-
1
-
-
0021904906
-
The molecular mechanism of insulin action
-
Kahn CR (1985) The molecular mechanism of insulin action. Annu Rev Med 36:429-451
-
(1985)
Annu Rev Med
, vol.36
, pp. 429-451
-
-
Kahn, C.R.1
-
2
-
-
0026456964
-
The insulin responsive glucose transporter
-
Birnbaum MJ (1992) The insulin responsive glucose transporter. Int Rev Cytol 137A:239-297
-
(1992)
Int Rev Cytol
, vol.137 A
, pp. 239-297
-
-
Birnbaum, M.J.1
-
3
-
-
0025708167
-
Insulin regulation of the two glucose transporters in 3T3-L1 adipocytes
-
Calderhead DM, Kitagawa K, Tanner LI, Holman GD, Lienhard GE (1990) Insulin regulation of the two glucose transporters in 3T3-L1 adipocytes. J Biol Chem 265:13801-13808
-
(1990)
J Biol Chem
, vol.265
, pp. 13801-13808
-
-
Calderhead, D.M.1
Kitagawa, K.2
Tanner, L.I.3
Holman, G.D.4
Lienhard, G.E.5
-
4
-
-
0024411467
-
The regulation by insulin of glucose transporter gene expression in 3T3 adipocytes
-
Garcia de Herreros A, Birnbaum MJ (1989) The regulation by insulin of glucose transporter gene expression in 3T3 adipocytes. J Biol Chem 264:9885-9890
-
(1989)
J Biol Chem
, vol.264
, pp. 9885-9890
-
-
Garcia De Herreros, A.1
Birnbaum, M.J.2
-
5
-
-
0003618438
-
Differential regulation of two distinct glucose transporter species expressed in 3T3-L1 adipocytes: Effect of chronic insulin and tolbutamide treatment
-
Tordjman KM, Leingang KA, James DE, Mueckler MM (1989) Differential regulation of two distinct glucose transporter species expressed in 3T3-L1 adipocytes: effect of chronic insulin and tolbutamide treatment. Proc Natl Acad Sci USA 86:7761-7765
-
(1989)
Proc Natl Acad Sci USA
, vol.86
, pp. 7761-7765
-
-
Tordjman, K.M.1
Leingang, K.A.2
James, D.E.3
Mueckler, M.M.4
-
6
-
-
0026596043
-
Isoform-specific subcellular targeting of glucose transporters in mouse fibroblasts
-
Hudson AW, Ruiz ML, Birnbaum MJ (1992) Isoform-specific subcellular targeting of glucose transporters in mouse fibroblasts. J Cell Biol 116:785-797
-
(1992)
J Cell Biol
, vol.116
, pp. 785-797
-
-
Hudson, A.W.1
Ruiz, M.L.2
Birnbaum, M.J.3
-
7
-
-
0026561291
-
Expression of the glucose transporter isoform GLUT 4 is insufficient to confer insulin-regulatable hexose uptake to cultured muscle cells
-
Kotliar N, Pilch PF (1992) Expression of the glucose transporter isoform GLUT 4 is insufficient to confer insulin-regulatable hexose uptake to cultured muscle cells. Molec Endocrinol 6:337-345
-
(1992)
Molec Endocrinol
, vol.6
, pp. 337-345
-
-
Kotliar, N.1
Pilch, P.F.2
-
8
-
-
0023188325
-
After insulin binds
-
Rosen OM (1987) After insulin binds. Science 237:1452-1458
-
(1987)
Science
, vol.237
, pp. 1452-1458
-
-
Rosen, O.M.1
-
10
-
-
0025813375
-
Structure of the Insulin Receptor Substrate IRS-1 defines a unique signal transduction protein
-
Sun XJ, Rothenberg P, Kahn CR, Backer JM, Araki E, Wilden PA, Cahill DA, Goldstein BJ, White MF (1991) Structure of the insulin receptor substrate IRS-1 defines a unique signal transduction protein. Nature 352:73-77
-
(1991)
Nature
, vol.352
, pp. 73-77
-
-
Sun, X.J.1
Rothenberg, P.2
Kahn, C.R.3
Backer, J.M.4
Araki, E.5
Wilden, P.A.6
Cahill, D.A.7
Goldstein, B.J.8
White, M.F.9
-
11
-
-
0029148591
-
Role of IRS-2 in insulin and cytokine signalling
-
Sun XJ, Wang L-M, Zhang Y, Yenush L, Myers M, Glasheen E, Lane W, Pierce J, White MF (1995) Role of IRS-2 in insulin and cytokine signalling. Nature 377:173-177
-
(1995)
Nature
, vol.377
, pp. 173-177
-
-
Sun, X.J.1
Wang, L.-M.2
Zhang, Y.3
Yenush, L.4
Myers, M.5
Glasheen, E.6
Lane, W.7
Pierce, J.8
White, M.F.9
-
12
-
-
0028085078
-
The insulin signaling system
-
White MF, Kahn CR (1994) The insulin signaling system. J Biol Chem 269:14
-
(1994)
J Biol Chem
, vol.269
, pp. 14
-
-
White, M.F.1
Kahn, C.R.2
-
13
-
-
0029135003
-
New frontiers in insulin receptor signaling
-
Myers M, White M (1995) New frontiers in insulin receptor signaling. Trends Endocrinol Metab 6:209-215
-
(1995)
Trends Endocrinol Metab
, vol.6
, pp. 209-215
-
-
Myers, M.1
White, M.2
-
14
-
-
0028227166
-
Biochemical mechanisms of insulin resistance
-
Roth RA, Liu F, Chin JE (1994) Biochemical mechanisms of insulin resistance. Hormone Res 41:51-55
-
(1994)
Hormone Res
, vol.41
, pp. 51-55
-
-
Roth, R.A.1
Liu, F.2
Chin, J.E.3
-
15
-
-
0028352860
-
Tyrosine kinase-deficient mutant human insulin receptors (Met1153->11e) overexpressed in transfected rat adipose cells fail to mediate translocation of epitope-tagged GLUT4
-
Quon MJ, Guerre-Millo M, Zarnowski MJ, Butte AJ, Em M, Cushman SW, Taylor SI (1994) Tyrosine kinase-deficient mutant human insulin receptors (Met1153->11e) overexpressed in transfected rat adipose cells fail to mediate translocation of epitope-tagged GLUT4. Proc Nat Acad Sci USA 91:5587-5591
-
(1994)
Proc Nat Acad Sci USA
, vol.91
, pp. 5587-5591
-
-
Quon, M.J.1
Guerre-Millo, M.2
Zarnowski, M.J.3
Butte, A.J.4
Em, M.5
Cushman, S.W.6
Taylor, S.I.7
-
16
-
-
0026744181
-
Regulation of the expression of pp160, a putative insulin receptor signal protein, by insulin, dexamethasone, and 1-methyl-3-iso butylxanthine in 3T3-L1 adipocytes
-
Rice KM, Lienhard GE, Garner CW (1992) Regulation of the expression of pp160, a putative insulin receptor signal protein, by insulin, dexamethasone, and 1-methyl-3-iso butylxanthine in 3T3-L1 adipocytes. J Biol Chem 267:10163-10167
-
(1992)
J Biol Chem
, vol.267
, pp. 10163-10167
-
-
Rice, K.M.1
Lienhard, G.E.2
Garner, C.W.3
-
17
-
-
0028910216
-
Growth hormone stimulates the tyrosine phosphorylation of the insulin receptor substrate-1 and its association with phosphatidylinositol 3-kinase in primary adipocyte
-
Ridderstrale M, Degerman E, Tornqvist H (1995) Growth hormone stimulates the tyrosine phosphorylation of the insulin receptor substrate-1 and its association with phosphatidylinositol 3-kinase in primary adipocyte. J Biol Chem 270:3471-3474
-
(1995)
J Biol Chem
, vol.270
, pp. 3471-3474
-
-
Ridderstrale, M.1
Degerman, E.2
Tornqvist, H.3
-
18
-
-
0028032894
-
Insulin resistance and growth retardation in mice lacking insulin receptor substrate-1
-
Tamemoto H, Kadowaki T, Tobe K, Yagi T, Sakura H, Hayakawa T, Terauchi Y, Ueki K, Kaburagi Y, Satoh S, et al (1994) Insulin resistance and growth retardation in mice lacking insulin receptor substrate-1. Nature 372:182-186
-
(1994)
Nature
, vol.372
, pp. 182-186
-
-
Tamemoto, H.1
Kadowaki, T.2
Tobe, K.3
Yagi, T.4
Sakura, H.5
Hayakawa, T.6
Terauchi, Y.7
Ueki, K.8
Kaburagi, Y.9
Satoh, S.10
-
19
-
-
0028032895
-
Alternative pathway of insulin signalling in mice with targeted disruption of the IRS-1 gene
-
Araki E, Lipes MA, Patti ME, Bruning JC, Haag Br, Johnson RS, Kahn CR (1994) Alternative pathway of insulin signalling in mice with targeted disruption of the IRS-1 gene. Nature 372:186-190
-
(1994)
Nature
, vol.372
, pp. 186-190
-
-
Araki, E.1
Lipes, M.A.2
Patti, M.E.3
Bruning, J.C.4
Haag, Br.5
Johnson, R.S.6
Kahn, C.R.7
-
20
-
-
0028132214
-
Insulin receptor substrate 1 mediates the stimulatory effect of insulin on GLUT4 translocation in transfected rat adipose cells
-
Quon MJ, Butte AJ, Zarnowski MJ, Sesti G, Cushman SW, Taylor SI (1994) Insulin receptor substrate 1 mediates the stimulatory effect of insulin on GLUT4 translocation in transfected rat adipose cells. J Biol Chem 269:27920-27924
-
(1994)
J Biol Chem
, vol.269
, pp. 27920-27924
-
-
Quon, M.J.1
Butte, A.J.2
Zarnowski, M.J.3
Sesti, G.4
Cushman, S.W.5
Taylor, S.I.6
-
21
-
-
0023736417
-
The insulin receptor and the molecular mechanism of insulin action
-
Kahn CR, White MF (1988) The insulin receptor and the molecular mechanism of insulin action. J Clin Invest 82:1151-1156
-
(1988)
J Clin Invest
, vol.82
, pp. 1151-1156
-
-
Kahn, C.R.1
White, M.F.2
-
22
-
-
0024592297
-
Effects of the tumour promoter okadaic acid on intracellular protein phosphorylation and metabolism
-
Haystead TA, Sim AT, Carling D, Honnor RC, Tsukitani Y, Cohen P, Hardie DG (1989) Effects of the tumour promoter okadaic acid on intracellular protein phosphorylation and metabolism. Nature 337:78-81
-
(1989)
Nature
, vol.337
, pp. 78-81
-
-
Haystead, T.A.1
Sim, A.T.2
Carling, D.3
Honnor, R.C.4
Tsukitani, Y.5
Cohen, P.6
Hardie, D.G.7
-
23
-
-
0025221039
-
Stimulation of glucose transport and glucose transport phosphorylation by okadaic acid in rat adipocytes
-
Lawrence JCJ, Hiken JF, James DE (1990) Stimulation of glucose transport and glucose transport phosphorylation by okadaic acid in rat adipocytes. J Biol Chem 265:19768-19776
-
(1990)
J Biol Chem
, vol.265
, pp. 19768-19776
-
-
Lawrence, J.C.J.1
Hiken, J.F.2
James, D.E.3
-
24
-
-
0027279176
-
Howreceptor tyrosine kinase activate Ras
-
Schlessinger J (1993) Howreceptor tyrosine kinase activate Ras. Trends Biochem Sci 18:273-275
-
(1993)
Trends Biochem Sci
, vol.18
, pp. 273-275
-
-
Schlessinger, J.1
-
26
-
-
0028464349
-
Regulation of the Ras signalling network
-
Maruta H, Burgess AW (1994) Regulation of the Ras signalling network. Bioessays 16:489-496
-
(1994)
Bioessays
, vol.16
, pp. 489-496
-
-
Maruta, H.1
Burgess, A.W.2
-
27
-
-
0028352043
-
Role of IRS-1-GRB-2 complexes in insulin signaling
-
Myers M, Jr, Wang LM, Sun XJ, Zhang Y, Yenush L, Schlessinger J, Pierce JH, White MF (1994) Role of IRS-1-GRB-2 complexes in insulin signaling. Molec Cell Biol 14:3577-3587
-
(1994)
Molec Cell Biol
, vol.14
, pp. 3577-3587
-
-
Myers M., Jr.1
Wang, L.M.2
Sun, X.J.3
Zhang, Y.4
Yenush, L.5
Schlessinger, J.6
Pierce, J.H.7
White, M.F.8
-
28
-
-
0023182603
-
Ras p21 as a potential mediator of insulin action in Xenopus oocytes
-
Korn LJ, Siebel CW, McCormick F, Roth RA (1987) Ras p21 as a potential mediator of insulin action in Xenopus oocytes. Science 236:840-843
-
(1987)
Science
, vol.236
, pp. 840-843
-
-
Korn, L.J.1
Siebel, C.W.2
McCormick, F.3
Roth, R.A.4
-
29
-
-
0023117310
-
Insulin induction of Xenopus laevis oocyte maturation is inhibited by monoclonal antibody against p21 ras proteins
-
Deshpande AK, Kung HF (1987) Insulin induction of Xenopus laevis oocyte maturation is inhibited by monoclonal antibody against p21 ras proteins. Mol Cell Biol 7:1285-1288
-
(1987)
Mol Cell Biol
, vol.7
, pp. 1285-1288
-
-
Deshpande, A.K.1
Kung, H.F.2
-
30
-
-
0027998852
-
Insulin and insulin-like growth factor-1 signal transduction requires p21 (ras)
-
Jhun BH, Meinkoth JL, Leitner JW, Draznin B, Olefsky JM (1994) Insulin and insulin-like growth factor-1 signal transduction requires p21 (ras). J Biol Chem 269:5699-5704
-
(1994)
J Biol Chem
, vol.269
, pp. 5699-5704
-
-
Jhun, B.H.1
Meinkoth, J.L.2
Leitner, J.W.3
Draznin, B.4
Olefsky, J.M.5
-
33
-
-
0028924009
-
A dominant-negative mutant of msosl inhibits insulin-induced ras activation and reveals ras-dependent and ras-independent insulin signaling pathways
-
Sakaue M, Bowtell D, Kasuga M (1995) A dominant-negative mutant of msosl inhibits insulin-induced ras activation and reveals ras-dependent and ras-independent insulin signaling pathways. Molec Cell Biol 15:379-388
-
(1995)
Molec Cell Biol
, vol.15
, pp. 379-388
-
-
Sakaue, M.1
Bowtell, D.2
Kasuga, M.3
-
34
-
-
0026483357
-
Function of ras as a molecular switch in signal transduction
-
Satoh T, Nakafuku M, Yoshito Y (1992) Function of ras as a molecular switch in signal transduction. J Biol Chem 267:24149-24152
-
(1992)
J Biol Chem
, vol.267
, pp. 24149-24152
-
-
Satoh, T.1
Nakafuku, M.2
Yoshito, Y.3
-
35
-
-
0027215518
-
The Ras signaling pathway mimics insulin action on glucose transporter translocation
-
Kozma L, Baltensperger K, Klarlund J, Porras A, Santos E, Czech MP (1993) The Ras signaling pathway mimics insulin action on glucose transporter translocation. Proc Natl Acad Sci USA 90:4460-4464
-
(1993)
Proc Natl Acad Sci USA
, vol.90
, pp. 4460-4464
-
-
Kozma, L.1
Baltensperger, K.2
Klarlund, J.3
Porras, A.4
Santos, E.5
Czech, M.P.6
-
37
-
-
0029120061
-
Roles of 1-phosphatidylinositol 3-kinase and ras in regulating translocation of GLUT4 in transfected rat adipose cells
-
Quon M, Chen H, Ing B, Liu M-L, Zarnowski M, Yonezawa K, Kasuga M, Cushman S, Taylor S (1995) Roles of 1-phosphatidylinositol 3-kinase and ras in regulating translocation of GLUT4 in transfected rat adipose cells. Mol Cell Biol 15:5403-5411
-
(1995)
Mol Cell Biol
, vol.15
, pp. 5403-5411
-
-
Quon, M.1
Chen, H.2
Ing, B.3
Liu, M.-L.4
Zarnowski, M.5
Yonezawa, K.6
Kasuga, M.7
Cushman, S.8
Taylor, S.9
-
38
-
-
0027337519
-
Complexes of Ras.GTP with Raf-1 and mitogen-activated protein kinase kinase
-
Moodie SA, Willumsen BM, Weber MJ, Wolfman A (1993) Complexes of Ras.GTP with Raf-1 and mitogen-activated protein kinase kinase. Science 260:1658-1661
-
(1993)
Science
, vol.260
, pp. 1658-1661
-
-
Moodie, S.A.1
Willumsen, B.M.2
Weber, M.J.3
Wolfman, A.4
-
39
-
-
0027337248
-
Normal and oncogenic p21ras proteins bind to the amino-terminal regulatory domain of c-Raf-1
-
Zhang X-F, Settleman J, Kyriakis K, Takeuch-Suzuki E, Elledge S, Marshall M, Bruder J, Rapp U, Avruch J (1993) Normal and oncogenic p21ras proteins bind to the amino-terminal regulatory domain of c-Raf-1. Nature 364:308-313
-
(1993)
Nature
, vol.364
, pp. 308-313
-
-
Zhang, X.-F.1
Settleman, J.2
Kyriakis, K.3
Takeuch-Suzuki, E.4
Elledge, S.5
Marshall, M.6
Bruder, J.7
Rapp, U.8
Avruch, J.9
-
40
-
-
0027250250
-
Mammalian Ras interacts directly with the serne/threonine kinase Raf
-
Vojtek A, Hollenbeck S, Cooper J (1993) Mammalian Ras interacts directly with the serne/threonine kinase Raf. Cell 74:205-214
-
(1993)
Cell
, vol.74
, pp. 205-214
-
-
Vojtek, A.1
Hollenbeck, S.2
Cooper, J.3
-
41
-
-
0026641090
-
Activation of mitogen-activated protein kinase kinase by v-Raf in NIH 3T3 cells and in vitro
-
Dent P, Haser W, Haystead TA, Vincent LA, Roberts TM, Sturgill TW (1992) Activation of mitogen-activated protein kinase kinase by v-Raf in NIH 3T3 cells and in vitro. Science 257:1404-1407
-
(1992)
Science
, vol.257
, pp. 1404-1407
-
-
Dent, P.1
Haser, W.2
Haystead, T.A.3
Vincent, L.A.4
Roberts, T.M.5
Sturgill, T.W.6
-
42
-
-
0028226008
-
A role for raf-1 in the divergent signaling pathways mediating insulin-stimulated glucose transport
-
Fingar DC, Birnbaum MJ (1994) A role for raf-1 in the divergent signaling pathways mediating insulin-stimulated glucose transport. J Biol Chem 269:10127-10132
-
(1994)
J Biol Chem
, vol.269
, pp. 10127-10132
-
-
Fingar, D.C.1
Birnbaum, M.J.2
-
43
-
-
0028158631
-
rsk signaling pathway in 3T3-L1 adipocytes and its role in insulin-stimulated glucose transport
-
rsk signaling pathway in 3T3-L1 adipocytes and its role in insulin-stimulated glucose transport. Endocrinol 134:728-735
-
(1994)
Endocrinol
, vol.134
, pp. 728-735
-
-
Fingar, D.C.1
Birnbaum, M.J.2
-
44
-
-
0027379099
-
Mitogen-activated protein kinase activation is not sufficient for stimulation of glucose transport of glycogen aynthase in 3T3-L1 Adipocytes
-
Robinson LJ, Razzack ZF, Lawrence JCJ, James DE (1993) Mitogen-activated protein kinase activation is not sufficient for stimulation of glucose transport of glycogen aynthase in 3T3-L1 Adipocytes. J Biol Chem 268:26422-26427
-
(1993)
J Biol Chem
, vol.268
, pp. 26422-26427
-
-
Robinson, L.J.1
Razzack, Z.F.2
Lawrence, J.C.J.3
James, D.E.4
-
45
-
-
0028297696
-
Activation of the Ras/mitogen-activated protein kinase signaling pathway alone is not sufficient to induce glucose uptake in 3T3-L1 adipocytes
-
van den Berghe N, Ouwens DM, Maassen JA, van Mackelenbergh MG, Sips HC, Krans HM (1994) Activation of the Ras/mitogen-activated protein kinase signaling pathway alone is not sufficient to induce glucose uptake in 3T3-L1 adipocytes. Molec Cell Biol 14:2372-2377
-
(1994)
Molec Cell Biol
, vol.14
, pp. 2372-2377
-
-
Van Den Berghe, N.1
Ouwens, D.M.2
Maassen, J.A.3
Van Mackelenbergh, M.G.4
Sips, H.C.5
Krans, H.M.6
-
46
-
-
0027158159
-
The insulin receptor substrate 1 associates with the SH2-containing phosphotyrosine phosphatase Syp.
-
Kuhne MR, Pawson T, Lienhard GE, Feng GS (1993) The insulin receptor substrate 1 associates with the SH2-containing phosphotyrosine phosphatase Syp. J Biol Chem 268:11479-11481
-
(1993)
J Biol Chem
, vol.268
, pp. 11479-11481
-
-
Kuhne, M.R.1
Pawson, T.2
Lienhard, G.E.3
Feng, G.S.4
-
47
-
-
0027432407
-
Activation of the SH2-containing phosphotyrosine phosphatase SH-PTP2 by its binding site, phosphotyrosine 1009, on the human platelet-derived growth factor receptor
-
Lechleider RJ, Sugimoto S, Bennett AM, Kashishian AS, Cooper JA, Shoelson SE, Walsh CT, Neel BG (1993) Activation of the SH2-containing phosphotyrosine phosphatase SH-PTP2 by its binding site, phosphotyrosine 1009, on the human platelet-derived growth factor receptor. J Biol Chem 268:21478-21481
-
(1993)
J Biol Chem
, vol.268
, pp. 21478-21481
-
-
Lechleider, R.J.1
Sugimoto, S.2
Bennett, A.M.3
Kashishian, A.S.4
Cooper, J.A.5
Shoelson, S.E.6
Walsh, C.T.7
Neel, B.G.8
-
48
-
-
0027531637
-
SH2-containing phosphotyrosine phosphatase as a target of protein-tyrosine kinases
-
Feng GS, Hui CC, Pawson T (1993) SH2-containing phosphotyrosine phosphatase as a target of protein-tyrosine kinases. Science 259:1607-1611
-
(1993)
Science
, vol.259
, pp. 1607-1611
-
-
Feng, G.S.1
Hui, C.C.2
Pawson, T.3
-
49
-
-
0027490590
-
Tyrosyl phosphorylation and growth factor receptor association of the human corkscrew homologue, SH-PTP2
-
Lechleider RJ, Freeman Jr RM, Neel BG (1993) Tyrosyl phosphorylation and growth factor receptor association of the human corkscrew homologue, SH-PTP2. J Biol Chem 268:13434-13438
-
(1993)
J Biol Chem
, vol.268
, pp. 13434-13438
-
-
Lechleider, R.J.1
Freeman R.M., Jr.2
Neel, B.G.3
-
50
-
-
0027399168
-
Activation of a phosphotyrosine phosphatase by tyrosine phosphorylation
-
Vogel W, Lammers R, Huang J, Ullrich A (1993) Activation of a phosphotyrosine phosphatase by tyrosine phosphorylation. Science 259:1611-1614
-
(1993)
Science
, vol.259
, pp. 1611-1614
-
-
Vogel, W.1
Lammers, R.2
Huang, J.3
Ullrich, A.4
-
51
-
-
0028179013
-
Protein-tyrosine-phosphatase SHPTP2 couples platelet-derived growth factor receptor beta to Ras
-
Bennett AM, Tang TL, Sugimoto S, Walsh CT, Neel BG (1994) Protein-tyrosine-phosphatase SHPTP2 couples platelet-derived growth factor receptor beta to Ras. Proc Natl Acad Sci USA 91:7335-7339
-
(1994)
Proc Natl Acad Sci USA
, vol.91
, pp. 7335-7339
-
-
Bennett, A.M.1
Tang, T.L.2
Sugimoto, S.3
Walsh, C.T.4
Neel, B.G.5
-
52
-
-
0028245594
-
A molecular description of synaptic vesicle membrane trafficking
-
Bennett MK, Scheller RH (1994) A molecular description of synaptic vesicle membrane trafficking. Annu Rev Biochem 63:63-100
-
(1994)
Annu Rev Biochem
, vol.63
, pp. 63-100
-
-
Bennett, M.K.1
Scheller, R.H.2
-
53
-
-
0028123457
-
A new function for a phosphotyrosine phosphatase: Linking GRB2-Sos to a receptor tyrosine kinase
-
Li W, Nishimura R, Kashishian A, Batzer AG, Kim WJ, Cooper JA, Schlessinger J (1994) A new function for a phosphotyrosine phosphatase: linking GRB2-Sos to a receptor tyrosine kinase. Mol Cell Biol 14:509-517
-
(1994)
Mol Cell Biol
, vol.14
, pp. 509-517
-
-
Li, W.1
Nishimura, R.2
Kashishian, A.3
Batzer, A.G.4
Kim, W.J.5
Cooper, J.A.6
Schlessinger, J.7
-
54
-
-
0027990829
-
Syp (SH-PTP2) is a positive mediator of growth factor-stimulated mitogenic signal transduction
-
Xiao S, Rose DW, Sasaoka T, Maegawa H, Burke Jr TR, Roller PP, Shoelson SE, Olefsky JM (1994) Syp (SH-PTP2) is a positive mediator of growth factor-stimulated mitogenic signal transduction. J Biol Chem 269:21244-21248
-
(1994)
J Biol Chem
, vol.269
, pp. 21244-21248
-
-
Xiao, S.1
Rose, D.W.2
Sasaoka, T.3
Maegawa, H.4
Burke T.R., Jr.5
Roller, P.P.6
Shoelson, S.E.7
Olefsky, J.M.8
-
55
-
-
0028854920
-
Potent stimulation of SH-PTP2 phosphatase activity by simultaneous occupancy of both SH2 domains
-
Pluskey S, Wandless T, Walsh C, Shoelson S (1995) Potent stimulation of SH-PTP2 phosphatase activity by simultaneous occupancy of both SH2 domains. J Biol Chem 270:2879-2900
-
(1995)
J Biol Chem
, vol.270
, pp. 2879-2900
-
-
Pluskey, S.1
Wandless, T.2
Walsh, C.3
Shoelson, S.4
-
56
-
-
0028282967
-
Activation of the SH2-containing protein tyrosine phosphatase, SH-PTP2, by phosphotyrosine-containing peptides derived from insulin receptor substrate-1
-
Sugimoto S, Wandless TJ, Shoelson SE, Neel BG, Walsh CT (1994) Activation of the SH2-containing protein tyrosine phosphatase, SH-PTP2, by phosphotyrosine-containing peptides derived from insulin receptor substrate-1. J Biol Chem 269:13614-13622
-
(1994)
J Biol Chem
, vol.269
, pp. 13614-13622
-
-
Sugimoto, S.1
Wandless, T.J.2
Shoelson, S.E.3
Neel, B.G.4
Walsh, C.T.5
-
57
-
-
0029065980
-
Different signaling roles of SHPTP2 in insulin-induced GLUT1 expression and GLUT4 translocation
-
Hausdorff S, Bennet A, Neel B, Birnbaum M (1995) Different signaling roles of SHPTP2 in insulin-induced GLUT1 expression and GLUT4 translocation. J Biol Chem 270:12965-12968
-
(1995)
J Biol Chem
, vol.270
, pp. 12965-12968
-
-
Hausdorff, S.1
Bennet, A.2
Neel, B.3
Birnbaum, M.4
-
58
-
-
0026069474
-
Oncogenes and signal transduction
-
Cantley LC, Auger KR, Carpenter C, Duckworth B, Graziani A, Kapeller R, Soltoff S (1991) Oncogenes and signal transduction. Cell 64:281-302
-
(1991)
Cell
, vol.64
, pp. 281-302
-
-
Cantley, L.C.1
Auger, K.R.2
Carpenter, C.3
Duckworth, B.4
Graziani, A.5
Kapeller, R.6
Soltoff, S.7
-
59
-
-
0027135003
-
Regulation of phosphatidylinositol 3-kinase by insulin in rat skeletal muscle
-
Chen KS, Friel JC, Ruderman NB (1993) Regulation of phosphatidylinositol 3-kinase by insulin in rat skeletal muscle. Am J Physiol 265:E736-742
-
(1993)
Am J Physiol
, vol.265
-
-
Chen, K.S.1
Friel, J.C.2
Ruderman, N.B.3
-
60
-
-
0026539998
-
Insulin stimulation of phosphatidylinositol 3-kinase activity and association with insulin receptor substrate 1 in liver and muscle of the intact rat
-
Folli F, Saad MJA, Backer JB, Kahn CR (1992) Insulin stimulation of phosphatidylinositol 3-kinase activity and association with insulin receptor substrate 1 in liver and muscle of the intact rat. J Biol Chem 267:22171-22177
-
(1992)
J Biol Chem
, vol.267
, pp. 22171-22177
-
-
Folli, F.1
Saad, M.J.A.2
Backer, J.B.3
Kahn, C.R.4
-
61
-
-
0026640730
-
Phosphatidylinositol-3-kinase in isolated rat adipocytes. Activation by insulin and subcellular distribution
-
Kelly KL, Ruderman NB, Chen KS (1992) Phosphatidylinositol-3-kinase in isolated rat adipocytes. Activation by insulin and subcellular distribution. J Biol Chem 267:3423-3428
-
(1992)
J Biol Chem
, vol.267
, pp. 3423-3428
-
-
Kelly, K.L.1
Ruderman, N.B.2
Chen, K.S.3
-
63
-
-
0028486018
-
Phosphatidylinositol 3-kinase
-
Kapeller R, Cantley L (1994) Phosphatidylinositol 3-kinase. Bioessays 16:565-576
-
(1994)
Bioessays
, vol.16
, pp. 565-576
-
-
Kapeller, R.1
Cantley, L.2
-
64
-
-
0027905021
-
Phosphatidylinositol 3-kinase encoded by yeast VPS34 gene essential for protein sorting
-
Schu PV, Takegawa K, Fry MJ, Stack JH, Waterfield MD, Emr SD (1993) Phosphatidylinositol 3-kinase encoded by yeast VPS34 gene essential for protein sorting. Science 260:88-91
-
(1993)
Science
, vol.260
, pp. 88-91
-
-
Schu, P.V.1
Takegawa, K.2
Fry, M.J.3
Stack, J.H.4
Waterfield, M.D.5
Emr, S.D.6
-
65
-
-
0028124189
-
Essential role of phosphatidylinositol 3-kinase in insulin-induced glucose transport and antilipolysis in rat adipocytes. Studies with a selective inhibitor wortmannin
-
Okada T, Kawano Y, Sabakibara T, Hazeki O, Ui M (1994) Essential role of phosphatidylinositol 3-kinase in insulin-induced glucose transport and antilipolysis in rat adipocytes. Studies with a selective inhibitor wortmannin. J Biol Chem 269:3568-3573
-
(1994)
J Biol Chem
, vol.269
, pp. 3568-3573
-
-
Okada, T.1
Kawano, Y.2
Sabakibara, T.3
Hazeki, O.4
Ui, M.5
-
66
-
-
0028308412
-
Phosphatidylinositol 3-kinase activation is required for insulin stimulation of pp70 S6 kinase, DNA synthesis, and glucose transporter translocation
-
Cheatham B, Vlahos CJ, Cheatham L, Wang L, Blenis J, Kahn CR (1994) Phosphatidylinositol 3-kinase activation is required for insulin stimulation of pp70 S6 kinase, DNA synthesis, and glucose transporter translocation. Mol Cell Biol 14:4902-4911
-
(1994)
Mol Cell Biol
, vol.14
, pp. 4902-4911
-
-
Cheatham, B.1
Vlahos, C.J.2
Cheatham, L.3
Wang, L.4
Blenis, J.5
Kahn, C.R.6
-
67
-
-
0028260280
-
Inhibition of the translocation of GLUT1 and GLUT4 in 3T3-L1 cells by the phosphatidylinositol 3-kinase inhibitor, wortmannin
-
Clarke JF, Young PW, Yonezawa K, Kasuga M, Holman GD (1994) Inhibition of the translocation of GLUT1 and GLUT4 in 3T3-L1 cells by the phosphatidylinositol 3-kinase inhibitor, wortmannin. Biochem J 300:631-635
-
(1994)
Biochem J
, vol.300
, pp. 631-635
-
-
Clarke, J.F.1
Young, P.W.2
Yonezawa, K.3
Kasuga, M.4
Holman, G.D.5
-
68
-
-
0028947991
-
The effects of wortmannin on rat skeletal muscle. Dissociation of signaling pathways for insulin- and con traction-activated hexose transport
-
Yeh JI, Gulve EA, Rameh L, Birnbaum MJ (1995) The effects of wortmannin on rat skeletal muscle. Dissociation of signaling pathways for insulin- and con traction-activated hexose transport. J Biol Chem 270:2107-2111
-
(1995)
J Biol Chem
, vol.270
, pp. 2107-2111
-
-
Yeh, J.I.1
Gulve, E.A.2
Rameh, L.3
Birnbaum, M.J.4
-
69
-
-
0027484001
-
Regulation of phosphatidylinositol 3-kinase activity in liver and muscle of animal models of insulin-resistant and insulin-deficient diabetes mellitus
-
Folli F, Saad MJ, Backer JM, Kahn CR (1993) Regulation of phosphatidylinositol 3-kinase activity in liver and muscle of animal models of insulin-resistant and insulin-deficient diabetes mellitus. J Clin Invest 92:1787-1794
-
(1993)
J Clin Invest
, vol.92
, pp. 1787-1794
-
-
Folli, F.1
Saad, M.J.2
Backer, J.M.3
Kahn, C.R.4
-
70
-
-
0027489828
-
Modulation of insulin receptor, insulin receptor substrate-1, and phosphatidylinositol 3-kinase in liver and muscle of dexamethasone-treated rats
-
Saad MJA, Folli F, Kahn JA, Kahn CR (1993) Modulation of insulin receptor, insulin receptor substrate-1, and phosphatidylinositol 3-kinase in liver and muscle of dexamethasone-treated rats. J Clin Invest 92:2065-2072
-
(1993)
J Clin Invest
, vol.92
, pp. 2065-2072
-
-
Saad, M.J.A.1
Folli, F.2
Kahn, J.A.3
Kahn, C.R.4
-
71
-
-
0028813922
-
Activation of mitogen-activated protein kinase and phosphatidylinositol 3′-kinase is not sufficient for the hormonal stimulation of glucose uptake, lipogenesis, or glycogen synthesis in 3T3-L1 adipocytes
-
Wiese RJ, Mastick CC, Lazar DF, Saltiel AR (1995) Activation of mitogen-activated protein kinase and phosphatidylinositol 3′-kinase is not sufficient for the hormonal stimulation of glucose uptake, lipogenesis, or glycogen synthesis in 3T3-L1 adipocytes. J Biol Chem 270:3442-3446
-
(1995)
J Biol Chem
, vol.270
, pp. 3442-3446
-
-
Wiese, R.J.1
Mastick, C.C.2
Lazar, D.F.3
Saltiel, A.R.4
-
72
-
-
0028178928
-
PDGF- and insulin-dependent pp70S6k activation mediated by phosphatidylinositol-3-OH kinase
-
Chung J, Grammer TC, Lemon KP, Kazlauskas A, Blenis J (1994) PDGF- and insulin-dependent pp70S6k activation mediated by phosphatidylinositol-3-OH kinase. Nature 370:71-75
-
(1994)
Nature
, vol.370
, pp. 71-75
-
-
Chung, J.1
Grammer, T.C.2
Lemon, K.P.3
Kazlauskas, A.4
Blenis, J.5
-
73
-
-
0026659046
-
Rapamycin-FKBP specifically blocks growth-dependent activation of and signaling by the 70 kd S6 protein kinases
-
Chung J, Kuo CJ, Crabtree GR, Blenis J (1992) Rapamycin-FKBP specifically blocks growth-dependent activation of and signaling by the 70 kd S6 protein kinases. Cell 69:1227-1236
-
(1992)
Cell
, vol.69
, pp. 1227-1236
-
-
Chung, J.1
Kuo, C.J.2
Crabtree, G.R.3
Blenis, J.4
-
74
-
-
0026721092
-
Rapamycin selectively inhibits interleukin-2 activation of p70 S6 kinase
-
Kuo CJ, Chung J, Fiorentino DF, Flanagan WM, Blenis J, Crabtree GR (1992) Rapamycin selectively inhibits interleukin-2 activation of p70 S6 kinase. Nature 358:70-73
-
(1992)
Nature
, vol.358
, pp. 70-73
-
-
Kuo, C.J.1
Chung, J.2
Fiorentino, D.F.3
Flanagan, W.M.4
Blenis, J.5
Crabtree, G.R.6
-
75
-
-
0027536041
-
Dissociation of pp70 ribosomal protein S6 kinase from insulin-stimulated glucose transport in 3T3-L1 adipocytes
-
Fingar DC, Hausdorff SF, Blenis J, Birnbaum MJ (1993) Dissociation of pp70 ribosomal protein S6 kinase from insulin-stimulated glucose transport in 3T3-L1 adipocytes. J Biol Chem 268:3005-3008
-
(1993)
J Biol Chem
, vol.268
, pp. 3005-3008
-
-
Fingar, D.C.1
Hausdorff, S.F.2
Blenis, J.3
Birnbaum, M.J.4
-
76
-
-
0029079275
-
The protein kinase encoded by the Akt proto-oncogene is a target of the PDGF-activated phosphatidylinositol 3-kinase
-
Franke TF, Yang SI, Chan TO, Datta K, Kazalauskas A, Morrison DK, Kaplan DR, Tsichlis PN (1995) The protein kinase encoded by the Akt proto-oncogene is a target of the PDGF-activated phosphatidylinositol 3-kinase. Cell 81:727-736
-
(1995)
Cell
, vol.81
, pp. 727-736
-
-
Franke, T.F.1
Yang, S.I.2
Chan, T.O.3
Datta, K.4
Kazalauskas, A.5
Morrison, D.K.6
Kaplan, D.R.7
Tsichlis, P.N.8
-
77
-
-
0029160069
-
Protein kinase N (c-Akt) in phosphatidylinositol-3-OH kinase signal transduction
-
Burgering M, Coffer P (1995) Protein kinase N (c-Akt) in phosphatidylinositol-3-OH kinase signal transduction. Nature 376:599-602
-
(1995)
Nature
, vol.376
, pp. 599-602
-
-
Burgering, M.1
Coffer, P.2
-
78
-
-
0029143388
-
Insulin stimulates the kinase activity of RAC-PK, a pleckstrin homology domain containing ser/thr kinase
-
Kohn A, Kovacina K, Roth R (1995) Insulin stimulates the kinase activity of RAC-PK, a pleckstrin homology domain containing ser/thr kinase. EMBO J 14:4288-4295
-
(1995)
EMBO J
, vol.14
, pp. 4288-4295
-
-
Kohn, A.1
Kovacina, K.2
Roth, R.3
|