The new anti-oncogene Clusterin and the molecular profiling of Prostate Cancer progression and prognosis;Il nuovo anti-oncogene Clusterina e il profilo molecolare della progressione e della prognosi del cancro prostatico

Acta Biomedica de l'Ateneo Parmense

Volumn 74, Issue 2, 2003, Pages 101-104

  Bettuzzi, Saverio ^a  

^a UNIVERSITY OF PARMA   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

CLUSTERIN; GLYCOPROTEIN;

ANIMAL CELL; CANCER GROWTH; CELL CYCLE; CELL IMMORTALIZATION; CONFERENCE PAPER; GENE OVEREXPRESSION; HUMAN; HUMAN CELL; MALE; NONHUMAN; ONCOGENE; PROGNOSIS; PROSTATE CANCER; PROSTATE DISEASE; RAT; SIMIAN VIRUS 40;

APOPTOSIS; BLOTTING, NORTHERN; BLOTTING, WESTERN; CELL LINE; CLUSTERIN; COHORT STUDIES; DOWN-REGULATION; FOLLOW-UP STUDIES; GENE EXPRESSION; GENES, TUMOR SUPPRESSOR; GLYCOPROTEINS; HUMANS; IMMUNOHISTOCHEMISTRY; MALE; MOLECULAR CHAPERONES; NEOPLASM RECURRENCE, LOCAL; PROGNOSIS; PROSTATE-SPECIFIC ANTIGEN; PROSTATIC NEOPLASMS; RESEARCH; TUMOR MARKERS, BIOLOGICAL;

EID: 0041322503     PISSN: 03924203     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Conference Paper

References (6)

1. Bettuzzi S, Hiipakka RA, Gilna P, Lia ST. Identification of an androgen-repressed mRNA in rat ventral prostate as coding for sulphated glycoprotein 2 by cDNA cloning and sequence analysis. Biochem J 1989; 257: 293-6.
2. Rosenberg ME, Silkensen J. Clusterin: physiologic and pathophysiologic considerations. Int J Biochem Cell Biol 1995; 27: 633-45.
3. Bettuzzi S, Astancolle S, Guidetti G, Moretti M, Tiozzo R, Corti A. Clusterin (SGP-2) gene expression is cell-cycle dependent in normal human dermal fibroblasts. FEBS Lett 1999; 448: 297-300.
4. Bettuzzi S, Scorcioni F, Astancolle S, Davalli P, Scaltriti M, Corti A. Clusterin (SGP-2) transient overexpression decreases proliferation rate of SV40-immortalized human prostate epithelial cells by slowing down cell cycle progression. Oncogene 2002; 21: 4328-34.
5. Bettuzzi S, Davalli P, Astancolle S, et al. Tumor progression is accompanied by significant changes in the levels of expression of polyamine metabolism regulatory genes and clusterin (sulfated glycoprotein 2) in human prostate cancer speciments. Cancer Res 2000; 60: 28-34.
6. Koch Brandt C, Morgans C. Clusterin: a role in cell survival in the face of apoptosis? Prog Mol Subcell Biol 1996; 16: 130-49.