Association between plasminogen activator inhibitor 1 gene polymorphisms and preeclampsia

Gynecologic and Obstetric Investigation

Volumn 56, Issue 1, 2003, Pages 17-22

  Fabbro, Dora ^a   D'Elia, Angela V ^a   Spizzo, Riccardo ^a   Driul, Lorenza ^a   Barillari, Giovanni ^b   Di Loreto, Carla ^a   Marchesoni, Diego ^a   Damante, Giuseppe ^a  

^a UNIVERSITY OF UDINE   (Italy)

^b UNIVERSITY HOSPITAL OF UDINE   (Italy)

Author keywords

Gene polymorphisms; PAI 1; Preeclampsia

Indexed keywords

BLOOD CLOTTING FACTOR 5; BLOOD CLOTTING FACTOR 5 LEIDEN; PLASMINOGEN ACTIVATOR INHIBITOR 1; PROTHROMBIN;

ADULT; ARTICLE; BLOOD; CONTROLLED STUDY; DISEASE ASSOCIATION; DISEASE SEVERITY; DNA EXTRACTION; DNA POLYMORPHISM; FEMALE; FIBRINOLYSIS; GENE; GENE CONTROL; GENE FREQUENCY; GENE IDENTIFICATION; GENE MUTATION; GENETIC TRANSCRIPTION; GENETIC VARIABILITY; GENOTYPE; HUMAN; MAJOR CLINICAL STUDY; PLASMINOGEN ACTIVATOR INHIBITOR 1 GENE; PREECLAMPSIA; PREGNANCY; PREVALENCE;

ADULT; ALLELES; FACTOR V; FEMALE; FIBRINOLYSIS; GENE FREQUENCY; GENOTYPE; HUMANS; IMMUNOHISTOCHEMISTRY; METHYLENETETRAHYDROFOLATE REDUCTASE (NADPH2); MUTATION; PLASMINOGEN ACTIVATOR INHIBITOR 1; POLYMORPHISM, GENETIC; PRE-ECLAMPSIA; PREGNANCY; PROTHROMBIN;

EID: 0041422248     PISSN: 03787346     EISSN: None     Source Type: Journal    
DOI: 10.1159/000072326     Document Type: Article

References (28)

1. Roberts JM, Taylor RN, Musci TJ, Rodgers GM, Hubel CA, McLaughlin MK: Preeclampsia: An endothelial cell disorder. Am J Obstet Gynecol 1989;161:1200-1204.
2. Khong TY, Pearce JM, Robertson WB: Acute atherosis in preeclampsia: Maternal determinants and fetal outcome in the presence of the lesion. Am J Obstet Gynecol 1987;157:360-363.
3. Many A, Schreiber L, Rosner S, Lessing JB, Eldor A, Kupferminc MJ: Pathologic features of the placenta in women with severe pregnancy complications and thrombophilia. Obstet Gynecol 2001;98:1041-1044.
4. American College of Obstetricians and Gynecologists. ACOG Pract Bull 2002;99:159-166.
5. van Beck E, Peeters LL: Pathogenesis of preeclampsia: A comprehensive model. Obstet Gynecol Surv 1998;53:233-239.
6. Ensom MH, Stephenson MD: Low-molecular-weight heparins in pregnancy. Pharmacotherapy 1999;19:1013-1025.
7. Roberts JM, Cooper DW: Pathogenesis and genetics of preeclampsia. Lancet 2001;357:53-56.
8. Kupferminc MJ, Eldor A, Steinman N, Many A, Bar-Am A, Jaffa A, Fait G, Lessing JB: Increased frequency of genetic thrombophilia in women with complications of pregnancy. N Engl J Med 1999;340:9-13.
9. Olds RJ, Fitches AC, Geary CP: The multigenic basis for venous thrombosis. Br J Haematol 2000;109:508-511.
10. Hellgren M: Hemostasis during pregnancy and puerperium. Haemostasis 1996;26(suppl 4):244-247.
11. D'Elia AV, Driul L, Giacomello R, Colaone R, Fabbro D, Di Leonardo C , Florio P, Petraglia F, Marchesoni D, Damante G: Frequency of factor V, prothrombin and methylenetetrahydrofolate reductase gene variants in preeclampsia. Gynecol Obstet Invest 2001;141:84-87.
12. Fareed J, Hoppensteadt DA, Jeske WP, Ahmad S, Bick RL: Acquired defects of fibrinolysis associated with thrombosis. Semin Thromb Hemost 1999;25:367-374.
13. Hong JJ, Kwaan HC: Hereditary defects in fibrinolysis associated with thrombosis. Semin Thromb Hemost 1999;25:321-331.
14. Estelles A, Gilabert J, Grancha S, Yamamoto K, Thinnes T, Espana F, Aznar J, Loskutoff DJ: Abnormal expression of type 1 plasminogen activator inhibitor and tissue factor in severe preeclampsia. Thromb Haemost 1998;79:500-508.
15. Gao M, Nakabayashi M, Sakura M, Takeda Y: The imbalance of plasminogen activators and inhibitors in preeclampsia. J Obstet Gynaecol Res 1996;22:9-16.
16. Eriksson P, Kallin B, van't Hooft FM, Bavenholm P, Hamsten A: Allele-specific increase in basal transcription of the plasminogen-activator inhibitor 1 gene is associated with myocardial infarction. Proc Natl Acad Sci U S A 1995;92:1851-1855.
17. Grubic N, Stegnar M, Peternel P, Kaider A, Binder BR: A novel G/A and the 4G/5G polymorphism within the promoter of the plasminogen activator inhibitor-1 gene in patients with deep vein thrombosis. Thromb Res 1996;84:431-443.
18. Morange PE, Henry M, Tregouet D, Granel B, Aillaud MF, Alessi MC, Juahan-Vague I: The A-844G polymorphism in the PAI-1 gene is associated with a higher risk of venous thrombosis in factor V Leiden carriers. Arterioscler Thromb Vasc Biol 2000;20:1387-1391.
19. Henry M, Chomiki N, Scarabin PY, Alessi MC, Peiretti F, Arveiler D, Ferrieres J, Evans A, Amouyel P, Poirier O, Cambien F, Juhan-Vague I: Five frequent polymorphisms of the PAI-1 gene. Arterioscler Tromb Vasc Biol 1997;17:851-858.
20. Glueck CJ, Kupferminc MJ, Fontaine RN, Wang P, Weksler BB, Eldor A: Genetic hypofibrinolysis in complicated pregnancies. Obstet Gynecol 2001;97:44-48.
21. Yamada N, Arinami T, Yamakawa-Kobayashi K, Watanabe H, Sohda S, Hamada H, Kubo T, Hamaguchi H: The 4G/5G polymorphism of the plasminogen activator inhibitor-1 gene is associated with severe preeclampsia. J Hum Genet 2000;45:138-141.
22. Odegard RA, Vatten LJ, Nilsen ST, Salvesen KA, Austgulen R: Risk factors and clinical manifestations of pre-eclampsia. BJOG 2000;107:1410-1416.
23. Morrison ER, Miedzybrodzka ZH, Campbell DM, Haites NE, Wilson BJ, Watson MS, Greaves M, Vickers MA: Prothrombotic genotypes are not associated with pre-eclampsia and gestational hypertension: Results from a large population-based study and systematic review. Thromb Haemost 2002;87:779-785.
24. Francis CW: Plasminogen activator inhibitor-1 levels and polymorphisms. Arch Pathol Lab Med 2002;126:1401-1404.
25. Kawasaki T, Dewerchin M, Lijnen HR, Vermylen J, Hoylaerts MF: Vascular release of plasminogen activator inhibitor-1 impairs fibrinolysis during acute arterial thrombosis in mice. Blood 2000;96:153-160.
26. Conrad KP, Benyo DF: Placental cytokines and the pathogenesis of preeclampsia. Am J Reprod Immunol 1997;37:240-249.
27. Dawson SJ, Wiman B, Hamsten A, Green F, Humphries S, Henney AM: The two allele sequences of a common polymorphism in the promoter of the plasminogen activator inhibitor-1 (PAI-1) gene respond differently to interleukin-1 in Hep G2 cells. J Biol Chem 1993;268:10739-10745.
28. Estelles A, Gilabert J, Keeton M, Eguchi Y, Aznar J, Grancha S, Espna F, Loskutoff DJ, Schleef RR: Altered expression of plasminogen activator inhibitor type 1 in placentas from pregnant women with preeclampsia and/or intrauterine fetal growth retardation. Blood 1994;84:143-150.