Molecular pathology of atypical polypoid adenomyoma of the uterus

Human Pathology

Volumn 34, Issue 8, 2003, Pages 784-788

  Ota, Shunichiro ^b   Catasus, Lluis ^b   Matias Guiu, Xavier ^b   Bussaglia, Elena ^b   Lagarda, Helena ^b   Pons, Cristina ^b   Muñoz, Josefina ^b   Kamura, Toshiharu ^b   Prat, Jaime ^a  

^a HOSPITAL DE LA SANTA CREU I SANT PAU   (Spain)

^b NONE

Author keywords

Atypical polypoid adenomyoma; Endometrial tumor; Microsatellite instability; Promoter hypermethylation of MLH 1; Tumorigenesis; catenin

Indexed keywords

BETA CATENIN; DNA; PHOSPHATIDYLINOSITOL 3,4,5 TRISPHOSPHATE 3 PHOSPHATASE; PROTEIN MLH1; PROTEIN MSH2;

ADENOMYOMA; ADULT; AGED; ARTICLE; ATYPICAL POLYPOID ADENOMYOMA; CARCINOGENESIS; CLINICAL ARTICLE; CTNNB1 GENE; DNA METHYLATION; ENDOMETRIOID CARCINOMA; FEMALE; GENE; GENE MUTATION; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; MICROSATELLITE INSTABILITY; POLYMERASE CHAIN REACTION; PROMOTER REGION; UTERUS TUMOR;

EID: 0041386123     PISSN: 00468177     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0046-8177(03)00246-6     Document Type: Article

References (30)

1. Mazur MT: Atypical polypoid adenomyoma of the endometrium. Am J Surg Pathol 5:473-482, 1981
2. Longacre TA, Chung MH, Rouse RV, et al: Atypical polypoid adenomyofibroma (atypical polypoid adenomyomas) of the uterus. Am J Surg Pathol 20:1-20, 1996
3. Sugiyama T, Ota S, Nishida T, et al: Two cases of endometrial adenocarcinoma arising from atypical polypoid adenomyoma. Gynecol Oncol 71:141-144, 1998
4. Catasus L, Machin P, Matias-Guiu X, et al: Microsatellite instability in endometrial carcinomas: Clinicopathologic correlations in a series of 42 cases. HUM PATHOL 29:1160-1164, 1998
5. Palacios J, Catasus L, Moreno-Bueno G, et al: β-and γ-catenin expression in endometrial carcinoma. Relationship with clinicopathological futures and microsatellite instability. Virchows Arch 438:464-469, 2001
6. Lagarda H, Catasus L, Arguelles R, et al: K-ras mutations in endometrial carcinoma with microsatellite instability. J Pathol 193: 193-199, 2001
7. Matias-Guiu X, Catasus L, Bussaglia E, et al: Molecular pathology of endometrial hyperplasia and carcinoma. HUM PATHOL 32:569-577, 2001
8. Machin P, Catasus L, Pons C, et al: CTNNB-1 mutation and β-catenin expression in endometrial carcinomas. HUM PATHOL 33: 206-212, 2002
9. Catasus L, Matias-Guiu X, Machin P, et al: Frame-shift mutation at coding mononucleotide repeat microsatellite in endometrial carcinoma with microsatellite instability. Cancer 88:2290-2296, 2000
10. Esteller M, Catasus L, Matias-Guiu X, et al: HMLH-promoter hypermethylation is an early event in human endometrial tumorigenesis. Am J Pathol 155:1767-1772, 1999
11. Gras E, Catasus L, Arguelles RM, et al: Microsatellite instability, MLH-1 promoter hypermethylation and frame-shift mutations at coding mononucleotide repeat microsatellites in ovarian tumors. Cancer 92:2829-2836, 2001
12. Esteller M, Levine R, Baylin SB, et al: MLH-1 promoter hypermethylation is associated with the microsatellite instability phenotype in sporadic endometrial carcinomas. Oncogene 16:2413-2417, 1998
13. Delprado WJ, Stevens SMB, Baird PJ: Atypical polypoid adenomyoma: A case record with ultrastructural examination. Pathology 17:522-525, 1985
14. Di Palma S, Santini D, Martinelli G: Atypical polypoid adenomyoma of the uterus. An immunohistochemical study of a case. Tumori 75:292-295, 1989
15. Young RH, Treger T, Scully RE: Atypical polypoid adenomyoma of the uterus. A report of 27 cases. Am J Clin Pathol 86:139-145, 1986
16. Kay S, Frable WJ, Goplerud DR: Endometrial carcinoma arising in a large polypoid adenomyoma of the uterus. Int J Gynecol Pathol 7:391-398, 1988
17. Staros EB, Shilkitus WF: Atypical polypoid adenomyoma with carcinomatous transformation: A case report. Surg Pathol 4:157-166, 1991
18. Bussaglia E, del Rio E, Matias-Guiu X, et al: PTEN mutations in endometrial carcinomas. A molecular and clinicopathologic analysis of 38 cases. HUM PATHOL 31:312-317, 2000
19. Miller JR, Moon RT: Signal transduction through β-catenin and specification of cell fate during embryogenesis. Genes Dev 182: 2527-2539, 1996
20. Ilyas M, Tomlinson IPM: The interactions of APC, E-cadherin and β-catenin in tumor development and progression. J Pathol 182:128-137, 1997
21. Miller JR, Hocking AM, Brown JD, et al: Mechanism and function of signal transduction by the Wnt/Ca pathway. Oncogene 18:7860-7872, 1999
22. Minemitsu S, Albert I, Souza B, et al: Regulation of intracellular β-catenin levels by the adenomatous polyposis coli (APC) tumor-suppressor protein. Proc Natl Acad Sci U S A 92:3046-3050, 1995
23. Peifer M: β-catenin as oncogene. Science 275:1752-1753, 1997
24. Fukuchi T, Sakamoto M, Tsuda N: β-catenin mutation in carcinoma of the uterine endometrium. Cancer Res 58:3526-3528, 1998
25. Kobayashi K, Sagae S, Nishioka Y, et al: Mutation of the β-catenin gene in endometrial carcinoma. Jpn J Cancer Res 90:55-59, 1999
26. Mirabelli-Primdahl L, Gryfe R, Kim H, et al: β-catenin mutations are specific for colorectal carcinomas with microsatellite instability but occur in endometrioid carcinoma irrespective of mutator pathway. Cancer Res 59:3346-3351, 1999
27. Schlosshauer PW, Priog EC, Levine RL, et al: Mutation analysis of the CTNNB-1 and APC gene in uterine endometrial carcinoma. Mod Pathol 13:1066-1071, 2000
28. Saegusa M, Okayasu I: Frequent nuclear/β-catenin accumulation and associated mutations in endometrioid type endometrial and ovarian carcinomas with squamous differentiation. J Pathol 194: 59-67, 2001
29. Tanaka S, Akiyoshi T, Mori M, et al: A novel frizzled gene identified in human esophageal carcinoma mediates APC/β-catenin signals. Proc Natl Acad Sci U S A 95:10164-10169, 1998
30. Abu-Jawdeh G, Comella N, Tomita Y, et al: Differential expression of frpHE, a novel human stromal protein of secreted frizzed gene family, during the endometrial cycle and malignancy. Lab Invest 79:439-447, 1999