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Volumn 22, Issue 14, 2003, Pages 3696-3704

Imprinted silencing of Slc22a2 and Slc22a3 does not need transcriptional overlap between Igf2r and Air

Author keywords

Genomic imprinting; Igf2r; Non coding RNA; Slc22a2; Slc22a3

Indexed keywords

DOUBLE STRANDED RNA; GENE PRODUCT; ORGANIC CATION TRANSPORTER 2; ORGANIC CATION TRANSPORTER 3; PROTEIN AIR; PROTEIN IGF2R; THYMIDINE KINASE; UNCLASSIFIED DRUG;

EID: 0041312649     PISSN: 02614189     EISSN: None     Source Type: Journal    
DOI: 10.1093/emboj/cdg341     Document Type: Article
Times cited : (78)

References (45)
  • 1
    • 0035228079 scopus 로고    scopus 로고
    • X-chromosome inactivation: Counting, choice and initiation
    • Avner, P. and Heard, E. (2001) X-chromosome inactivation: counting, choice and initiation. Nat. Rev. Genet., 2, 59-67.
    • (2001) Nat. Rev. Genet. , vol.2 , pp. 59-67
    • Avner, P.1    Heard, E.2
  • 3
    • 0035910395 scopus 로고    scopus 로고
    • Insulators and boundaries: Versatile regulatory elements in the eukaryotic genome
    • Bell, A.C., West, A.G. and Felsenfeld, G. (2001) Insulators and boundaries: versatile regulatory elements in the eukaryotic genome. Science, 291, 447-450.
    • (2001) Science , vol.291 , pp. 447-450
    • Bell, A.C.1    West, A.G.2    Felsenfeld, G.3
  • 4
    • 0036186168 scopus 로고    scopus 로고
    • The KLHL1-antisense transcript (KLHL1AS) is evolutionarily conserved
    • Benzow, K.A. and Koob, M.D. (2002) The KLHL1-antisense transcript (KLHL1AS) is evolutionarily conserved. Mamm. Genome, 13, 134-141.
    • (2002) Mamm. Genome , vol.13 , pp. 134-141
    • Benzow, K.A.1    Koob, M.D.2
  • 5
    • 0034326859 scopus 로고    scopus 로고
    • Sequence and functional comparison in the Beckwith-Wiedemann region: Implications for a novel imprinting centre and extended imprinting
    • Engemann, S., Strodicke, M., Paulsen, M., Franck, O., Reinhardt, R., Lane, N., Reik, W. and Walter, J. (2000) Sequence and functional comparison in the Beckwith-Wiedemann region: implications for a novel imprinting centre and extended imprinting. Hum. Mol. Genet., 9, 2691-2706.
    • (2000) Hum. Mol. Genet. , vol.9 , pp. 2691-2706
    • Engemann, S.1    Strodicke, M.2    Paulsen, M.3    Franck, O.4    Reinhardt, R.5    Lane, N.6    Reik, W.7    Walter, J.8
  • 6
    • 0036831864 scopus 로고    scopus 로고
    • Regional loss of imprinting and growth deficiency in mice with a targeted deletion of KvDMR1
    • Fitzpatrick, G.V., Soloway, P.D. and Higgins, M.J. (2002) Regional loss of imprinting and growth deficiency in mice with a targeted deletion of KvDMR1. Nat. Genet., 32, 426-431.
    • (2002) Nat. Genet. , vol.32 , pp. 426-431
    • Fitzpatrick, G.V.1    Soloway, P.D.2    Higgins, M.J.3
  • 7
    • 0342887321 scopus 로고    scopus 로고
    • Mammals that break the rules: Genetics of marsupials and monotremes
    • Graves, J.A. (1996) Mammals that break the rules: genetics of marsupials and monotremes. Annu. Rev. Genet., 30, 233-260.
    • (1996) Annu. Rev. Genet. , vol.30 , pp. 233-260
    • Graves, J.A.1
  • 8
    • 0033853988 scopus 로고    scopus 로고
    • Intergenic transcription and developmental remodeling of chromatin subdomains in the human β-globin locus
    • Gribnau, J., Diderich, K., Pruzina, S., Calzolari, R. and Fraser, P. (2000) Intergenic transcription and developmental remodeling of chromatin subdomains in the human β-globin locus. Mol. Cell, 5, 377-386.
    • (2000) Mol. Cell , vol.5 , pp. 377-386
    • Gribnau, J.1    Diderich, K.2    Pruzina, S.3    Calzolari, R.4    Fraser, P.5
  • 9
    • 0037062951 scopus 로고    scopus 로고
    • RNA interference
    • Hannon, G.J. (2002) RNA interference. Nature, 418, 244-251.
    • (2002) Nature , vol.418 , pp. 244-251
    • Hannon, G.J.1
  • 10
    • 0034713275 scopus 로고    scopus 로고
    • CTCF mediates methylation-sensitive enhancer-blocking activity at the H19/Igf2 locus
    • Hark, A.T., Schoenherr, C.J., Katz, D.J., Ingram, R.S., Levorse, J.M. and Tilghman, S.M. (2000) CTCF mediates methylation-sensitive enhancer-blocking activity at the H19/Igf2 locus. Nature, 405, 486-489.
    • (2000) Nature , vol.405 , pp. 486-489
    • Hark, A.T.1    Schoenherr, C.J.2    Katz, D.J.3    Ingram, R.S.4    Levorse, J.M.5    Tilghman, S.M.6
  • 12
    • 0034284693 scopus 로고    scopus 로고
    • Targeted disruption of the human LIT1 locus defines a putative imprinting control element playing an essential role in Beckwith-Wiedemann syndrome
    • Horike, S., Mitsuya, K., Meguro, M., Kotobuki, N., Kashiwagi, A., Notsu, T., Schulz, T.C., Shirayoshi, Y. and Oshimura, M. (2000) Targeted disruption of the human LIT1 locus defines a putative imprinting control element playing an essential role in Beckwith-Wiedemann syndrome. Hum. Mol. Genet., 9, 2075-2083.
    • (2000) Hum. Mol. Genet. , vol.9 , pp. 2075-2083
    • Horike, S.1    Mitsuya, K.2    Meguro, M.3    Kotobuki, N.4    Kashiwagi, A.5    Notsu, T.6    Schulz, T.C.7    Shirayoshi, Y.8    Oshimura, M.9
  • 13
    • 0025288707 scopus 로고
    • N-myc mRNA forms an RNA-RNA duplex with endogenous antisense transcripts
    • Krystal, G.W., Armstrong, B.C. and Battey, J.F. (1990) N-myc mRNA forms an RNA-RNA duplex with endogenous antisense transcripts. Mol. Cell. Biol., 10, 4180-4191.
    • (1990) Mol. Cell. Biol. , vol.10 , pp. 4180-4191
    • Krystal, G.W.1    Armstrong, B.C.2    Battey, J.F.3
  • 14
    • 0028575985 scopus 로고
    • Loss of the imprinted IGF2/cation-independent mannose 6-phosphate receptor results in fetal overgrowth and perinatal lethality
    • Lau, M.M., Stewart, C.E., Liu, Z., Bhatt, H., Rotwein, P. and Stewart, C.L. (1994) Loss of the imprinted IGF2/cation-independent mannose 6-phosphate receptor results in fetal overgrowth and perinatal lethality. Genes Dev., 8, 2953-2963.
    • (1994) Genes Dev. , vol.8 , pp. 2953-2963
    • Lau, M.M.1    Stewart, C.E.2    Liu, Z.3    Bhatt, H.4    Rotwein, P.5    Stewart, C.L.6
  • 15
    • 0037453015 scopus 로고    scopus 로고
    • Molecular links between X-inactivation and autosomal imprinting: X-inactivation as a driving force for the evolution of imprinting?
    • Lee, J.T. (2003) Molecular links between X-inactivation and autosomal imprinting: X-inactivation as a driving force for the evolution of imprinting? Curr. Biol., 13, R242-R254.
    • (2003) Curr. Biol. , vol.13
    • Lee, J.T.1
  • 16
    • 0034724647 scopus 로고    scopus 로고
    • Mit1/Lb9 and Copg2, new members of mouse imprinted genes closely linked to Peg 1/Mest(1)
    • Lee, Y.J., Park, C.W., Hahn, Y., Park, J., Lee, J., Yun, J.H., Hyun, B. and Chung, J.H. (2000) Mit1/Lb9 and Copg2, new members of mouse imprinted genes closely linked to Peg 1/Mest(1). FEBS Lett., 472, 230-234.
    • (2000) FEBS Lett. , vol.472 , pp. 230-234
    • Lee, Y.J.1    Park, C.W.2    Hahn, Y.3    Park, J.4    Lee, J.5    Yun, J.H.6    Hyun, B.7    Chung, J.H.8
  • 17
    • 0036733675 scopus 로고    scopus 로고
    • Chromatin modification and epigenetic reprogramming in mammalian development
    • Li, E. (2002) Chromatin modification and epigenetic reprogramming in mammalian development. Nat. Rev. Genet., 3, 662-673.
    • (2002) Nat. Rev. Genet. , vol.3 , pp. 662-673
    • Li, E.1
  • 18
    • 0027378582 scopus 로고
    • Role for DNA methylation in genomic imprinting
    • Li, E., Beard, C. and Jaenisch, R. (1993) Role for DNA methylation in genomic imprinting. Nature, 366, 362-365.
    • (1993) Nature , vol.366 , pp. 362-365
    • Li, E.1    Beard, C.2    Jaenisch, R.3
  • 19
    • 0029919678 scopus 로고    scopus 로고
    • Expression of the rat BFGF antisense RNA transcript is tissue-specific and developmentally regulated
    • Li, A.W., Seyoum, G., Shiu, R.P. and Murphy, P.R. (1996) Expression of the rat BFGF antisense RNA transcript is tissue-specific and developmentally regulated. Mol. Cell. Endocrinol., 118, 113-123.
    • (1996) Mol. Cell. Endocrinol. , vol.118 , pp. 113-123
    • Li, A.W.1    Seyoum, G.2    Shiu, R.P.3    Murphy, P.R.4
  • 20
    • 0030221121 scopus 로고    scopus 로고
    • Mouse mutants lacking the type 2 IGF receptor (IGF2R) are rescued from perinatal lethality in Igf2 and Igf1r null backgrounds
    • Ludwig, T., Eggenschwiler, J., Fisher, P., D'Ercole, A.J., Davenport, M.L. and Efstratiadis, A. (1996) Mouse mutants lacking the type 2 IGF receptor (IGF2R) are rescued from perinatal lethality in Igf2 and Igf1r null backgrounds. Dev. Biol., 177, 517-535.
    • (1996) Dev. Biol. , vol.177 , pp. 517-535
    • Ludwig, T.1    Eggenschwiler, J.2    Fisher, P.3    D'Ercole, A.J.4    Davenport, M.L.5    Efstratiadis, A.6
  • 21
    • 0034118382 scopus 로고    scopus 로고
    • The imprinted antisense RNA at the Igf2r locus overlaps but does not imprint Mas1
    • Lyle, R. et al. (2000) The imprinted antisense RNA at the Igf2r locus overlaps but does not imprint Mas1. Nat. Genet., 25, 19-21.
    • (2000) Nat. Genet. , vol.25 , pp. 19-21
    • Lyle, R.1
  • 22
    • 0032603450 scopus 로고    scopus 로고
    • Imprinting and X-chrofnosome inactivation
    • Lyon, M.F. (1999) Imprinting and X-chrofnosome inactivation. Results Probl. Cell Differ., 25, 73-90.
    • (1999) Results Probl. Cell Differ. , vol.25 , pp. 73-90
    • Lyon, M.F.1
  • 23
    • 0033665147 scopus 로고    scopus 로고
    • Sequence and comparative analysis of the mouse 1-megabase region orthologous to the human 11p15 imprinted domain
    • Onyango, P., Miller, W., Lehoczky, J., Leung, C.T., Birren, B., Wheelan, S., Dewar, K. and Feinberg, A.P. (2000) Sequence and comparative analysis of the mouse 1-megabase region orthologous to the human 11p15 imprinted domain. Genome Res., 10, 1697-1710.
    • (2000) Genome Res. , vol.10 , pp. 1697-1710
    • Onyango, P.1    Miller, W.2    Lehoczky, J.3    Leung, C.T.4    Birren, B.5    Wheelan, S.6    Dewar, K.7    Feinberg, A.P.8
  • 24
    • 0031655391 scopus 로고    scopus 로고
    • Evolutionary conservation and tissue-specific processing of Hoxa 11 antisense transcripts
    • Potter, S.S. and Branford, W.W. (1998) Evolutionary conservation and tissue-specific processing of Hoxa 11 antisense transcripts. Mamm. Genome, 9, 799-806.
    • (1998) Mamm. Genome , vol.9 , pp. 799-806
    • Potter, S.S.1    Branford, W.W.2
  • 25
    • 0035234557 scopus 로고    scopus 로고
    • Genomic imprinting: Parental influence on the genome
    • Reik, W. and Walter, J. (2001) Genomic imprinting: parental influence on the genome. Nat. Rev. Genet., 2, 21-32.
    • (2001) Nat. Rev. Genet. , vol.2 , pp. 21-32
    • Reik, W.1    Walter, J.2
  • 26
    • 0036718498 scopus 로고    scopus 로고
    • Antisense RNA in imprinting: Spreading silence through air
    • Rougeulle, C. and Heard, E. (2002) Antisense RNA in imprinting: spreading silence through Air. Trends Genet., 18, 434-437.
    • (2002) Trends Genet. , vol.18 , pp. 434-437
    • Rougeulle, C.1    Heard, E.2
  • 27
    • 0032067559 scopus 로고    scopus 로고
    • An imprinted antisense RNA overlaps UBE3A and a second maternally expressed transcript
    • Rougeulle, C., Cardoso, C., Fontes, M., Colleaux, L. and Lalande, M. (1998) An imprinted antisense RNA overlaps UBE3A and a second maternally expressed transcript. Nat. Genet., 19, 15-16.
    • (1998) Nat. Genet. , vol.19 , pp. 15-16
    • Rougeulle, C.1    Cardoso, C.2    Fontes, M.3    Colleaux, L.4    Lalande, M.5
  • 28
    • 0033578336 scopus 로고    scopus 로고
    • Enhancer competition between H19 and Igf2 does not mediate their imprinting
    • Schmidt, J.V., Levorse, J.M. and Tilghman, S.M. (1999) Enhancer competition between H19 and Igf2 does not mediate their imprinting. Proc. Natl Acad. Sci. USA, 96, 9733-9738.
    • (1999) Proc. Natl. Acad. Sci. USA , vol.96 , pp. 9733-9738
    • Schmidt, J.V.1    Levorse, J.M.2    Tilghman, S.M.3
  • 29
    • 0029566108 scopus 로고
    • A cre-transgenic mouse strain for the ubiquitous deletion of loxP-flanked gene segments including deletion in germ cells
    • Schwenk, F., Baron, U. and Rajewsky, K. (1995) A cre-transgenic mouse strain for the ubiquitous deletion of loxP-flanked gene segments including deletion in germ cells. Nucleic Acids Res., 23, 5080-5081.
    • (1995) Nucleic Acids Res. , vol.23 , pp. 5080-5081
    • Schwenk, F.1    Baron, U.2    Rajewsky, K.3
  • 30
    • 0036371842 scopus 로고    scopus 로고
    • The origins of genomic imprinting in mammals
    • Sleutels, F. and Barlow, D.P. (2002) The origins of genomic imprinting in mammals. Adv. Genet., 46, 119-163.
    • (2002) Adv. Genet. , vol.46 , pp. 119-163
    • Sleutels, F.1    Barlow, D.P.2
  • 31
    • 0037075032 scopus 로고    scopus 로고
    • The non-coding Air RNA is required for silencing autosomal imprinted genes
    • Sleutels, F., Zwart, R. and Barlow, D.P. (2002) The non-coding Air RNA is required for silencing autosomal imprinted genes. Nature, 415, 810-813.
    • (2002) Nature , vol.415 , pp. 810-813
    • Sleutels, F.1    Zwart, R.2    Barlow, D.P.3
  • 32
    • 0033529207 scopus 로고    scopus 로고
    • A maternally methylated CpG island in KvLQT1 is associated with an antisense paternal transcript and loss of imprinting in Beckwith-Wiedemann syndrome
    • Smilinich, N.J. et al. (1999) A maternally methylated CpG island in KvLQT1 is associated with an antisense paternal transcript and loss of imprinting in Beckwith-Wiedemann syndrome. Proc. Natl Acad. Sci. USA, 96, 8064-8069.
    • (1999) Proc. Natl. Acad. Sci. USA , vol.96 , pp. 8064-8069
    • Smilinich, N.J.1
  • 33
    • 0027400888 scopus 로고
    • Maternal-specific methylation of the imprinted mouse Igf2r locus identifies the expressed locus as carrying the imprinting signal
    • Stoeger, R., Kubicka, P., Liu, C.G., Kafri, T., Razin, A., Cedar, H. and Barlow, D.P. (1993) Maternal-specific methylation of the imprinted mouse Igf2r locus identifies the expressed locus as carrying the imprinting signal. Cell, 73, 61-71.
    • (1993) Cell , vol.73 , pp. 61-71
    • Stoeger, R.1    Kubicka, P.2    Liu, C.G.3    Kafri, T.4    Razin, A.5    Cedar, H.6    Barlow, D.P.7
  • 34
    • 0034193691 scopus 로고    scopus 로고
    • Maternal-specific footprints at putative CTCF sites in the H19 imprinting control region give evidence for insulator function
    • Szabo, P., Tang, S.H., Rentsendorj, A., Pfeifer, G.P. and Mann, J.R. (2000) Maternal-specific footprints at putative CTCF sites in the H19 imprinting control region give evidence for insulator function. Curr. Biol., 10, 607-610.
    • (2000) Curr. Biol. , vol.10 , pp. 607-610
    • Szabo, P.1    Tang, S.H.2    Rentsendorj, A.3    Pfeifer, G.P.4    Mann, J.R.5
  • 35
    • 0028949203 scopus 로고
    • Regulation of human RPS14 transcription by intronic antisense RNAs and ribosomal protein S14
    • Tasheva, E.S. and Roufa, D.J. (1995) Regulation of human RPS14 transcription by intronic antisense RNAs and ribosomal protein S14. Genes Dev., 9, 304-316.
    • (1995) Genes Dev. , vol.9 , pp. 304-316
    • Tasheva, E.S.1    Roufa, D.J.2
  • 36
    • 0034705264 scopus 로고    scopus 로고
    • Molecular biology. Mothers setting boundaries
    • Thorvaldsen, J.L. and Bartolomei, M.S. (2000) Molecular biology. Mothers setting boundaries. Science, 288, 2145-2146.
    • (2000) Science , vol.288 , pp. 2145-2146
    • Thorvaldsen, J.L.1    Bartolomei, M.S.2
  • 37
    • 0032419812 scopus 로고    scopus 로고
    • Deletion of the H19 differentially methylated domain results in loss of imprinted expression of H19 and Igf2
    • Thorvaldsen, J.L., Duran, K.L. and Bartolomei, M.S. (1998) Deletion of the H19 differentially methylated domain results in loss of imprinted expression of H19 and Igf2. Genes Dev., 12, 3693-3702.
    • (1998) Genes Dev. , vol.12 , pp. 3693-3702
    • Thorvaldsen, J.L.1    Duran, K.L.2    Bartolomei, M.S.3
  • 38
    • 0035812647 scopus 로고    scopus 로고
    • Promoter suppression in cultured mammalian cells can be blocked by the chicken β-globin chromatin insulator 5′HS4 and matrix/scaffold attachment regions
    • Villemure, J.F., Savard, N. and Belmaaza, A. (2001) Promoter suppression in cultured mammalian cells can be blocked by the chicken β-globin chromatin insulator 5′HS4 and matrix/scaffold attachment regions. J. Mol. Biol., 312, 963-974.
    • (2001) J. Mol. Biol. , vol.312 , pp. 963-974
    • Villemure, J.F.1    Savard, N.2    Belmaaza, A.3
  • 39
    • 0037072661 scopus 로고    scopus 로고
    • Regulation of heterochromatic silencing and histone H3 lysine-9 methylation by RNAi
    • Volpe, T.A., Kidner, C., Hall, I.M., Teng, G., Grewal, S.I. and Martienssen,R.A. (2002) Regulation of heterochromatic silencing and histone H3 lysine-9 methylation by RNAi. Science, 297, 1833-1837.
    • (2002) Science , vol.297 , pp. 1833-1837
    • Volpe, T.A.1    Kidner, C.2    Hall, I.M.3    Teng, G.4    Grewal, S.I.5    Martienssen, R.A.6
  • 40
    • 0031662164 scopus 로고    scopus 로고
    • Transcription of IAP endogenous retroviruses is constrained by cytosine methylation
    • Walsh, C.P., Chaillet, J.R. and Bestor, T.H. (1998) Transcription of IAP endogenous retroviruses is constrained by cytosine methylation. Nat. Genet., 20, 116-117.
    • (1998) Nat. Genet. , vol.20 , pp. 116-117
    • Walsh, C.P.1    Chaillet, J.R.2    Bestor, T.H.3
  • 41
    • 0027999284 scopus 로고
    • Regulation of embryonic growth and lysosomal targeting by the imprinted Igf2/Mpr gene
    • Wang, Z.Q., Fung, M.R., Barlow, D.P. and Wagner, E.F. (1994) Regulation of embryonic growth and lysosomal targeting by the imprinted Igf2/ Mpr gene. Nature, 372, 464-467.
    • (1994) Nature , vol.372 , pp. 464-467
    • Wang, Z.Q.1    Fung, M.R.2    Barlow, D.P.3    Wagner, E.F.4
  • 43
    • 0033637110 scopus 로고    scopus 로고
    • A shift from reversible to irreversible X inactivation is triggered during ES cell differentiation
    • Wutz, A. and Jaenisch, R. (2000) A shift from reversible to irreversible X inactivation is triggered during ES cell differentiation. Mol. Cell, 5, 695-705.
    • (2000) Mol. Cell , vol.5 , pp. 695-705
    • Wutz, A.1    Jaenisch, R.2
  • 44
    • 0034743736 scopus 로고    scopus 로고
    • Non-imprinted Igf2r expression decreases growth and rescues the Tme mutation in mice
    • Wutz, A., Theussl, H.C., Dausman, J., Jaenisch, R., Barlow, D.P. and Wagner, E.F. (2001) Non-imprinted Igf2r expression decreases growth and rescues the Tme mutation in mice. Development, 128, 1881-1887.
    • (2001) Development , vol.128 , pp. 1881-1887
    • Wutz, A.1    Theussl, H.C.2    Dausman, J.3    Jaenisch, R.4    Barlow, D.P.5    Wagner, E.F.6
  • 45
    • 0035883743 scopus 로고    scopus 로고
    • Bidirectional action of the Igf2r imprint control element on upstream and downstream imprinted genes
    • Zwart, R., Sleutels, F., Wutz, A., Schinkel, A.H. and Barlow, D.P. (2001) Bidirectional action of the Igf2r imprint control element on upstream and downstream imprinted genes. Genes Dev., 15, 2361-2366.
    • (2001) Genes Dev. , vol.15 , pp. 2361-2366
    • Zwart, R.1    Sleutels, F.2    Wutz, A.3    Schinkel, A.H.4    Barlow, D.P.5


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