Staphylococcus aureus vaccine against mastitis in dairy cows, composition and evaluation of its immunogenicity in a mouse model

Veterinary Immunology and Immunopathology

Volumn 93, Issue 3-4, 2003, Pages 159-167

  Leitner, G ^a   Lubashevsky, E ^b   Trainin, Z ^b  

^a EXTENSION SERVICE   (Israel)

^b KIMRON VETERINARY INSTITUTE   (Israel)

Author keywords

Bovine; CBs; cfu; Colony forming units; Columbia broth supplement; I m; IFA; Incomplete Freund adjuvant; Intramuscular; Mastitis; Mouse model; PC; PI; Post challenge; Post inoculation; Post vaccination; PV; S. aureus; SC; Staphylococcus aureus; Vaccine

Indexed keywords

BACTERIUM ANTIBODY; BS 449; FREUND ADJUVANT; IMMUNOLOGICAL ADJUVANT; ISA 206; MASTIVAC I; STAPHYLOCOCCUS VACCINE; UNCLASSIFIED DRUG; VLVL 8407; ZO 3984;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIBODY DETECTION; ANTIBODY PRODUCTION; ANTIGENICITY; ARTICLE; BACTERIAL IMMUNITY; BACTERIAL STRAIN; BACTERIUM ISOLATION; CATTLE DISEASE; CONTROLLED STUDY; DISEASE MODEL; DRUG EFFICACY; EXPERIMENTAL INFECTION; FEMALE; IMMUNOGENICITY; MASTITIS; MOUSE; NONHUMAN; STAPHYLOCOCCUS AUREUS; VACCINATION; ANIMAL; ANIMAL DISEASE; BLOOD; CATTLE; IMMUNOLOGY; PATHOGENICITY; STAPHYLOCOCCUS INFECTION; VIRULENCE;

BOVINAE; STAPHYLOCOCCUS; STAPHYLOCOCCUS AUREUS;

ANIMALS; ANTIBODIES, BACTERIAL; CATTLE; DISEASE MODELS, ANIMAL; FEMALE; MASTITIS, BOVINE; MICE; STAPHYLOCOCCAL INFECTIONS; STAPHYLOCOCCAL VACCINES; STAPHYLOCOCCUS AUREUS; VIRULENCE;

EID: 0041408497     PISSN: 01652427     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0165-2427(03)00069-2     Document Type: Article

References (16)

1. Avery V.M., Gordon D.L. Antibacterial properties of breast milk: requirements for surface phagocytosis and chemiluminescence. Eur. J. Clin. Microbiol. Infect. Dis. 10:1991;1034-1039.
2. Laemli U.K. Nature. 227:1970;680-685.
3. Leitner G., Krifucks O., Glickman A., Younis A., Saran A. Staphylococcus aureus strains isolated from bovine mastitis: virulence, antibody production and protection from challenge in a mouse model. FEMS Immunol. Med. Microbiol. 1476(35):2003;99-106.
4. Leitner G., Yadlin B., Glickman A., Chaffer M., Saran A. Systemic and local immune response of cows to intramammary infection with Staphylococcus aureus. Res. Vet. Sci. 69:2000;181-184.
5. Miller R.H., Guidry A.J., Paape M.J., Dulin A.M., Fulton L.A. Relationship between immunoglobulin concentrations in milk and phagocytosis by bovine neutrophils. Am. J. Vet. Res. 49:1988;42-45.
6. Nordhaug M.L., Nesse L.L., Norcross N.L., Gudding R. A field trial with an experimental vaccine against Staphylococcus aureus mastitis in cattle. I. Clinical parameters. J. Dairy Sci. 77:1994;1267-1275.
7. Pankey J.W., Boddie N.T., Watts J.L., Nickerson S.C. Evaluation of protein A and a commercial bacterin as vaccines against Staphylococcus aureus mastitis by experimental challenge. J. Dairy Sci. 68:1985;726-731.
8. SAS Institute, 2000. JMP Statistics and Graphics guide, Version 4. SAS Institute Inc., Cary, NC.
9. Watson D.L. Evaluation of attenuated, live staphylococcal mastitis vaccine in lactating heifers. J. Dairy Sci. 67:1984;2608-2613.
10. Watson E.D. Specific antibody in milk whey and phagocytosis of Actinomyces pyogenes by neutrophils in vitro. Res. Vet. Sci. 47:1989;253-256.
11. Watson D.L. Vaccination against experimental staphylococcal mastitis in dairy heifers. Res. Vet. Sci. 53:1992;346-353.
12. Watson, D.L., Schwartzkoff, C.L., 1990. A field trial to test the efficacy of a staphylococcal mastitis vaccine in commercial dairies in Australia. In: Proceedings of the International Symposium on Bovine Mastitis, National Mastitis Council, Arlington, pp. 73-76.
13. Watson D.L., McColl M.L., Davies H.I. Field trial of a staphylococcal mastitis vaccine in dairy heifers: clinical, subclinical and microbiological assessments. Aust. Vet. J. 74:1996;447-450.
14. Yoshida K., Ichiman Y., Narikawa S., Evans G.B. Staphylococcal capsular for preventing mastitis in two herds in Georgia. J. Dairy Sci. 67:1984;620-627.
15. Younis A., Leitner G., Heller E.D., Samra Z., Gadba R., Lubashevsky E., Chaffer M., Yadlin N., Winkler M., Saran A. Phenotypic characteristics of Staphylococcus aureus isolated from bovine mastitis in Israeli dairy herds. J. Vet. Med. B. 47:2000;591-597.
16. Ziv, G., 1995. Treatment of mastitis: an overview of progress during the last ten years. In: Proceedings of the Third IDF International Mastitis Seminar, vol. 5, Tel Aviv, Israel, pp. 3-12.