Isocyanates, Part 2.7: Synthesis of Symmetrical and Unsymmetrical Ureas by DMAP-Catalyzed Reaction of Alkyl- and Arylamines with Di-tert-butyldicarbonate

Synlett

Volumn 1996, Issue 6, 1996, Pages 502-504

  Knölker, Hans Joachim ^a   Braxmeier, Tobias ^a   Schlechtingen, Georg ^a  

^a UNIVERSITY OF KARLSRUHE   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

EID: 0040935404     PISSN: 09365214     EISSN: None     Source Type: Journal    
DOI: 10.1055/s-1996-5472     Document Type: Article

References (31)

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24. 13C-NMR, MS). The melting points of the known N,N′-disubstituted ureas (2a, 2e, 2f, 2g, 4a, and 4b) were in agreement with those reported in the literature: A. Dondoni, G. Barbaro, A. Battaglia, J. Org. Chem. 1977, 42, 3372; G. Hagelloch, Chem. Ber. 1950, 83, 258; R. A. Franz, F. Applegath, F. V. Morriss, F. Baiocchi, C. Bolze, J. Org. Chem. 1961, 26, 3306; R. A. Franz, F. Applegath, F. V. Morriss, F. Baiocchi, C. Bolze, J. Org. Chem. 1961, 26, 3309.
25. 13C-NMR, MS). The melting points of the known N,N′-disubstituted ureas (2a, 2e, 2f, 2g, 4a, and 4b) were in agreement with those reported in the literature: A. Dondoni, G. Barbaro, A. Battaglia, J. Org. Chem. 1977, 42, 3372; G. Hagelloch, Chem. Ber. 1950, 83, 258; R. A. Franz, F. Applegath, F. V. Morriss, F. Baiocchi, C. Bolze, J. Org. Chem. 1961, 26, 3306; R. A. Franz, F. Applegath, F. V. Morriss, F. Baiocchi, C. Bolze, J. Org. Chem. 1961, 26, 3309.
26. 13C-NMR, MS). The melting points of the known N,N′-disubstituted ureas (2a, 2e, 2f, 2g, 4a, and 4b) were in agreement with those reported in the literature: A. Dondoni, G. Barbaro, A. Battaglia, J. Org. Chem. 1977, 42, 3372; G. Hagelloch, Chem. Ber. 1950, 83, 258; R. A. Franz, F. Applegath, F. V. Morriss, F. Baiocchi, C. Bolze, J. Org. Chem. 1961, 26, 3306; R. A. Franz, F. Applegath, F. V. Morriss, F. Baiocchi, C. Bolze, J. Org. Chem. 1961, 26, 3309.
27. 13C-NMR, MS). The melting points of the known N,N′-disubstituted ureas (2a, 2e, 2f, 2g, 4a, and 4b) were in agreement with those reported in the literature: A. Dondoni, G. Barbaro, A. Battaglia, J. Org. Chem. 1977, 42, 3372; G. Hagelloch, Chem. Ber. 1950, 83, 258; R. A. Franz, F. Applegath, F. V. Morriss, F. Baiocchi, C. Bolze, J. Org. Chem. 1961, 26, 3306; R. A. Franz, F. Applegath, F. V. Morriss, F. Baiocchi, C. Bolze, J. Org. Chem. 1961, 26, 3309.
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30. B. K. Trivedi, A. Holmes, T. L. Stoeber, C. J. Blankley, W. H. Roark, J. A. Picard, M. K. Shaw, A. D. Essenburg, R. L. Stanfield, B. R. Krause, J. Med. Chem. 1993, 36, 3300; B. K. Trivedi, T. Stoeber Purchase, A. Holmes, C. E. Augelli-Szafran, A. D. Essenburg, K. L. Hamelehle, R. L. Stanfield, R. F. Bousley, B. R. Krause, J. Med. Chem. 1994, 37, 1652.
31. 2O, r. t. (overall yield: 86%).