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Volumn 257, Issue 2, 1996, Pages 246-264

Interactions of INS (CRS) elements and the splicing machinery regulate the production of Rev-responsive mRNAs

Author keywords

INS (CRS) elements; Rev; Rev response element (RRE); RNA binding proteins; RNA splicing

Indexed keywords

BETA GLOBIN; GAG PROTEIN; GRANULOCYTE MACROPHAGE COLONY STIMULATING FACTOR; MESSENGER RNA; MESSENGER RNA PRECURSOR; NUCLEAR FACTOR; POL PROTEIN; REV PROTEIN;

EID: 0040282093     PISSN: 00222836     EISSN: None     Source Type: Journal    
DOI: 10.1006/jmbi.1996.0160     Document Type: Article
Times cited : (49)

References (82)
  • 1
    • 0022495870 scopus 로고
    • Production of acquired immunodeficiency syndrome-associated retrovirus in human and nonhuman cells transfected with an infectious molecular clone
    • Adachi, A., Gendelman, H. E., Koenig, S., Folks, T., Willey R., Rabson, A. & Martin, M. A. (1986). Production of acquired immunodeficiency syndrome-associated retrovirus in human and nonhuman cells transfected with an infectious molecular clone. J. Virol. 59, 284-291.
    • (1986) J. Virol. , vol.59 , pp. 284-291
    • Adachi, A.1    Gendelman, H.E.2    Koenig, S.3    Folks, T.4    Willey, R.5    Rabson, A.6    Martin, M.A.7
  • 2
    • 0028303171 scopus 로고
    • Presence of negative and positive cis-acting RNA splicing elements within and flanking the first tat coding exon of human immunodeficiency virus type 1
    • Amendt, B. A., Hesslein, D., Chang, L.-J. & Stoltzfus, C. M. (1994). Presence of negative and positive cis-acting RNA splicing elements within and flanking the first tat coding exon of human immunodeficiency virus type 1. Mol. Cell Biol. 14, 3960-3970.
    • (1994) Mol. Cell Biol. , vol.14 , pp. 3960-3970
    • Amendt, B.A.1    Hesslein, D.2    Chang, L.-J.3    Stoltzfus, C.M.4
  • 3
    • 0029025083 scopus 로고
    • Presence of exon splicing silencers within human immunodeficiency virus type 1 tat exon 2 and tat-rev exon 3: Evidence for inhibition mediated by cellular factors
    • Amendt, B. A., Si, Z.-H. & Stoltzfus, C. M. (1995). Presence of exon splicing silencers within human immunodeficiency virus type 1 tat exon 2 and tat-rev exon 3: evidence for inhibition mediated by cellular factors. Mol. Cell Biol. 15, 4606-4615.
    • (1995) Mol. Cell Biol. , vol.15 , pp. 4606-4615
    • Amendt, B.A.1    Si, Z.-H.2    Stoltzfus, C.M.3
  • 4
    • 0025171041 scopus 로고
    • Characterization and expression of novel singly spliced RNA species of human immunodeficiency virus type 1
    • Arrigo, S. J., Wietsman, S., Zack, J. A. & Chen, I. S. Y. (1990). Characterization and expression of novel singly spliced RNA species of human immunodeficiency virus type 1. J. Virol. 64, 4585-4588.
    • (1990) J. Virol. , vol.64 , pp. 4585-4588
    • Arrigo, S.J.1    Wietsman, S.2    Zack, J.A.3    Chen, I.S.Y.4
  • 5
    • 0029053592 scopus 로고
    • The human immunodeficiency virus type 1 Rev protein and the Rev-response element counteract the effect of an inhibitory 5′ splice site in a 3′ untranslated region
    • Barksdale, S. K. & Baker, C. C. (1995). The human immunodeficiency virus type 1 Rev protein and the Rev-response element counteract the effect of an inhibitory 5′ splice site in a 3′ untranslated region. Mol. Cell Biol. 15, 2962-2971.
    • (1995) Mol. Cell Biol. , vol.15 , pp. 2962-2971
    • Barksdale, S.K.1    Baker, C.C.2
  • 6
    • 0026045893 scopus 로고
    • HIV-1 Rev regulation involves recognition of non-Watson-Crick base-pairs in viral RNA
    • Bartel, D. P., Zapp, M. L., Green, M. R. & Szostak, J. W. (1991). HIV-1 Rev regulation involves recognition of non-Watson-Crick base-pairs in viral RNA. Cell, 67, 529-536.
    • (1991) Cell , vol.67 , pp. 529-536
    • Bartel, D.P.1    Zapp, M.L.2    Green, M.R.3    Szostak, J.W.4
  • 7
    • 0028883786 scopus 로고
    • Polypyrimidine tract-binding protein and heterogeneous nuclear ribonucleoprotein A1 bind to human T-cell leukemia virus type 2 RNA regulatory elements
    • Black, A. C., Luo, J., Watanabe, C., Chun, S., Bakker, A., Fraser, J. K., Morgan, J. P. & Rosenblatt, J. D. (1995). Polypyrimidine tract-binding protein and heterogeneous nuclear ribonucleoprotein A1 bind to human T-cell leukemia virus type 2 RNA regulatory elements. J. Virol. 69, 6852-6858.
    • (1995) J. Virol. , vol.69 , pp. 6852-6858
    • Black, A.C.1    Luo, J.2    Watanabe, C.3    Chun, S.4    Bakker, A.5    Fraser, J.K.6    Morgan, J.P.7    Rosenblatt, J.D.8
  • 8
    • 0029149833 scopus 로고
    • Identification of a novel cellular co-factor for the Rev/Rex class of retroviral regulatory proteins
    • Bogerd, H. P., Fridell, R. A., Madore, S. & Cullen, B. R. (1995). Identification of a novel cellular co-factor for the Rev/Rex class of retroviral regulatory proteins. Cell, 82, 485-494.
    • (1995) Cell , vol.82 , pp. 485-494
    • Bogerd, H.P.1    Fridell, R.A.2    Madore, S.3    Cullen, B.R.4
  • 9
    • 0027955795 scopus 로고
    • A small element from the Mason-Pfizer monkey virus genome makes human immunodeficiency virus type 1 expression and replication Rev-independent
    • Bray, M., Prasad, S., Dubay J. W., Hunter, E., Jeang, K.-T., Rekosh, D. & Hammarskjöld, M.-L. (1994). A small element from the Mason-Pfizer monkey virus genome makes human immunodeficiency virus type 1 expression and replication Rev-independent. Proc. Natl Acad. Sci. USA, 91, 1256-1260.
    • (1994) Proc. Natl Acad. Sci. USA , vol.91 , pp. 1256-1260
    • Bray, M.1    Prasad, S.2    Dubay, J.W.3    Hunter, E.4    Jeang, K.-T.5    Rekosh, D.6    Hammarskjöld, M.-L.7
  • 10
    • 0027979089 scopus 로고
    • A cis-acting repressive sequence that overlaps the Rev-responsive element of human immunodeficiency virus type 1 regulates nuclear retention of env mRNAs independently of known splice signals
    • Brighty, D. W. & Rosenberg, M. (1994). A cis-acting repressive sequence that overlaps the Rev-responsive element of human immunodeficiency virus type 1 regulates nuclear retention of env mRNAs independently of known splice signals. Proc. Natl Acad. Sci. USA, 91, 8314-8318.
    • (1994) Proc. Natl Acad. Sci. USA , vol.91 , pp. 8314-8318
    • Brighty, D.W.1    Rosenberg, M.2
  • 11
    • 0023790358 scopus 로고
    • Comparison of intron-dependent and intron-independent gene expression
    • Buchman, A. R. & Berg, P. (1988). Comparison of intron-dependent and intron-independent gene expression. Mol. Cell Biol. 8, 4395-4405.
    • (1988) Mol. Cell Biol. , vol.8 , pp. 4395-4405
    • Buchman, A.R.1    Berg, P.2
  • 12
    • 0024853361 scopus 로고
    • Regulation by HIV Rev depends upon recognition of splice site
    • Chang, D. A. & Sharp, P. A. (1989). Regulation by HIV Rev depends upon recognition of splice site. Cell, 59, 789-795.
    • (1989) Cell , vol.59 , pp. 789-795
    • Chang, D.A.1    Sharp, P.A.2
  • 13
    • 0026459943 scopus 로고
    • Two cellular proteins bind specifically to a purine-rich sequence necessary for the destabilization function of a c-fos protein-coding region determinant of mRNA instability Mol
    • Chen, C.-Y. A., You, Y. & Shyu, A.-B. (1992). Two cellular proteins bind specifically to a purine-rich sequence necessary for the destabilization function of a c-fos protein-coding region determinant of mRNA instability Mol. Cell Biol. 12, 5748-5757.
    • (1992) Cell Biol. , vol.12 , pp. 5748-5757
    • Chen, C.-Y.A.1    You, Y.2    Shyu, A.-B.3
  • 14
    • 0023277545 scopus 로고
    • Single-step method of RNA isolation by acid guanidinium thiocyanatephenol-chloroform extraction
    • Chomczynski, P. & Sacchi, N. (1987). Single-step method of RNA isolation by acid guanidinium thiocyanatephenol-chloroform extraction. Anal. Biochem. 162, 156-159.
    • (1987) Anal. Biochem. , vol.162 , pp. 156-159
    • Chomczynski, P.1    Sacchi, N.2
  • 15
    • 0025017326 scopus 로고
    • Specific interaction of the human immuodeficiency virus Rev protein with a structured region in the env mRNA
    • Cochrane, A. W., Chen, C.-H. & Rosen, C. A. (1990a). Specific interaction of the human immuodeficiency virus Rev protein with a structured region in the env mRNA. Proc. Natl Acad. Sci. USA, 87, 1198-1202.
    • (1990) Proc. Natl Acad. Sci. USA , vol.87 , pp. 1198-1202
    • Cochrane, A.W.1    Chen, C.-H.2    Rosen, C.A.3
  • 16
    • 0025141758 scopus 로고
    • Identification of sequences important in the nucleolar localization of human immunodeficiency virus Rev: Relevance of nucleolar localization to function
    • Cochrane, A. W., Perkins, A. & Rosen, C. A. (1990b). Identification of sequences important in the nucleolar localization of human immunodeficiency virus Rev: relevance of nucleolar localization to function. J. Virol. 64, 881-885.
    • (1990) J. Virol. , vol.64 , pp. 881-885
    • Cochrane, A.W.1    Perkins, A.2    Rosen, C.A.3
  • 17
    • 0026048745 scopus 로고
    • Identification and characterization of intragenic sequences which repress human immunodeficiency virus structural gene expression
    • Cochrane, A. W., Jones, K. S., Beidas, S., Dillon, P. J., Skalka, A. M. & Rosen, C. A. (1991). Identification and characterization of intragenic sequences which repress human immunodeficiency virus structural gene expression. J. Virol. 65, 5305-5313.
    • (1991) J. Virol. , vol.65 , pp. 5305-5313
    • Cochrane, A.W.1    Jones, K.S.2    Beidas, S.3    Dillon, P.J.4    Skalka, A.M.5    Rosen, C.A.6
  • 18
    • 0024836618 scopus 로고
    • Specific binding of HIV-1 recombinant Rev protein to the Rev-responsive element in vitro
    • Daly, T. J., Cook, K. S., Gary, G. S., Maione, T. E. & Rusche, J. R. (1989). Specific binding of HIV-1 recombinant Rev protein to the Rev-responsive element in vitro. Nature, 342, 816-819.
    • (1989) Nature , vol.342 , pp. 816-819
    • Daly, T.J.1    Cook, K.S.2    Gary, G.S.3    Maione, T.E.4    Rusche, J.R.5
  • 19
    • 0024846372 scopus 로고
    • Functional analysis of CAR, the target sequence for the Rev protein of HIV-1
    • Dayton, E. T., Powell, D. M. & Dayton, A. I. (1989). Functional analysis of CAR, the target sequence for the Rev protein of HIV-1. Science, 246, 1625-1629.
    • (1989) Science , vol.246 , pp. 1625-1629
    • Dayton, E.T.1    Powell, D.M.2    Dayton, A.I.3
  • 21
    • 0024382763 scopus 로고
    • The rev gene product of the human immunodeficiency virus affects envelope specific RNA localization
    • Emerman, M., Vazeaux, R. & Peden, K. (1989). The rev gene product of the human immunodeficiency virus affects envelope specific RNA localization. Cell, 57, 1155-1165.
    • (1989) Cell , vol.57 , pp. 1155-1165
    • Emerman, M.1    Vazeaux, R.2    Peden, K.3
  • 22
    • 0022553463 scopus 로고
    • HTLV-III expression and production involve complex regulation at the levels of splicing and translation of viral RNA
    • Feinberg, M. B., Jarrett, R. F., Aldovini, A., Gallo, R. C. & Wong-Staal, F. (1986). HTLV-III expression and production involve complex regulation at the levels of splicing and translation of viral RNA. Cell, 46, 807-817.
    • (1986) Cell , vol.46 , pp. 807-817
    • Feinberg, M.B.1    Jarrett, R.F.2    Aldovini, A.3    Gallo, R.C.4    Wong-Staal, F.5
  • 24
    • 0027981916 scopus 로고
    • Evidence that HIV-1 Rev directly promotes the nuclear export of unspliced RNA
    • Fischer, U., Meyer, S., Teufel, M., Heckel, C., Lührmann, R. & Rautmann, G. (1994). Evidence that HIV-1 Rev directly promotes the nuclear export of unspliced RNA. EMBO J. 13, 4105-4112.
    • (1994) EMBO J. , vol.13 , pp. 4105-4112
    • Fischer, U.1    Meyer, S.2    Teufel, M.3    Heckel, C.4    Lührmann, R.5    Rautmann, G.6
  • 25
    • 0029130169 scopus 로고
    • The HIV-1 Rev activation domain is a nuclear export signal that accesses an export pathway used by specific cellular RNAs
    • Fischer, U., Huber, J., Boelens, W. C., Mattaj, I. W. & Lührmann, R. (1995). The HIV-1 Rev activation domain is a nuclear export signal that accesses an export pathway used by specific cellular RNAs. Cell, 82, 475-483.
    • (1995) Cell , vol.82 , pp. 475-483
    • Fischer, U.1    Huber, J.2    Boelens, W.C.3    Mattaj, I.W.4    Lührmann, R.5
  • 26
    • 0029098538 scopus 로고
    • A human nucleoporin-like protein that specifically interacts with HIV Rev
    • Fritz, C. C., Zapp, M. L. & Green, M. R. (1995). A human nucleoporin-like protein that specifically interacts with HIV Rev. Nature, 376, 530-533.
    • (1995) Nature , vol.376 , pp. 530-533
    • Fritz, C.C.1    Zapp, M.L.2    Green, M.R.3
  • 27
    • 0020531610 scopus 로고
    • High efficiency DNA-mediated transformation of primate cells
    • Gorman, C. M., Padmanabliam, R. & Howard, B. H. (1983). High efficiency DNA-mediated transformation of primate cells. Science, 221, 551-553.
    • (1983) Science , vol.221 , pp. 551-553
    • Gorman, C.M.1    Padmanabliam, R.2    Howard, B.H.3
  • 28
    • 0024590032 scopus 로고
    • The Rev/Art protein of human immunodeficiency virus type 1 affects viral mRNA and protein expression via a cis-acting sequence in the env region
    • Hadzopoulou-Cladaras, M., Felber, B. K., Cladaras, C., Athanassopoulos, A., Tse, A. & Pavlakis, G. N. (1989). The Rev/Art protein of human immunodeficiency virus type 1 affects viral mRNA and protein expression via a cis-acting sequence in the env region. J. Virol. 63, 1265-1274.
    • (1989) J. Virol. , vol.63 , pp. 1265-1274
    • Hadzopoulou-Cladaras, M.1    Felber, B.K.2    Cladaras, C.3    Athanassopoulos, A.4    Tse, A.5    Pavlakis, G.N.6
  • 29
  • 30
    • 0028044759 scopus 로고
    • Human immunodeficiency virus env expression becomes rev-independent if the env region is not defined as an intron
    • Hammarskjöld, M.-L., Li, H., Rekosh, D. & Prasad, S. (1994). Human immunodeficiency virus env expression becomes rev-independent if the env region is not defined as an intron. J. Virol. 68, 951-958.
    • (1994) J. Virol. , vol.68 , pp. 951-958
    • Hammarskjöld, M.-L.1    Li, H.2    Rekosh, D.3    Prasad, S.4
  • 31
    • 0025166385 scopus 로고
    • HIV-1 regulator of virion expression (Rev) protein binds to an RNA stem-loop structure located within the Rev-response element region
    • Heaphy S., Dingwall, C., Ernberg, I., Gait, M. J., Green, S. M., Karn, J., Lowe, A. D., Singh, M. & Skinner, M. A. (1990). HIV-1 regulator of virion expression (Rev) protein binds to an RNA stem-loop structure located within the Rev-response element region. Cell, 60, 685-693.
    • (1990) Cell , vol.60 , pp. 685-693
    • Heaphy, S.1    Dingwall, C.2    Ernberg, I.3    Gait, M.J.4    Green, S.M.5    Karn, J.6    Lowe, A.D.7    Singh, M.8    Skinner, M.A.9
  • 32
    • 0025882673 scopus 로고
    • Human imunodeficiency virus type 1 regulator of virion expression, Rev, forms nucleoprotein filaments after binding to a purine-rich "bubble" located within the rev-responsive region of viral RNA
    • Heaphy, S., Finch, J. T., Gait, M. J., Karn, J. & Singh, M. (1991). Human imunodeficiency virus type 1 regulator of virion expression, Rev, forms nucleoprotein filaments after binding to a purine-rich "bubble" located within the rev-responsive region of viral RNA. Proc. Natl Acad. Sci. USA, 88, 7366-7370.
    • (1991) Proc. Natl Acad. Sci. USA , vol.88 , pp. 7366-7370
    • Heaphy, S.1    Finch, J.T.2    Gait, M.J.3    Karn, J.4    Singh, M.5
  • 33
    • 0026089413 scopus 로고
    • Minimal Rev-response element for type 1 human immuodeficiency virus
    • Huang, X., Hope, T. J., Bond, B. L., McDonald, D., Grahl, K. & Parslow, T. G. (1991). Minimal Rev-response element for type 1 human immuodeficiency virus. J. Virol. 65, 2131-2134.
    • (1991) J. Virol. , vol.65 , pp. 2131-2134
    • Huang, X.1    Hope, T.J.2    Bond, B.L.3    McDonald, D.4    Grahl, K.5    Parslow, T.G.6
  • 34
    • 0027104999 scopus 로고
    • Recognition of the high affinity binding site in Rev-response element RNA by the human immunodeficiency virus type-1 Rev protein
    • Iwai, S., Pritchard, C., Mann, D. A., Karn, J. & Gait, M. J. (1992). Recognition of the high affinity binding site in Rev-response element RNA by the human immunodeficiency virus type-1 Rev protein. Nucl. Acids Res. 20, 6465-6472.
    • (1992) Nucl. Acids Res. , vol.20 , pp. 6465-6472
    • Iwai, S.1    Pritchard, C.2    Mann, D.A.3    Karn, J.4    Gait, M.J.5
  • 35
    • 0027973040 scopus 로고
    • The human immunodeficiency virus type-1 Rev protein shuttles between the cytoplasm and nuclear compartments
    • Kalland, K.-H., Szilvay A. M., Brokstad, K. A., Sætrevik, W. & Haukenes, G. (1994). The human immunodeficiency virus type-1 Rev protein shuttles between the cytoplasm and nuclear compartments. Mol. Cell Biol. 14, 7436-7444.
    • (1994) Mol. Cell Biol. , vol.14 , pp. 7436-7444
    • Kalland, K.-H.1    Szilvay, A.M.2    Brokstad, K.A.3    Sætrevik, W.4    Haukenes, G.5
  • 36
    • 0023770974 scopus 로고
    • Cis-acting intron mutations that affect the efficiency of avian retroviral RNA splicing: Implication for mechanisms of control
    • Katz, R. A., Kotler, M. & Skalka, A. M. (1988). Cis-acting intron mutations that affect the efficiency of avian retroviral RNA splicing: implication for mechanisms of control. J. Virol. 62, 2686-2695.
    • (1988) J. Virol. , vol.62 , pp. 2686-2695
    • Katz, R.A.1    Kotler, M.2    Skalka, A.M.3
  • 37
    • 0027283983 scopus 로고
    • The basic domain of rev from human immunodeficiency virus type 1 specifically blocks the entry of U4/U6-U5 small nuclear ribonucleoprotein in spliceosome assembly
    • Kjems, J. & Sharp, P. A. (1993). The basic domain of rev from human immunodeficiency virus type 1 specifically blocks the entry of U4/U6-U5 small nuclear ribonucleoprotein in spliceosome assembly. J. Virol. 67, 4769-4776.
    • (1993) J. Virol. , vol.67 , pp. 4769-4776
    • Kjems, J.1    Sharp, P.A.2
  • 38
    • 0025940429 scopus 로고
    • Specific regulation of mRNA splicing in vitro by a peptide from HIV-1 Rev
    • Kjems, J., Frankel, A. D. & Sharp, P. A. (1991). Specific regulation of mRNA splicing in vitro by a peptide from HIV-1 Rev. Cell, 67, 169-178.
    • (1991) Cell , vol.67 , pp. 169-178
    • Kjems, J.1    Frankel, A.D.2    Sharp, P.A.3
  • 39
    • 0026540537 scopus 로고
    • Specific binding of a basic peptide from HIV-1 Rev
    • Kjems, J., Calnan, B. J., Frankel, A. D. & Sharp, P. A. (1992). Specific binding of a basic peptide from HIV-1 Rev. EMBO J. 11, 1119-1129.
    • (1992) EMBO J. , vol.11 , pp. 1119-1129
    • Kjems, J.1    Calnan, B.J.2    Frankel, A.D.3    Sharp, P.A.4
  • 40
    • 0029142841 scopus 로고
    • HnRNP L binds a cis-acting RNA sequence element that enables intron-independent gene expression
    • Liu, X. & Mertz, J. E. (1995). HnRNP L binds a cis-acting RNA sequence element that enables intron-independent gene expression. Genes Dev. 9, 1766-1780.
    • (1995) Genes Dev. , vol.9 , pp. 1766-1780
    • Liu, X.1    Mertz, J.E.2
  • 41
    • 0025169566 scopus 로고
    • U1 small nuclear RNA plays a direct role in the formation of a Rev-regulated human immunodeficiency virus env mRNA that remains unspliced
    • Lu, X., Heimer, J., Rekosh, D. & Hammarskjöld, M.-L. (1990). U1 small nuclear RNA plays a direct role in the formation of a Rev-regulated human immunodeficiency virus env mRNA that remains unspliced. Proc. Natl Acad. Sci. USA, 87, 7598-7602.
    • (1990) Proc. Natl Acad. Sci. USA , vol.87 , pp. 7598-7602
    • Lu, X.1    Heimer, J.2    Rekosh, D.3    Hammarskjöld, M.-L.4
  • 42
    • 0025983154 scopus 로고
    • Identification of posttranscriptionally active inhibitor sequences in human immunodeficiency virus type 1 RNA: Novel level of gene regulation
    • Maldarelli, F., Martin, M. A. & Strebel, K. (1991). Identification of posttranscriptionally active inhibitor sequences in human immunodeficiency virus type 1 RNA: novel level of gene regulation. J. Virol. 65, 5732-5743.
    • (1991) J. Virol. , vol.65 , pp. 5732-5743
    • Maldarelli, F.1    Martin, M.A.2    Strebel, K.3
  • 43
    • 0025818452 scopus 로고
    • HIV-1 structural gene expression requires the binding of multiple Rev monomers to the viral RRE: Implications for HIV-1 latency
    • Malim, M. H. & Cullen, B. R. (1991). HIV-1 structural gene expression requires the binding of multiple Rev monomers to the viral RRE: implications for HIV-1 latency Cell, 65, 241-248.
    • (1991) Cell , vol.65 , pp. 241-248
    • Malim, M.H.1    Cullen, B.R.2
  • 44
    • 0027434118 scopus 로고
    • Rev and the fate of pre-mRNA in the nucleus: Implications for the regulation of RNA processing in eukaryotes
    • Malim, M. H. & Cullen, B. R. (1993). Rev and the fate of pre-mRNA in the nucleus: Implications for the regulation of RNA processing in eukaryotes. Mol. Cell Biol. 13, 6180-6189.
    • (1993) Mol. Cell Biol. , vol.13 , pp. 6180-6189
    • Malim, M.H.1    Cullen, B.R.2
  • 45
    • 0024382709 scopus 로고
    • Functional dissection of the the HIV-1 Rev trans-activator: Derivation of a trans-dominant repressor of Rev function
    • Malim, M. H., Bohnlein, S., Hauber, J. & Cullen, B. R. (1989a). Functional dissection of the the HIV-1 Rev trans-activator: derivation of a trans-dominant repressor of Rev function. Cell, 58, 205-214.
    • (1989) Cell , vol.58 , pp. 205-214
    • Malim, M.H.1    Bohnlein, S.2    Hauber, J.3    Cullen, B.R.4
  • 46
    • 0024518918 scopus 로고
    • The HIV-1 Rev trans-activator acts through a structured target sequence to activate nuclear export of unspliced viral mRNA
    • Malim, M. H., Hauber, J., Le, S.-Y., Maizel, J. V. & Cullen, B. R. (1989b). The HIV-1 Rev trans-activator acts through a structured target sequence to activate nuclear export of unspliced viral mRNA. Nature, 338, 254-257.
    • (1989) Nature , vol.338 , pp. 254-257
    • Malim, M.H.1    Hauber, J.2    Le, S.-Y.3    Maizel, J.V.4    Cullen, B.R.5
  • 47
    • 0025190644 scopus 로고
    • HIV-1 structural gene expression requires binding of the Rev trans-activator to its RNA target sequence
    • Malim, M. H., Tiley L. S., McCarn, D. F., Rusche, J. R., Hauber, J. & Cullen, B. R. (1990). HIV-1 structural gene expression requires binding of the Rev trans-activator to its RNA target sequence. Cell, 60, 675-683.
    • (1990) Cell , vol.60 , pp. 675-683
    • Malim, M.H.1    Tiley, L.S.2    McCarn, D.F.3    Rusche, J.R.4    Hauber, J.5    Cullen, B.R.6
  • 48
    • 0025766815 scopus 로고
    • Mutational definition of the human immunodeficiency virus type 1 Rev activation domain
    • Malim, M. H., McCarn, D. F., Tiley, L. S. & Cullen, B. R. (1991). Mutational definition of the human immunodeficiency virus type 1 Rev activation domain. J. Virol. 65, 4248-4254.
    • (1991) J. Virol. , vol.65 , pp. 4248-4254
    • Malim, M.H.1    McCarn, D.F.2    Tiley, L.S.3    Cullen, B.R.4
  • 49
    • 0027343111 scopus 로고
    • The acidic activation domain of the Epstein-Barr virus transcription factor R interacts in vitro with both TBP and TFIIB and is cell-specifically potentiated by a proline-rich region
    • Manet, E., Allera, C., Gruffat, H., Mikaélian, I., Rigolet, A. & Sargeant, A. (1993). The acidic activation domain of the Epstein-Barr virus transcription factor R interacts in vitro with both TBP and TFIIB and is cell-specifically potentiated by a proline-rich region. Gene Expression, 3, 49-59.
    • (1993) Gene Expression , vol.3 , pp. 49-59
    • Manet, E.1    Allera, C.2    Gruffat, H.3    Mikaélian, I.4    Rigolet, A.5    Sargeant, A.6
  • 50
    • 0028108364 scopus 로고
    • A molecular rheostat: Co-operative Rev binding to stem I of the Rev-response element modulates human immunodeficiency virus type-1 late gene expression
    • Mann, D. A., Mikaélian, I., Zemmel, R. W., Green, S. M., Lowe, A. D., Kimura, T., Singh, M., Butler, P. J. G., Gait, M. J. & Karn, J. (1994). A molecular rheostat: co-operative Rev binding to stem I of the Rev-response element modulates human immunodeficiency virus type-1 late gene expression. J. Mol. Biol. 241, 193-207.
    • (1994) J. Mol. Biol. , vol.241 , pp. 193-207
    • Mann, D.A.1    Mikaélian, I.2    Zemmel, R.W.3    Green, S.M.4    Lowe, A.D.5    Kimura, T.6    Singh, M.7    Butler, P.J.G.8    Gait, M.J.9    Karn, J.10
  • 51
    • 0026500529 scopus 로고
    • Intronic sequences and 3′ splice sites control Rous sarcoma virus RNA splicing
    • McNally M. T. & Beemon, K. (1992). Intronic sequences and 3′ splice sites control Rous sarcoma virus RNA splicing. J. Virol. 66, 6-11.
    • (1992) J. Virol. , vol.66 , pp. 6-11
    • McNally, M.T.1    Beemon, K.2
  • 52
    • 0025953458 scopus 로고
    • Characterization of Rous sarcoma virus intronic sequences that negatively regulate splicing
    • McNally M. T., Gontarek, R. R. & Beemon, K. (1991). Characterization of Rous sarcoma virus intronic sequences that negatively regulate splicing. Virology, 185, 99-108.
    • (1991) Virology , vol.185 , pp. 99-108
    • McNally, M.T.1    Gontarek, R.R.2    Beemon, K.3
  • 53
    • 0028239268 scopus 로고
    • The HIV-1 Rev trans-activator shuttles between the nucleus and the cytoplasm
    • Meyer, B. E. & Malim, M. H. (1994). The HIV-1 Rev trans-activator shuttles between the nucleus and the cytoplasm. Genes Dev. 8, 1538-1547.
    • (1994) Genes Dev. , vol.8 , pp. 1538-1547
    • Meyer, B.E.1    Malim, M.H.2
  • 54
    • 0026573580 scopus 로고
    • A general and fast method to generate multiple site directed mutations
    • Mikaélian, I. & Sergeant, A. (1992). A general and fast method to generate multiple site directed mutations. Nucl. Acids Res. 20, 376.
    • (1992) Nucl. Acids Res. , vol.20 , pp. 376
    • Mikaélian, I.1    Sergeant, A.2
  • 55
    • 0028222158 scopus 로고
    • Elements distinct from human immunodeficiency virus type 1 splice sites are responsible for the Rev dependence of env mRNA
    • Nasioulas, G., Zolotukhin, A. S., Tabernero, C., Solomin, L., Cunningham, C. P., Pavlakis, G. N. & Felber, B., K. (1994). Elements distinct from human immunodeficiency virus type 1 splice sites are responsible for the Rev dependence of env mRNA. J. Virol. 68, 2986-2993.
    • (1994) J. Virol. , vol.68 , pp. 2986-2993
    • Nasioulas, G.1    Zolotukhin, A.S.2    Tabernero, C.3    Solomin, L.4    Cunningham, C.P.5    Pavlakis, G.N.6    Felber, B.K.7
  • 56
    • 0027137059 scopus 로고
    • The effect of sequences with high AU content on mRNA stability in tobacco
    • Ohme-Takagi, M., Taylor, C. B., Newman, T. C. & Green, P. J. (1993). The effect of sequences with high AU content on mRNA stability in tobacco. Proc. Natl Acad. Sci. USA, 90, 11811-11815.
    • (1993) Proc. Natl Acad. Sci. USA , vol.90 , pp. 11811-11815
    • Ohme-Takagi, M.1    Taylor, C.B.2    Newman, T.C.3    Green, P.J.4
  • 57
    • 0025184516 scopus 로고
    • Interaction of the human immunodeficiency virus type 1 Rev protein with a structured region in env mRNA is dependent on multimer formation mediated through a basic stretch of amino acids
    • Olsen, H. S., Cochrane, A. W., Dillon, P. J., Nalin, C. M. & Rosen, C. A. (1990a). Interaction of the human immunodeficiency virus type 1 Rev protein with a structured region in env mRNA is dependent on multimer formation mediated through a basic stretch of amino acids. Genes Dev. 4, 1357-1364.
    • (1990) Genes Dev. , vol.4 , pp. 1357-1364
    • Olsen, H.S.1    Cochrane, A.W.2    Dillon, P.J.3    Nalin, C.M.4    Rosen, C.A.5
  • 58
    • 0025100771 scopus 로고
    • Secondary structure is the major determinant for interaction of HIV Rev protein with RNA
    • Olsen, H. S., Nelbrock, P., Cohrane, A. W. & Rosen, C. A. (1990b). Secondary structure is the major determinant for interaction of HIV Rev protein with RNA. Science, 247, 845-848.
    • (1990) Science , vol.247 , pp. 845-848
    • Olsen, H.S.1    Nelbrock, P.2    Cohrane, A.W.3    Rosen, C.A.4
  • 59
    • 0028807036 scopus 로고
    • Two strong 5′ splice sites and competing suboptimal 3′ splice sites involved in alternative splicing of human immunodeficiency virus type 1 RNA
    • O'Reilly M. M., McNally M. T. & Beemon, K. L. (1995). Two strong 5′ splice sites and competing suboptimal 3′ splice sites involved in alternative splicing of human immunodeficiency virus type 1 RNA. Virology, 213, 373-385.
    • (1995) Virology , vol.213 , pp. 373-385
    • O'Reilly, M.M.1    McNally, M.T.2    Beemon, K.L.3
  • 60
    • 0029043570 scopus 로고
    • Indentification and mapping of inhibitory sequences in the human immunodeficiency virus type 2 vif gene
    • Reddy T. R., Kraus, G., Suhasini, M., Leavitt, M. C. & Wong-Staal, F. (1995). Indentification and mapping of inhibitory sequences in the human immunodeficiency virus type 2 vif gene. J. Virol. 69, 5167-5170.
    • (1995) J. Virol. , vol.69 , pp. 5167-5170
    • Reddy, T.R.1    Kraus, G.2    Suhasini, M.3    Leavitt, M.C.4    Wong-Staal, F.5
  • 61
    • 0027993696 scopus 로고
    • HIV-1 Rev is capable of shuttling between the nucleus and the cytoplasm
    • Richard, N., Iacampo, S. & Cochrane, A. (1994). HIV-1 Rev is capable of shuttling between the nucleus and the cytoplasm. Virology, 204, 123-131.
    • (1994) Virology , vol.204 , pp. 123-131
    • Richard, N.1    Iacampo, S.2    Cochrane, A.3
  • 62
    • 0025281329 scopus 로고
    • Structure and expression of tat-, rev-, and nef-specific transcripts of human immunodeficiency virus type 1 in infected lymphocytes and macrophages
    • Robert-Guroff, M., Popovic, M., Gartner, S., Markham, P., Gallo, R. C. & Reitz, M. S. (1990). Structure and expression of tat-, rev-, and nef-specific transcripts of human immunodeficiency virus type 1 in infected lymphocytes and macrophages. J. Virol. 64, 3391-3398.
    • (1990) J. Virol. , vol.64 , pp. 3391-3398
    • Robert-Guroff, M.1    Popovic, M.2    Gartner, S.3    Markham, P.4    Gallo, R.C.5    Reitz, M.S.6
  • 64
    • 0025335833 scopus 로고
    • Cloning and functional analysis of multiply spliced mRNA species of human immunodeficiency virus type 1
    • Schwartz, S., Felber, B. K., Benko, D. M., Fenyo, E.-M. & Pavlakis, G. N. (1990a). Cloning and functional analysis of multiply spliced mRNA species of human immunodeficiency virus type 1. J. Virol. 64, 2519-2529.
    • (1990) J. Virol. , vol.64 , pp. 2519-2529
    • Schwartz, S.1    Felber, B.K.2    Benko, D.M.3    Fenyo, E.-M.4    Pavlakis, G.N.5
  • 65
    • 0025131891 scopus 로고
    • Env and Vpu proteins of human immuno-deficiency virus type 1 are produced from multiple bicistronic mRNAs
    • Schwartz, S., Felber, B. K., Fenyo, E.-M. & Pavlakis, G. N. (1990b). Env and Vpu proteins of human immuno-deficiency virus type 1 are produced from multiple bicistronic mRNAs. J. Virol. 64, 5448-5456.
    • (1990) J. Virol. , vol.64 , pp. 5448-5456
    • Schwartz, S.1    Felber, B.K.2    Fenyo, E.-M.3    Pavlakis, G.N.4
  • 66
    • 0026447940 scopus 로고
    • Mutational inactivation of an inhibitory sequence in human immunodeficiency virus type 1 results in Revindependent gag expression
    • Schwartz, S., Campbell, M., Nasioulas, G., Harrison, J., Felber, B. K. & Pavlakis, G. N. (1992a). Mutational inactivation of an inhibitory sequence in human immunodeficiency virus type 1 results in Revindependent gag expression. J. Virol. 66, 7176-7182.
    • (1992) J. Virol. , vol.66 , pp. 7176-7182
    • Schwartz, S.1    Campbell, M.2    Nasioulas, G.3    Harrison, J.4    Felber, B.K.5    Pavlakis, G.N.6
  • 67
    • 0026555177 scopus 로고
    • Distinct RNA sequences in the gag region of human immunodeficiency virus type 1 decrease RNA stability and inhibit expression in the absence of Rev protein
    • Schwartz, S., Felber, B. K. & Pavlakis, G. N. (1992b). Distinct RNA sequences in the gag region of human immunodeficiency virus type 1 decrease RNA stability and inhibit expression in the absence of Rev protein. J. Virol. 66, 150-159.
    • (1992) J. Virol. , vol.66 , pp. 150-159
    • Schwartz, S.1    Felber, B.K.2    Pavlakis, G.N.3
  • 68
    • 0023058975 scopus 로고
    • A conserved AU sequence from the 3′ untranslated region of GM-CSF mRNA mediates selective mRNA degradation
    • Shaw, G. & Kamen, R. (1986). A conserved AU sequence from the 3′ untranslated region of GM-CSF mRNA mediates selective mRNA degradation. Cell, 46, 659-667.
    • (1986) Cell , vol.46 , pp. 659-667
    • Shaw, G.1    Kamen, R.2
  • 69
    • 0022444917 scopus 로고
    • A second post-transcriptional activator gene required for HTLV-III replication
    • Sodroski, J., Goh, W. C., Rosen, C. A., Dayton, A., Terwilliger, E. & Haseltine, W. A. (1986). A second post-transcriptional activator gene required for HTLV-III replication. Nature, 321, 412-417.
    • (1986) Nature , vol.321 , pp. 412-417
    • Sodroski, J.1    Goh, W.C.2    Rosen, C.A.3    Dayton, A.4    Terwilliger, E.5    Haseltine, W.A.6
  • 70
    • 0028316954 scopus 로고
    • The tat-rev intron of human immunodeficiency virus type 1 is inefficiently spliced because of suboptimal signals in the 3′ splice site
    • Staffa, A. & Cochrane, A. (1994). The tat-rev intron of human immunodeficiency virus type 1 is inefficiently spliced because of suboptimal signals in the 3′ splice site. J. Virol. 68, 3071-3079.
    • (1994) J. Virol. , vol.68 , pp. 3071-3079
    • Staffa, A.1    Cochrane, A.2
  • 71
    • 0028999992 scopus 로고
    • Identification of positive and negative splicing regulatory elements within the terminal tat-rev exon of human immunodeficiency virus type 1
    • Staffa, A. & Cochrane, A. (1995). Identification of positive and negative splicing regulatory elements within the terminal tat-rev exon of human immunodeficiency virus type 1. Mol. Cell Biol. 15, 4597-4605.
    • (1995) Mol. Cell Biol. , vol.15 , pp. 4597-4605
    • Staffa, A.1    Cochrane, A.2
  • 72
    • 0027990609 scopus 로고
    • A functional interaction between Rev and yeast pre-mRNA is related to splicing complex formation
    • Stutz, F. & Rosbash, M. (1994). A functional interaction between Rev and yeast pre-mRNA is related to splicing complex formation. EMBO J. 13, 4096-4104.
    • (1994) EMBO J. , vol.13 , pp. 4096-4104
    • Stutz, F.1    Rosbash, M.2
  • 73
    • 0029122732 scopus 로고
    • Identification of a novel nuclear pore-associated protein as a functional target of the HIV-1 Rev protein in yeast
    • Stutz, F., Neville, M. & Rosbach, M. (1995). Identification of a novel nuclear pore-associated protein as a functional target of the HIV-1 Rev protein in yeast. Cell, 82, 495-506.
    • (1995) Cell , vol.82 , pp. 495-506
    • Stutz, F.1    Neville, M.2    Rosbach, M.3
  • 74
    • 0026601935 scopus 로고
    • Identification of a high-affinity RNA-binding site for the human immunodeficiency virus type 1 Rev protein
    • Tiley, L. S., Malim, M. H., Tewary, H. K., Stockley P. G. & Cullen, B. R. (1992). Identification of a high-affinity RNA-binding site for the human immunodeficiency virus type 1 Rev protein. Proc. Natl Acad. Sci. USA, 89, 758-762.
    • (1992) Proc. Natl Acad. Sci. USA , vol.89 , pp. 758-762
    • Tiley, L.S.1    Malim, M.H.2    Tewary, H.K.3    Stockley, P.G.4    Cullen, B.R.5
  • 75
    • 0025756170 scopus 로고
    • A 32-kilodalton protein binds to AU-rich domains in the 3′ untranslated regions of rapidly degraded mRNAs
    • Vakalopoulou, E., Schaack, J. & Shenk, T. (1991). A 32-kilodalton protein binds to AU-rich domains in the 3′ untranslated regions of rapidly degraded mRNAs. Mol. Cell Biol. 11, 3355-3364.
    • (1991) Mol. Cell Biol. , vol.11 , pp. 3355-3364
    • Vakalopoulou, E.1    Schaack, J.2    Shenk, T.3
  • 76
    • 0029130168 scopus 로고
    • Identification of a signal for rapid export of proteins from the nucleus
    • Wen, W., Meinkoth, J. L., Tsien, R. Y. & Taylor, S. S. (1995). Identification of a signal for rapid export of proteins from the nucleus. Cell, 82, 463-473.
    • (1995) Cell , vol.82 , pp. 463-473
    • Wen, W.1    Meinkoth, J.L.2    Tsien, R.Y.3    Taylor, S.S.4
  • 77
    • 0028916872 scopus 로고
    • Nucleocytoplasmic transport of the Rev protein of human immunodeficiency virus type 2 is dependent on the activation domain of the protein
    • Wolff, B., Cohen, G., Hauber, J., Meshcheryakova, D. & Rabeck, C. (1995). Nucleocytoplasmic transport of the Rev protein of human immunodeficiency virus type 2 is dependent on the activation domain of the protein. Exp. Cell Res. 217, 31-41.
    • (1995) Exp. Cell Res. , vol.217 , pp. 31-41
    • Wolff, B.1    Cohen, G.2    Hauber, J.3    Meshcheryakova, D.4    Rabeck, C.5
  • 78
    • 0027160003 scopus 로고
    • Distinct functions of SR proteins in alternative pre-mRNA splicing
    • Zahler, A. M., Neugelauer, K. M., Lane, W. S. & Roth, M. B. (1993). Distinct functions of SR proteins in alternative pre-mRNA splicing. Science, 260, 219-221.
    • (1993) Science , vol.260 , pp. 219-221
    • Zahler, A.M.1    Neugelauer, K.M.2    Lane, W.S.3    Roth, M.B.4
  • 79
    • 0024310483 scopus 로고
    • Sequence-specific binding by the HIV-1 Rev protein
    • Zapp, M. L. & Green, M. R. (1989). Sequence-specific binding by the HIV-1 Rev protein. Nature, 342, 714-716.
    • (1989) Nature , vol.342 , pp. 714-716
    • Zapp, M.L.1    Green, M.R.2
  • 80
    • 0025917131 scopus 로고
    • Oligomerization and RNA binding domains of the type 1 human immunodeficiency virus Rev protein: A dual function for an arginine-rich binding motif
    • Zapp, M. L., Hope, T. J., Parslow, T. G. & Green, M. R. (1991). Oligomerization and RNA binding domains of the type 1 human immunodeficiency virus Rev protein: a dual function for an arginine-rich binding motif. Proc. Natl Acad. Sci. USA, 88, 7734-7738.
    • (1991) Proc. Natl Acad. Sci. USA , vol.88 , pp. 7734-7738
    • Zapp, M.L.1    Hope, T.J.2    Parslow, T.G.3    Green, M.R.4
  • 81
    • 0029933537 scopus 로고    scopus 로고
    • Flexible regions of RNA structure facilitate co-operative Rev assembly on the Rev-response element
    • in press
    • Zemmel, R. W., Kelley A. C., Karn, J., Butler, P. J. G. (1996). Flexible regions of RNA structure facilitate co-operative Rev assembly on the Rev-response element. J. Mol. Biol. in press.
    • (1996) J. Mol. Biol.
    • Zemmel, R.W.1    Kelley, A.C.2    Karn, J.3    Butler, P.J.G.4
  • 82
    • 0028033969 scopus 로고
    • Continuous propogation of RRE(-) and Rev(-)RRE(-) human immunodeficiency virus type 1 molecular clones containing a cis-acting element of simian retrovirus type 1 in human peripheral blood lymphocytes
    • Zolotukhin, A. S., Valentin, A., Pavlakis, G. N. & Felber, B. K. (1994). Continuous propogation of RRE(-) and Rev(-)RRE(-) human immunodeficiency virus type 1 molecular clones containing a cis-acting element of simian retrovirus type 1 in human peripheral blood lymphocytes. J. Virol. 68, 7944-7952.
    • (1994) J. Virol. , vol.68 , pp. 7944-7952
    • Zolotukhin, A.S.1    Valentin, A.2    Pavlakis, G.N.3    Felber, B.K.4


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