Heck Reactions under Microwave Irradiation in Solvent-Free Conditions

Synlett

Volumn 1997, Issue 3, 1997, Pages 269-270

  Díaz Ortiz, Ángel ^a   Prieto, Pilar ^a   Vázquez, Ester ^a  

^a UNIVERSITY OF CASTILLA LA MANCHA   (Spain)

Author keywords

[No Author keywords available]

Indexed keywords

EID: 0040236037     PISSN: 09365214     EISSN: None     Source Type: Journal    
DOI: 10.1055/s-1997-774     Document Type: Article

References (11)

1. Heck, R. F. Org. React. 1982, 27, 345.
2. (a) de Meijere, A.; Meyer, F.E. Angew. Chem. Int. Ed. Engl., 1994, 33, 2379.
3. (b) Cabri, W.; Candiani, I. Acc. Chem. Res., 1995, 28, 2.
4. (a) Caddick, S. Tetrahedron, 1995, 51, 10403.
5. (b) Majetich, G.; Hicks, R. Radiat. Phys. Chem., 1995, 45, 567.
6. Díaz-Ortiz, A.; Díez-Barra, E.; de la Hoz, A.; Prieto, P.; Moreno, A.; Langa, F.; Prangé, T.; Neuman, A. J. Org. Chem., 1995, 60, 4160.
7. (b) Díaz-Ortiz, A.; Prieto, P.; Loupy, A.; Abenhaïm, D. Tetrahedron Lett, 1996, 37, 1695.
8. 4 and the solvent was removed at reduced pressure. The residue was purified by flash column chromatography. Owing to the moderate polarity of some reagents, the irradiated reaction mixture can not reach 150°C teflon vessel must be irradiated inside an alumina bath (25 g) to increase the temperature. Warning: As is typically recommended in microwave chemistry, to prevent explosions the reaction mixture must not exceed 10% in volume of the vessel.
9. 1H-NMR or IR).
10. Voigt, K.; Schick, H.; Meyer, F.E.; de Meijere, A. Synlett, 1994, 189.
11. Deck, H. A.; Heck, R. F. J. Am. Chem. Soc., 1974, 96, 1133.