Innovative approaches to the imidazo[4,5-b]pyridine ring system. Development of an efficient process for industrial-scale production of a key intermediate for potent angiotensin II receptor antagonists

Chimia

Volumn 51, Issue 6, 1997, Pages 280-282

  Stucky, Gerhard C ^a   Roduit, Jean Paul ^b   Schmidt, Beat ^b  

^a LONZA AG   (Switzerland)

^b NONE

Author keywords

[No Author keywords available]

Indexed keywords

EID: 0041193232     PISSN: 00094293     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (9)

1. P.K. Chakravarty, E.M Naylor, A. Chen, R.S.L. Chang, T. Chen, K.A. Faust, V.J. Lotti, S.D. Kivilighn, R.A. Gable, G.J. Zingaro, T.W. Shorn, L.W. Schaffer, T.P. Broten, P.K. Siegl, A.A. Patchett, W.J. Greenlee, J. Med. Chem. 1994, 37, 4068.
2. S. Bagley, W.J. Greenlee, D.S. Dhanoa, A.A. Patchett, US Pat. 5.151.435, 1991.
3. C.H. Senanyake, L.E. Fredenburgh, R.A. Reamer, J. Liu, R.D. Larsen, T.R. Verhoeven, P.J. Reider, Tetrahedron Lett. 1994, 35, 5775.
4. C.H. Senanyake, L.E. Fredenburgh, R.A. Reamer, R.D. Larsen, T.R. Verhoeven, P.J. Reider, J. Am. Chem. Soc. 1994, 116, 7947.
5. H. Mertens, R. Troschütz, H.J. Roth, Liebigs Ann. Chem. 1986, 380.
6. DE 2734070, B.J. Price, J.W. Clitherow, J. Bradshaw, CA, 88, 190580.
7. R. Troschütz, A. Lückel, Arch. Pharm. 1992, 325, 785.
8. EP 456510 (Merck), S.S.T. Chen. G. Doss, CA:1992, 116, 82224.
9. A. Al-Shaar, D. Gilmour, D. Lythoe, I. McClenaghan, C. Ramsden, J. Chem. Soc., Perkin Trans. 1 1992, 2779.