New tetracyclic colchicinoids from the reaction of N-deacetylthiocolchicine and N-deacetylcolchicine with nitrous acid and tert-butyl nitrite

Helvetica Chimica Acta

Volumn 86, Issue 6, 2003, Pages 2082-2089

  Danieli, Bruno ^a   Lesma, Giordano ^a   Passarella, Daniele ^a   Prosperi, Davide ^a   Sacchetti, Alessandro ^a   Silvani, Alessandra ^a   Destro, Riccardo ^a   May, Emanuela ^a   Bombardelli, Ezio ^b  

^a UNIVERSITY OF MILAN   (Italy)

^b INDENA S P A   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

CRYSTAL STRUCTURE; INORGANIC ACIDS; SPECTROSCOPIC ANALYSIS; X RAYS;

DEMYANOV-REARRANGEMENT PRODUCTS;

NITROGEN COMPOUNDS;

5,6 DIHYDRO 6 (HYDROXYMETHYL) 1,2,3 TRIMETHOXY 9 (METHYLSULFANYL) 8H CYCLOHEPTA[A]NAPHTHALEN 8 ONE; 5,6 DIHYDRO 6 (HYDROXYMETHYL) 1,2,3,9 TETRAMETHOXY 8H CYCLOHEPTA[A]NAPHTHALEN 8 ONE; 6,6A DIHYDRO 1,2 DIMETHOXY 9 (METHYLSULFANYL) 3H CYCLOHEPTA[3,4]CYCLOBUTA[1,2 C]INDENE 3,8(5H) DIONE; 6,6A DIHYDRO 1,2,9 TRIMETHOXY 3H CYCLOHEPTA[3,4]CYCLOBUTA[1,2 C]INDENE 3,8(5H) DIONE; 7,8 DIHYDRO 10,11,12 TRIMETHOXY 3 (METHYLSULFANYL)BENZO[4,5]HEPTALENO[1,10 CD]PYRAZOL 4(5H) ONE; COLCHICINE DERIVATIVE; DEACETYLCOLCHICINE; DEACETYLTHIOCOLCHICINE; NITRITE; NITROUS ACID; PYRAZOLE DERIVATIVE; TERT BUTYL NITRITE; UNCLASSIFIED DRUG;

ARTICLE; CARBON NUCLEAR MAGNETIC RESONANCE; CHEMICAL BOND; CHEMICAL MODIFICATION; CHEMICAL REACTION; CONFORMATIONAL TRANSITION; CRYSTAL STRUCTURE; DRUG CONFORMATION; DRUG STRUCTURE; DRUG SYNTHESIS; MASS SPECTROMETRY; PRIORITY JOURNAL; PROTON NUCLEAR MAGNETIC RESONANCE; REACTION ANALYSIS; STEREOCHEMISTRY; STRUCTURE ANALYSIS; SUBSTITUTION REACTION; X RAY CRYSTALLOGRAPHY;

EID: 0041303391     PISSN: 0018019X     EISSN: None     Source Type: Journal    
DOI: 10.1002/hlca.200390164     Document Type: Article

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