse formation, and cerebellar long-term depression in GluR delta 2 mutant mice. Cell 1995; 81: 245-252.
    • (1995) Cell , vol.81 , pp. 245-252
    • Kashiwabuchi, N.1    Ikeda, K.2    Araki, K.3
  • 66
    • 0035062556 scopus 로고    scopus 로고
    • Classical eyeblink conditioning in glutamate receptor subunit delta2 mutant mice is impaired in the delay paradigm but not in the trace paradigm
    • Kishimoto Y, Kawahara S, Suzuki M, et al. Classical eyeblink conditioning in glutamate receptor subunit delta2 mutant mice is impaired in the delay paradigm but not in the trace paradigm. Eur J Neurosci 2001; 13: 1249-1253.
    • (2001) Eur J Neurosci , vol.13 , pp. 1249-1253
    • Kishimoto, Y.1    Kawahara, S.2    Suzuki, M.3
  • 67
    • 0031439985 scopus 로고    scopus 로고
    • Impaired parallel fiber-Purkinje cell synapse stabilization during cerebellar development of mutant mice lacking the glutamate receptor delta2 subunit
    • Kurihara H, Hashimoto K, Kano M, et al. Impaired parallel fiber-Purkinje cell synapse stabilization during cerebellar development of mutant mice lacking the glutamate receptor delta2 subunit. J Neurosci 1997; 17: 9613-9623.
    • (1997) J Neurosci , vol.17 , pp. 9613-9623
    • Kurihara, H.1    Hashimoto, K.2    Kano, M.3
  • 68
    • 0019888362 scopus 로고
    • Bacteriophage P1 site-specific recombination. I. Recombination between loxP sites
    • Sternberg N, Hamilton D. Bacteriophage P1 site-specific recombination. I. Recombination between loxP sites. J Mol Biol 1981; 150: 467-486.
    • (1981) J Mol Biol , vol.150 , pp. 467-486
    • Sternberg, N.1    Hamilton, D.2
  • 69
    • 0029959207 scopus 로고    scopus 로고
    • Conditional gene targeting
    • Rajewsky K, Gu H, Kuhn R, et al. Conditional gene targeting. J Clin Invest 1996; 98: 600-603.
    • (1996) J Clin Invest , vol.98 , pp. 600-603
    • Rajewsky, K.1    Gu, H.2    Kuhn, R.3
  • 70
    • 0033644144 scopus 로고    scopus 로고
    • Conditional gene knockout using ere recombinase
    • Le Y, Sauer B. Conditional gene knockout using ere recombinase. Methods Mol Biol 2000; 136: 477-485.
    • (2000) Methods Mol Biol , vol.136 , pp. 477-485
    • Le, Y.1    Sauer, B.2
  • 71
    • 0034489127 scopus 로고    scopus 로고
    • Cre recombinase expression in cerebellar Purkinje cells
    • Barski JJ, Dethleffsen K, Meyer M. Cre recombinase expression in cerebellar Purkinje cells. Genesis 2000; 28: 93-98.
    • (2000) Genesis , vol.28 , pp. 93-98
    • Barski, J.J.1    Dethleffsen, K.2    Meyer, M.3
  • 72
    • 0032923739 scopus 로고    scopus 로고
    • Generalized lacZ expression with the ROSA26 Cre reporter strain
    • Soriano P. Generalized lacZ expression with the ROSA26 Cre reporter strain. Nat Genet 1999; 21: 70-71.
    • (1999) Nat Genet , vol.21 , pp. 70-71
    • Soriano, P.1
  • 73
    • 0030845382 scopus 로고    scopus 로고
    • Cre-mediated somatic site-specific recombination in mice
    • Akagi K, Sandig V, Vooijs M, et al. Cre-mediated somatic site-specific recombination in mice. Nucleic Acid Res 1997; 25: 1766-1773.
    • (1997) Nucleic Acid Res , vol.25 , pp. 1766-1773
    • Akagi, K.1    Sandig, V.2    Vooijs, M.3
  • 74
    • 0033534701 scopus 로고    scopus 로고
    • Inducible site-specific recombination in the brain
    • Kellendonk C, Troche F, Casanova E, et al. Inducible site-specific recombination in the brain. J Mol Biol 1999; 285: 175-182.
    • (1999) J Mol Biol , vol.285 , pp. 175-182
    • Kellendonk, C.1    Troche, F.2    Casanova, E.3
  • 75
    • 0034805524 scopus 로고    scopus 로고
    • Purkinje cell-specific and inducible gene recombination system generated from c57b1/6 mouse ES cells
    • Kitayama K, Abe M, Kakizaki T, et al. Purkinje cell-specific and inducible gene recombination system generated from c57b1/6 mouse ES cells. Biochem Biophys Res Commun 2001; 281: 1134-1140.
    • (2001) Biochem Biophys Res Commun , vol.281 , pp. 1134-1140
    • Kitayama, K.1    Abe, M.2    Kakizaki, T.3
  • 76
    • 0029874029 scopus 로고    scopus 로고
    • Regulation of Cre recombinase activity by the synthetic steroid RU 486
    • Kellendonk C, Tronche F, Monaghan AP, et al. Regulation of Cre recombinase activity by the synthetic steroid RU 486. Nucleic Acids Res 1996; 24: 1404-1411.
    • (1996) Nucleic Acids Res , vol.24 , pp. 1404-1411
    • Kellendonk, C.1    Tronche, F.2    Monaghan, A.P.3
  • 77
    • 0028928854 scopus 로고
    • Site-specific recombination of a transgene in fertilized eggs by transient expression of Cre recombinase
    • Araki K, Araki M, Miyazaki J, Vassalli P. Site-specific recombination of a transgene in fertilized eggs by transient expression of Cre recombinase. Proc Natl Acad Sci USA 1995; 92: 160-164.
    • (1995) Proc Natl Acad Sci USA , vol.92 , pp. 160-164
    • Araki, K.1    Araki, M.2    Miyazaki, J.3    Vassalli, P.4
  • 78
    • 0033150274 scopus 로고    scopus 로고
    • Internal ribosome entry sites (IRESs): Reality and use
    • Houdebine LM, Attal J. Internal ribosome entry sites (IRESs): reality and use. Transgenic Res 1999; 8: 157-177.
    • (1999) Transgenic Res , vol.8 , pp. 157-177
    • Houdebine, L.M.1    Attal, J.2
  • 79
    • 0033499890 scopus 로고    scopus 로고
    • Cerebellar granule cell-specific and inducible expression of Cre recombinase in the mouse
    • Tsujita M, Mori H, Watanabe M, et al. Cerebellar granule cell-specific and inducible expression of Cre recombinase in the mouse. J Neurosci 1999; 19: 10318-10323.
    • (1999) J Neurosci , vol.19 , pp. 10318-10323
    • Tsujita, M.1    Mori, H.2    Watanabe, M.3
  • 80
    • 0031874849 scopus 로고    scopus 로고
    • Improved properties of FLP recombinase evolved by cycling mutagenesis
    • Buchholz F, Angrand PO, Stewart AF. Improved properties of FLP recombinase evolved by cycling mutagenesis. Nat Biotechnol 1998; 16: 657-662.
    • (1998) Nat Biotechnol , vol.16 , pp. 657-662
    • Buchholz, F.1    Angrand, P.O.2    Stewart, A.F.3
  • 81
    • 0031439662 scopus 로고    scopus 로고
    • Isoform specificity in the relationship of actin to dendritic spines
    • Kaech S, Fischer M, Doll T, Matus A. Isoform specificity in the relationship of actin to dendritic spines. J Neurosci 1997; 17: 9565-9572.
    • (1997) J Neurosci , vol.17 , pp. 9565-9572
    • Kaech, S.1    Fischer, M.2    Doll, T.3    Matus, A.4
  • 82
    • 0030816323 scopus 로고    scopus 로고
    • Synaptopodin: An actin-associated protein in telencephalic dendrites and renal podocytes
    • Mundel P, Heid HW, Mundel TM, et al. Synaptopodin: an actin-associated protein in telencephalic dendrites and renal podocytes. J Cell Biol 1997; 139: 193-204.
    • (1997) J Cell Biol , vol.139 , pp. 193-204
    • Mundel, P.1    Heid, H.W.2    Mundel, T.M.3
  • 83
    • 0032191909 scopus 로고    scopus 로고
    • Synaptic activation causes the mRNA for the IEG Arc to localize selectively near activated postsynaptic sites on dendrites
    • Steward O, Wallace CS, Lyford GL, Worley PF. Synaptic activation causes the mRNA for the IEG Arc to localize selectively near activated postsynaptic sites on dendrites. Neuron 1998; 21: 741-751.
    • (1998) Neuron , vol.21 , pp. 741-751
    • Steward, O.1    Wallace, C.S.2    Lyford, G.L.3    Worley, P.F.4


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