Urinary excretion of pyridinium cross-links and serum osteocalcin levels in patients with primary high-grade osteosarcoma

Calcified Tissue International

Volumn 73, Issue 1, 2003, Pages 1-4

  Ferrari, S ^a   Zolezzi, C ^a   Pratelli, L ^a   Fasano, M C ^a   Bacci, G ^a  

^a RIZZOLI ORTHOPAEDIC INSTITUTE   (Italy)

Author keywords

Alkaline phosphatase; Osteocalcin; Osteosarcoma; Pyridinium crosslinks

Indexed keywords

ALKALINE PHOSPHATASE; OSTEOCALCIN; PYRIDINIUM DERIVATIVE;

ADULT; ARTICLE; BONE TURNOVER; CHILD; CLINICAL ARTICLE; FEMALE; HUMAN; MALE; OSTEOSARCOMA; PRIORITY JOURNAL; PROGNOSIS; PROTEIN CROSS LINKING; URINALYSIS;

ADOLESCENT; ADULT; ALKALINE PHOSPHATASE; AMINO ACIDS; BONE NEOPLASMS; CHILD; FEMALE; HUMANS; MALE; NEOPLASM RECURRENCE, LOCAL; OSTEOCALCIN; OSTEOSARCOMA;

EID: 0041386374     PISSN: 0171967X     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00223-002-1046-1     Document Type: Article

References (14)

1. Campanacci M (1999) High grade osteosarcomas. In: Campanacci M (ed) Bone and soft tissue tumors. Springer-Verlag, Wien-New York, p 463
2. Kanis JA, McCloskey EV (1997) Bone turnover and biochemical markers in malignancy. Cancer 80(S):1538-1545
3. Demers LM, Costa L, Chinchilli VM, Gaydos L, Curley E, Lipton A (1995) Biochemical markers of bone turnover in patients with metastatic bone disease. Clin Chem 41:1489-1494
4. Seibel MJ, Duncan A, Robins SP (1989) Urinary hydroxypyridinium crosslinks provide indices of cartilage and bone involvement in arthritic diseases. J Rheumatol 16:964-970
5. Delmas PD, Schlemmer A, Gineyts E, Riis B, Christiansen C (1991) Urinary excretion of pyridinoline crosslinks correlates with bone turnover measured on iliac crest biopsy in patients with vertebral osteoporosis. J Bone Miner Res 6:639-644
6. Brown JP, Delmas PD, Malaval L, Edouard C, Chapuy PJM, Meunier PJM (1984) Serum bone Gla protein: a specific marker for bone formation in postmenopausal osteoporosis. Lancet I:1091-1093
7. Gobel V, Jurgens H, Etspuler G (1987) Prognostic significance of tumor volume in localized Ewing's sarcoma of bone in children and adolescents. J Cancer Res Clin Oncol 113:187-191
8. Uebelhart D, Gineyts E, Chapuy MC, Delmas PD (1990) Urinary excretion of pyridinium crosslinks: a new marker of bone resorption in metabolic bone disease. Bone Miner 8:87-96
9. Berruti A, Dogliotti L, Gorzegno G, Torta M, Tampellini M, Tucci M, Cerutti S, Mosca Frezet M, Stivanello M, Sacchetto G, Angeli A (1999) Differential patterns of bone turnover in relation to bone pain and disease extent in bone in cancer patients with skeletal metastases. Clin Chem 45:1240-1247
10. Meyers PA, Heller G, Healey J, Huvos A, Lane J, Marcove R, Applewhite A, Vlamis V, Rosen G (1992) Chemotherapy for nonmetastatic osteogenic sarcoma: the Memorial Sloan-Kettering experience. J Clin Oncol 10:5-15
11. Ferrari S, Bertoni F, Mercuri M, Picci P, Giacomini S, Longhi A, Bacci G (2001) Predictive factors of disease-free survival for non-metastatic osteosarcoma of the extremity: an analysis of 300 patients treated at the Rizzoli Institute. Ann Oncol 12:1145-1150
12. Arikoski P, Komulainen J, Riikonen P, Voutilainen R, Knip M, Kroger H (1999) Alterations in bone turnover and impaired development of bone mineral density in newly diagnosed children with cancer: a 1-year prospective study. J Clin Endocrinol Metab 84:3174-3181
13. Koizumi M, Maeda H, Yoshimura K, Yamauchi T, Kawai T, Ogata E (1997) Dissociation of bone formation markers in bone metastasis of prostate cancer. Br J Cancer 75:1601-1604
14. Hopyan S, Gokgoz N, Bell RS, Andrulis IL, Alman BA, Wunder JS (1999) Expression of osteocalcin and its transcriptional regulators core-binding factor alpha 1 and MSX2 in osteoid-forming tumours. J Orthop Res 17:633-638