Contribution of the hydrogen-bond network involving a tyro sine triad in the active site to the structure and function of a highly proficient ketosteroid isomerase from Pseudomonas putida biotype B

Biochemistry

Volumn 39, Issue 16, 2000, Pages 4581-4589

  Kim, Do Hyung ^a   Jang, Do Soo ^a   Nam, Gyu Hyun ^a   Choi, Gildon ^a   Kim, Jeong Sun ^a   Ha, Nam Chul ^a   Kim, Min Sung ^a   Oh, Byung Ha ^a   Choi, Kwan Yong ^a  

^a Pohang University of Science and Technology (POSTECH)   (South Korea)

Author keywords

[No Author keywords available]

Indexed keywords

STEROID DELTA ISOMERASE;

ARTICLE; ENZYME ACTIVE SITE; ENZYME STABILITY; HYDROGEN BOND; NONHUMAN; PRIORITY JOURNAL; PSEUDOMONAS PUTIDA; STRUCTURE ACTIVITY RELATION;

AMINO ACID SUBSTITUTION; BINDING SITES; CATALYSIS; CIRCULAR DICHROISM; CRYSTALLOGRAPHY, X-RAY; ENZYME STABILITY; HYDROGEN BONDING; ISOMERISM; KINETICS; MODELS, MOLECULAR; MUTATION; PROTEIN DENATURATION; PROTEIN STRUCTURE, SECONDARY; PSEUDOMONAS PUTIDA; SOLVENTS; STEROID ISOMERASES; STRUCTURE-ACTIVITY RELATIONSHIP; THERMODYNAMICS; TYROSINE; UREA;

FELIS CATUS; PSEUDOMONAS; PSEUDOMONAS PUTIDA; TYRO;

EID: 0040777049     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi992119u     Document Type: Article

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