Regulation of the expression and function of glucose transporter-1 by TGF-β1 and high glucose in mesangial cells

Chinese Medical Journal

Volumn 113, Issue 6, 2000, Pages 508-513

  Zhang, Jing ^a   Liu, Zhihong H ^a   Liu, Hao ^a   Li, Yingjian J ^a   Li, Leishi S ^a,b  

^a MEDICAL SCHOOL OF NANJING UNIVERSITY   (China)

^b JINLING HOSPITAL   (China)

Author keywords

Diabetic nephropathy; Glucose transporter 1; Hyperglycemia; Mesangial cell; TGF 1

Indexed keywords

DEOXYGLUCOSE; GLUCOSE; GLUCOSE TRANSPORTER; GLUCOSE TRANSPORTER 1; MESSENGER RNA; SLC2A1 PROTEIN, MOUSE; TRANSFORMING GROWTH FACTOR BETA;

ANIMAL; ARTICLE; C57BL MOUSE; CELL LINE; CYTOLOGY; DIABETIC NEPHROPATHY; GENETICS; MESANGIUM; METABOLISM; MOUSE; PHYSIOLOGY;

ANIMALS; CELL LINE; DEOXYGLUCOSE; DIABETIC NEPHROPATHIES; GLOMERULAR MESANGIUM; GLUCOSE; GLUCOSE TRANSPORTER TYPE 1; MICE; MICE, INBRED C57BL; MONOSACCHARIDE TRANSPORT PROTEINS; RNA, MESSENGER; TRANSFORMING GROWTH FACTOR BETA;

EID: 0040518368     PISSN: 03666999     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (23)

1. Reichard P, Nilsson BY, Rosenovist U. The effect of long-term intensive insulin treatment on the development of microvascular complication of diabetes mellitus. N Engl J Med 1993;329:304-309.
2. UKPDS group. Intensive blood-glucose control with sulphonylureas or insulin compared with conventional treatment and risk of complications in patients with type 2 diabetes (UKPDS 33). Lancet 1998;352:837-853.
3. Fioretto P, Steffes MW, Sutherland DER, et al. Reversal of lesions of diabetic nephropathy after pancreas transplantation. N Engl J Med 1998;339:69-75.
4. Pugliese G, Pricci F, Pesce C, et al. Early, but not advanced, glomerulopathy is reversed by pancreatic islet transplants in experimental diabetic rats. Diabetes 1997;46:1198-1206.
5. Heilig CW, Concepcion LA, Riser BL, et al. Overexpression of glucose transporters in rat mesangial cells cultured in a normal glucose milieu mimics diabetic phenotype. J Clin Invest 1995;96:1802-1814.
6. Heilig CW, Brosius FC, Henry DN. Glucose transporters of the glomerulus and the implications for diabetic nephropathy. Kidney Int 1997;52:S91-S99.
7. Kaiser N, Sasson S, Feener EP, et al. Differential regulation of glucose transport and transporters by glucose in vascular endothelial and smooth muscle cells. Diabetes 1993;42:80-89.
8. Kahn BB. Facilitative glucose transporters: regulatory mechanism and dysregulation in diabetes. J Clin Invest 1992;89:1367-1374.
9. Heilig CW, Liu Y, England RL, et al. D-Glucose stimulates mesangial cell GLUT1 expression and basal and IGF-I-sensitive glucose uptake in rat mesangial cells. Diabetes 1997;46:1030-1039.
10. +-coupled and facilitative transporters. Diabetologia 1995;38:291-297.
11. Cortes P, Riser BL, Asano K, et al. Effects of oral antihyperglycemic agents on extracellular matrix synthesis by mesangial cells. Kidney Int 1998;54:1985-1998.
12. Ziyadeh FN, Han DC. Involvement of transforming growth factor-β and its receptors in the pathogenesis of diabetic nephropathy. Kidney Int 1997;60:S7-S11.
13. Kitagawa T, Mtsuko M, Akamatsu Y. Transforming growth factor-β1 stimulates glucose uptake and the expression of glucose transporter mRNA in quiescent swiss mouse 3T3 cells. J Biol Chem 1991;266:18066-18071.
14. Masumi A, Akamatsu Y, Kitagawa T. Modulation of the synthesis and glycosylation of the glucose transporter protein by transforming growth factor-α1 in Swiss 3T3 fibroblasts. Biochim Biophys Acta 1993;1145:227-234.
15. Chin E, Zamah AM, Landau D, et al. Changes in facilitative glucose transporter messenger ribonucleic acid levels in the diabetic rat kidney. Endocrinology 1997;138:1267-1275.
16. Inoki K, Haneda M, Maeda S, et al. TGF-β1 stimulates glucose uptake by enhancing GLUT1 expression in mesangial cells. Kidney Int 1999;55:1704-1712.
17. Ziyadeh FN, Sharma K, M Ericksen, et al. Stimulation of collagen gene expression and protein synthesis in murine mesangial cells by high glucose is mediated by autocrine activation of transforming growth factor β. J Clin Invest 1994;93:536-542.
18. Border WA, Noble NA. TGFβ in kidney fibrosis: a target for gene therapy. Kidney Int 1997;51:1388-1396.
19. Roy S, Sala Roberto, Cagliero E, et al. Overexpression of fibronectin induced by diabetes or high glucose: phenomenon with a memory. Proc Natl Acad Sci U S A 1990;87:404-408.
20. Kim SJ, Denhez F, Kim KY, et al. Activation of the second promoter of the transforming growth factor-beta 1 gene by transforming growth factor-beta 1 and phorbol ester occurs through the same target sequences. J Biol Chem 1989;264:19373-19378.
21. Kreisberg JI, Garoni JA, Radnik R, et al. High glucose and TGF beta 1 stimulate fibronectin gene expression through a cAMP response element. Kidney Int 1994;46:1019-1024.
22. Murakami T, Nishiyama T, Shirotani T, et al. Identification of two enhancer elements in the gene encoding the type 1 glucose transporter from the mouse which are responsive to serum, growth factor, and oncogenes. J Biol Chem 1992;267:9300-9306.
23. Asano T, Katagiri H, Takata K, et al. The role of N-glycosylation of GLUT1 for glucose transport activity. J Biol Chem 1991;266:24632-24636.