Conversion of the catalytic specificity of alanine racemase to a D-amino acid aminotransferase activity by a double active-site mutation

Journal of Molecular Catalysis B: Enzymatic

Volumn 23, Issue 2-6, 2003, Pages 311-319

  Yow, Geok Yong ^a   Watanabe, Akira ^a   Yoshimura, Tohru ^a   Esaki, Nobuyoshi ^a  

^a KYOTO UNIVERSITY   (Japan)

Author keywords

Alanine racemase; D Amino acid aminotransferase; Protein engineering; Pyridoxal 5 phosphate; Transamination

Indexed keywords

AMINO ACIDS; BACTERIA; ENZYMES; NITROGEN;

RACEMIZATION;

CATALYSIS;

ALANINE; ALANINE RACEMASE; AMINOTRANSFERASE; ARGININE; ASPARTIC ACID; DEXTRO ALANINE; GLUTAMIC ACID; PYRIDINIUM DERIVATIVE; TYROSINE;

ARTICLE; CATALYSIS; ENZYME ACTIVE SITE; ENZYME ACTIVITY; ENZYME SPECIFICITY; ENZYME SUBSTRATE; GEOBACILLUS STEAROTHERMOPHILUS; MOLECULAR INTERACTION; MUTATION; TRANSAMINATION;

GEOBACILLUS STEAROTHERMOPHILUS;

EID: 0041431075     PISSN: 13811177     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1381-1177(03)00094-8     Document Type: Article

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