Occurrence and regulation of the multicellular morphotype in Salmonella serovars important in human disease

International Journal of Medical Microbiology

Volumn 293, Issue 4, 2003, Pages 273-285

  Römling, Ute ^a,b   Bokranz, Werner ^b   Rabsch, Wolfgang ^c   Zogaj, Xhavit ^a   Nimtz, Manfred ^b   Tschäpe, Helmut ^c  

^a KAROLINSKA INSTITUTE   (Sweden)

^b HELMHOLTZ CENTRE FOR INFECTION RESEARCH   (Germany)

^c ROBERT KOCH INSTITUTE   (Germany)

Author keywords

Biofilm; Cellulose; Curli fimbriae; ompR; rpoS; Thin aggregative fimbriae

Indexed keywords

BACTERIAL PROTEIN; CELLULOSE; OUTER MEMBRANE PROTEIN REGULATOR; PROTEIN CSGD; PROTEIN RDAR; SIGMA FACTOR RPOS; UNCLASSIFIED DRUG;

ARTICLE; BACTERIAL INFECTION; BACTERIAL STRAIN; BACTERIOPHAGE; BIOFILM; EXTRACELLULAR MATRIX; FIMBRIA; HUMAN; INTESTINE EPITHELIUM CELL; PHENOTYPE; PROTEIN EXPRESSION; PROTEIN PROTEIN INTERACTION; SALMONELLA TYPHIMURIUM; TEMPERATURE DEPENDENCE;

SALMONELLA; SALMONELLA CHOLERAESUIS; SALMONELLA ENTERITIDIS; SALMONELLA GALLINARUM; SALMONELLA TYPHI; SALMONELLA TYPHIMURIUM;

EID: 0041424877     PISSN: 14384221     EISSN: None     Source Type: Journal    
DOI: 10.1078/1438-4221-00268     Document Type: Article

References (36)

1. Ausmees, N., Jonsson, H., Hoglund, S., Ljunggren, H., Lindberg, M.: Structural and putative regulatory genes involved in cellulose synthesis in Rhizobium leguminosarum bv. trifolii. Microbiology. 145, 1253-1262 (1999).
2. Austin, J. W., Sanders, G., Kay, W. W., Collinson, S. K.: Thin aggregative fimbriae enhance Salmonella enteritidis biofilm formation. FEMS Microbiol. Lett. 162, 295-301 (1998).
3. Ausubel, F. M., Brent, R., Kingston, R. E., Moore, D. D., Seidman, J. G., Smith, J. A., Struhl, K.: Current Protocols in Molecular Biology. John Wiley & Sons, Washington, DC 1994.
4. Baumler, A. J., Gilde, A. J., Tsolis, R. M., van der Velden, A. W., Ahmer, B. M., Heffron, F.: Contribution of horizontal gene transfer and deletion events to development of distinctive patterns of fimbrial operons during evolution of Salmonella serotypes. J. Bacteriol. 179, 317-322 (1997).
5. Bian, Z., Brauner, A., Li, Y., Normark, S.: Expression of and cytokine activation by Escherichia coli curli fibers in human sepsis. J. Infect. Dis. 181, 602-612 (2000).
6. rd: MlrA, a novel regulator of curli (AgF) and extracellular matrix synthesis by Escherichia coli and Salmonella enterica serovar Typhimurium. Mol. Microbiol. 41, 349-363 (2001).
7. Chapman, M. R., Robinson, L. S., Pinkner, J. S., Roth, R., Heuser, J., Hammar, M., Normark, S., Hultgren, S. J.: Role of Escherichia coli curli operons in directing amyloid fiber formation. Science 295, 851-855 (2002).
8. Collinson, S. K., Parker, J. M., Hodges, R. S., Kay, W. W.: Structural predictions of AgfA, the insoluble fimbrial subunit of Salmonella thin aggregative fimbriae. J. Mol. Biol. 290, 741-756 (1999).
9. Dibb-Fuller, M. P., Allen-Vercoe, E., Thorns, C. J., Woodward, M. J.: Fimbriae- and flagella-mediated association with and invasion of cultured epithelial cells by Salmonella enteritidis. Microbiology 145 (Pt 5), 1023-1031 (1999).
10. Doran, J. L., Collinson, S. K., Burian, J., Sarlos, G., Todd, E. C., Munro, C. K., Kay, C. M., Banser, P. A., Peterkin, P. I., Kay, W. W.: DNA-based diagnostic tests for Salmonella species targeting agfA, the structural gene for thin, aggregative fimbriae. J. Clin. Microbiol. 31, 2263-2273 (1993).
11. Dorel, C., Vidal, O., Prigent-Combaret, C., Vallet, I., Lejeune, P.: Involvement of the Cpx signal transduction pathway of E. coli in biofilm formation. FEMS Microbiol. Lett. 178, 169-175 (1999).
12. Gerstel, U., Römling, U.: Oxygen tension and nutrient starvation are major signals that regulate agfD promoter activity and expression of the multicellular morphotype in Salmonella typhimurium. Environ Microbiol. 3, 638-648 (2001).
13. Gophna, U., Barlev, M., Seijffers, R., Oelschlager, T. A., Hacker, J., Ron, E. Z.: Curli fibers mediate internalization of Escherichia coli by eukaryotic cells. Infect. Immun. 69, 2659-2665 (2001).
14. Hammar, M., Arnqvist, A., Bian, Z., Olsen, A., Normark, S.: Expression of two csg operons is required for production of fibronectin- and congo red-binding curli polymers in Escherichia coli K-12. Mol. Microbiol. 18, 661-670 (1995).
15. Mahan, M. J., Slauch, J. M., Mekalanos, J. J.: Environmental regulation of virulence gene expression in Escherichia, Salmonella, and Shigella spp. In: Escherichia coli and Salmonella: Cellular and Molecular Biology, Vol. 2 (Umbarger, H. E., ed.), pp. 2256-2276. American Society for Microbiology, Washington, DC 1996.
16. Maloy, S., Stewart, V. J., Taylor, R. K.: Genetic analysis of pathogenic bacteria. Cold Spring Harbor Laboratory Press, Cold Spring Harbor, NY 1996.
17. Ohl, M. E., Miller, S. I.: Salmonella: a model for bacterial pathogenesis. Annu. Rev. Med. 52, 259-274 (2001).
18. Olsen, A., Jonsson, A., Normark, S.: Fibronectin binding mediated by a novel class of surface organelles on Escherichia coli. Nature 338, 652-655 (1989).
19. Olsen, A., Arnqvist, A., Hammar, M., Sukupolvi, S., Normark, S.: The RpoS sigma factor relieves H-NS-mediated transcriptional repression of csgA, the subunit gene of fibronectin-binding curli in Escherichia coli. Mol. Microbiol. 7, 523-536 (1993).
20. Parkhill, J., Dougan, G., James, K. D., Thomson, N. R., Pickard, D., Wain, J., Churcher, C., Mungall, K. L., Bentley, S. D., Holden, M. T., Sebaihia, M., Baker, S., Basham, D., Brooks, K., Chillingworth, T., Connerton, P., Cronin, A., Davis, P., Davies, R. M., Dowd, L., White, N., Farrar, J., Feltwell, T., Hamlin, N., Haque, A., Hien, T. T., Holroyd, S., Jagels, K., Krogh, A., Larsen, T. S., Leather, S., Moule, S., O'Gaora, P., Parry, C., Quail, M., Rutherford, K., Simmonds, M., Skelton, J., Stevens, K., Whitehead, S., Barrell, B. G.: Complete genome sequence of a multiple drug resistant Salmonella enterica serovar Typhi CT18. Nature 413, 848-852 (2001).
21. Prigent-Combaret, C., Brombacher, E., Vidal, O., Ambert, A., Lejeune, P., Landini, P., Dorel, C.: Complex regulatory network controls initial adhesion and biofilm formation in Escherichia coli via regulation of the csgD gene. J. Bacteriol. 183, 7213-7223 (2001).
22. Rabsch, W., Andrews, H. L., Kingsley, R. A., Prager, R., Tschäpe, H., Adams, L. G., Baumler, A. J.: Salmonella enterica serotype Typhimurium and its host-adapted variants. Infect. Immun. 70, 2249-2255 (2002).
23. Rajashekara, G., Munir, S., Alexeyev, M. F., Halvorson, D. A., Wells, C. L., Nagaraja, K. V.: Pathogenic role of SEF14, SEF17, and SEF21 fimbriae in Salmonella enterica serovar enteritidis infection of chickens. Appl. Environ. Microbiol. 66, 1759-1763 (2000).
24. Römling, U., Bian, Z., Hammar, M., Sierralta, W. D., Normark, S.: Curli fibers are highly conserved between Salmonella typhimurium and Escherichia coli with respect to operon structure and regulation. J. Bacteriol. 180, 722-731 (1998a).
25. Römling, U., Sierralta, W. D., Eriksson, K., Normark, S.: Multicellular and aggregative behaviour of Salmonella typhimurium strains is controlled by mutations in the agfD promoter. Mol. Microbiol. 28, 249-264 (1998b).
26. Römling, U., Rohde, M., Olsen, A., Normark, S., Reinkoster, J.: AgfD, the checkpoint of multicellular and aggregative behaviour in Salmonella typhimurium regulates at least two independent pathways. Mol. Microbiol. 36, 10-23 (2000).
27. Sakellaris, H., Hannink, N. K., Rajakumar, K., Bulach, D., Hunt, M., Sasakawa, C., Adler, B.: Curli loci of Shigella spp. Infect. Immun. 68, 3780-3783 (2000).
28. Solano, C., Garcia, B., Valle, J., Berasain, C., Ghigo, J. M., Gamazo, C., Lasa, I.: Genetic analysis of Salmonella enteritidis biofilm formation: critical role of cellulose. Mol. Microbiol. 43, 793-808 (2002).
29. Sukupolvi, S., Lorenz, R. G., Gordon, J. I., Bian, Z., Pfeifer, J. D., Normark, S. J., Rhen, M.: Expression of thin aggregative fimbriae promotes interaction of Salmonella typhimurium SR-11 with mouse small intestinal epithelial cells. Infect. Immun. 65, 5320-5325 (1997).
30. Uhlich, G. A., Keen, J. E., Elder, R. O.: Variations in the csgD promoter of Escherichia coli O157:H7 associated with increased virulence in mice and increased invasion of HEp-2 cells. Infect. Immun. 70, 395-399 (2002).
31. Updegraff, D. M.: Semimicro determination of cellulose in biological materials. Anal Biochem. 32, 420-424 (1969).
32. Walker, K. A., Atkins, C. L., Osuna, R.: Functional determinants of the Escherichia coli fis promoter: roles of -35, -10, and transcription initiation regions in the response to stringent control and growth phase-dependent regulation. J. Bacteriol. 181, 1269-1280 (1999).
33. van der Velden, A. W., Baumler, A. J., Tsolis, R. M., Heffron, F.: Multiple fimbrial adhesins are required for full virulence of Salmonella typhimurium in mice. Infect. Immun. 66, 2803-2808 (1998).
34. Vazquez-Torres, A., Fang, F. C.: Cellular routes of invasion by enteropathogens. Curr. Opin. Microbiol. 3, 54-59 (2000).
35. Wilcock, P. B., Schwarz, K. J.: Salmonellosis. In: Diseases of Swine (A. D. Leman, B. E. Straw, W. E. Mengeling, S. D'Allaire, D. J. Taylor, eds.), pp. 570-583. Iowa State University Press, Iowa 1992.
36. Zogaj, X., Nimtz, M., Rohde, M., Bokranz, W., Römling, U.: The multicellular morphotypes of Salmonella typhimurium and Escherichia coli produce cellulose as the second component of the extracellular matrix. Mol. Microbiol. 39, 1452-1463 (2001).