The effect of S-nitrosoglutathione on insulin receptor behavior on erythrocytes in an animal model

Diabetologia Croatica

Volumn 32, Issue 2, 2003, Pages 65-71

  McGrowder, Donovan ^a   Ragoobirsingh, Dalip ^a   Dasgupta, Tara ^a  

^a UNIVERSITY OF THE WEST INDIES   (Jamaica)

Author keywords

Average receptor affinity; Erythrocytes; Insulin receptor sites per cell; Nitric oxide; S nitrosoglutathione

Indexed keywords

CAPTOPRIL; INSULIN; INSULIN RECEPTOR; NITRIC OXIDE; NITRIC OXIDE DONOR; S NITROSOGLUTATHIONE;

ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; BINDING SITE; BLOOD SAMPLING; CELL FUNCTION; COMPETITIVE INHIBITION; CONCENTRATION RESPONSE; CONTROLLED STUDY; DIABETES MELLITUS; DIABETOGENESIS; DOG; ERYTHROCYTE; ERYTHROCYTE MEMBRANE; FEMALE; HORMONE RECEPTOR INTERACTION; IMPAIRED GLUCOSE TOLERANCE; INSULIN BINDING; MALE; NONHUMAN; ORAL GLUCOSE TOLERANCE TEST; PATHOPHYSIOLOGY; PROTEIN EXPRESSION; RECEPTOR AFFINITY; RECEPTOR DENSITY; REGULATORY MECHANISM;

EID: 0041423679     PISSN: 03510042     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (23)

1. Moncada S, Palmer RMJ, Higgs, EA. Nitric oxide: physiology, pathophysiology, and pharmacology. Pharmacol Rev 1991;143:109-142.
2. Burkart V, Kroncke KD, Brenner HH, Kolb H, Kolb-Bachofen V. Nitric oxide is a pathogenetic factor in type 1 diabetes. Diabetologia 1991;34 (Suppl 2):A95. (abstract)
3. Stamler JS, Jaraki O, Osbourne JA, Simon DI, Keany J, Vita J, Singh D, Valeri DC, Loscalzo J. Nitric oxide circulates in mammalian plasma primarily as an S-nitroso-adduct of serum albumin. Proc Natl Acad Sci USA 1992; 89:7674-7677.
4. Ignarro LJ, Lippton H, Edwards JC, Baricos WH, Hyman AL, Kadowitz PJ, Greutter CA. Mechanism of vascular smooth muscle relaxation by organic nitrates, nitroprusside and nitric oxide: evidence for the involvement of s-nitrosothiols as active intermediates. J Pharmacol Exp Ther 1981;218:739-749.
5. Konorev EA, Tarpey MM, Joseph J, Baker JE, Kalyanaraman BJ. S-nitrosoglutathione improves functional recovery in the isolated rat heart after cardioplegic ischemic arrest - evidence for a cardioprotective effect of nitric oxide. J Pharmacol Exp Ther 1995;274:200-206.
6. Macallister RJ, Calver AL, Riezebos J, Collier J, Vallance P. Relative potency and arteriovenous selectivity of nitrovasodilators on human blood vessels: an insight into targeting of nitric oxide delivery. J Pharmacol Exp Ther 1995;273:154-160.
7. Langford EJ, Brown AS, Wainwright RJ, De Belder AJ, Thomas MR, Smith REA, Radomski MW, Martin JF, Moncada S. Inhibition of platelet activity by S-nitrosoglutathione during coronary angioplasty. Lancet 1994;344:1458-1460.
8. McGrowder D, Ragoobirsingh D, Dasgupta T. The hyperglycemic effect of S-nitrosoglutathione in the dog. Nitric Oxide 1999;3:481-491.
9. Gorden P. Hormone receptor interactions. Diabetes 1979;28:8.
10. Khan C, Goldfine R, Neville DM, DeMeyts P. Alterations in insulin binding induced by changes in vivo in the levels of glucocorticoids and growth hormone. Endocrinology 1978;103:1054-1066.
11. Hart W. Some observations concerning the S-nitroso and S-phenylsulphonyl derivatives of L-cysteine and glutathione. Tetrahedron Lett 1985;26:2013-2016.
12. Ghambir KK, Archer JA, Bradley CJ. Characteristics of human erythrocyte insulin receptors. Diabetes 1978;27:701-708.
13. Scatchard G. The attraction of proteins for small molecules and ions. Ann NY Acad Sci 1949;51:660-672.
14. DeMeyts P, Roth J, Neville DM, Jr, Gavin JR, Lesniak MA. Insulin's interactions with its receptors - experimental evidence for negative cooperativity. Biochem Biophys Res Commun 1973;55:154-165.
15. LeFloch J-P, Escuyer P, Baudin E, Baudon D, Perlemuter L. Blood glucose area under the curve: methodological aspects. Diabetes Care 1990;13:172-175.
16. Godfrey K. Statistics in practice: comparing the means of several groups. N Engl J Med 1985;313:1450-1456.
17. Segal SS. Nitric oxide release is present from incubated skeletal muscle preparations (Editorial). J Appl Physiol 1994;77:2517-2518.
18. Kasuga M, Zick Y, Blithe DL, Crettaz M, Khan CR. Insulin stimulates tyrosine phosphorylation of the insulin receptor in a "cell-free" system. Nature 1982;298:667-669.
19. Harmon JT, Khan CR, Kempner ES, Schlegel W. Characterization of the insulin receptor in its membrane environment by radiation inactivation. J Biol Chem 1980;255:3412-3419.
20. Massague J, Czech MP. Role of disulphides in the sub-unit structure of the insulin receptor. J Biol Chem 1982;257:6729-6738.
21. Slater TF. Free radical mechanisms in tissue injury. Biochem J 1984;22:1-15.
22. Dons RF, Corash LM, Gorden P. The insulin receptor is an age-dependent integral component of the human erythrocyte membrane. J Biol Chem 1981;256:2982-2987.
23. Soll AH, Golfin ID, Roth J, Kahn CR. Impairment of insulin binding to the fat cell membranes in the obese hyperglycemic mouse. FEBS Lett 1972;25:339-342.