17β-estradiol inhibits vascular smooth muscle cell proliferation and c-fos expression: Role of nitric oxide

Acta Physiologica Sinica

Volumn 54, Issue 1, 2002, Pages 17-22

  Yang, Dan ^a   Tan, Zhi ^a   Liu, Pei Qing ^a   Pan, Jing Yun ^a   Wang, Ting Huai ^a  

^a SUN YAT SEN UNIVERSITY   (China)

Author keywords

C fos; Estrogen; Nitric oxide; Nitric oxide synthase; Vascular smooth muscle cell

Indexed keywords

ESTRADIOL; MESSENGER RNA; NITRIC OXIDE; PROTEIN C FOS;

ANIMAL; ARTICLE; BIOSYNTHESIS; CELL CULTURE; CELL DIVISION; CYTOLOGY; DRUG EFFECT; FEMALE; METABOLISM; PHYSIOLOGY; RAT; SPRAGUE DAWLEY RAT; VASCULAR SMOOTH MUSCLE;

ANIMALS; CELL DIVISION; CELLS, CULTURED; ESTRADIOL; FEMALE; MUSCLE, SMOOTH, VASCULAR; NITRIC OXIDE; PROTO-ONCOGENE PROTEINS C-FOS; RATS; RATS, SPRAGUE-DAWLEY; RNA, MESSENGER;

EID: 0040079932     PISSN: 03710874     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (17)

1. Hayashi T, Yamada K. Esaki T, Kuzuya M, Satake S, Ishikawa T, Hidaka H, Iguchi A. Estrogen increases endothelial nitric oxide by a receptor-mediated system. Biochem Biophys Res Commun , 1995, 214(3): 847-855.
2. Morey AK, Pedram A, Razandi M et al. Morey AK, Pedram A, Razandi M, Prins BA, Hu RM, Biesiada E, Levin ER. Estrogen and progesterone inhibit vascular smooth muscle proliferation. Endocrinology, 1997, 138 (8): 3330-3339.
3. Binko J, Majewski H. 17 beta-Estradiol reduces vasoconstriction in endothelium-denuded rat aortas through inducible NOS. Am J Physiol, 1998, 274 (3 Pt 2): H853-H859.
4. Hirata Y, Takagi Y, Takata S. CGRP receptor in cultured vascular smooth muscle and endothelial cells. Biochem Biophys Res Commun, 1988, 151:1113-1121.
5. Yang K. Mu XS, Xue JJ. Whitson J, Salminen A, dixon CE, Liu PK, Hayes RL. Increased expression of c-fos mRNA and AP-1 transcription factors after cortical impact injury in rat. Brain Res, 1994, 664: 141-147. .
6. Fort P, Marty L, Piechaczyk M. Various rat adult tissues express only one major mRNA species from the glyceraldehydes-3-phosphate-dehydrogenate multigenic family. Nucleic Acids Res , 1985, 13: 1431-1442.
7. Hayashi T, Jayachandran M, Sumi D, Thakur NK, Esaki T, Muto E, Kano H, Asai Y, Iguchi A. Physiological concentration of 17 beta-estradiol retards the progression of severe atherosclerosis induced by a high-cholesterol diet plus balloon catheter injury: role of NO. Arterioscler Thromb Vasc Biol, 2000 20(6): 1613-1621.
8. Wang TH, Yang D, Liu PQ, Gong SZ, Lu W, Pan JY, 17β-estradiol induced nitric oxide release in vascular endothelial cells. Acta Physiol Sin, 2000. 52 (6):479-482 (Chinese, English abstract).
9. Nuedling S, Kahlert S, Loebbert K, Doevendans PA, Meyer R, Vetter H, Grohe C. 17 Beta-estradiol stimulates expression of endothelial and inducible NO synthase in rat myocardium in-vitro and in-vivo. Cardiovasc Res, 1999, 43(3): 666-674
10. Buttery LDK, Springall DR, Chester AH, Evans TJ, Standfield EN, Parums DV, Yacoub MH, Polak JM. Inducible nitric oxide synthase is present within human atherosclerotic lesion and promotes the formation and activity of peroxinitrite. Lab Invest, 1996, 75:177-185.
11. Zancan V, Santagati S, Bolego C, Vegeto E, Maggi A, Puglisi L. 17β-estradiol decreases nitric oxide synthase II synthesis in vascular smooth muscle cells. Endocrinology, 1999, 140(5): 2004-2009.
12. Kauser K, Sonnenberg D, Diel P, Rubanyi GM. Effect of 17β-estradiol on cytokine-induced nitric oxide production in rat isolated aorta. Br J Pharmacol, 1998, 123: 1089-1096.
13. Ikeda U, Yamamoto K, Maeda Y, Shimpo M, Kanbe T, Shimada K. Endothelin-1 inhibits nitric oxide synthesis in vascular smooth muscle cells. Hypertension, 1997, 29(1 Pt 1): 65-69.
14. Dulak J, Polus M, Guevara I, Polus A, Hartwich J, Dembinska-Kiec A. Regulation of inducible nitric oxide synthase (iNOS) and GTP cyclohydrolase (GPT-CH 1) gene expression by ox-LDL in rat vascular smooth muscle cells. J Physiol Pharmacol, 1997, 48(4): 689-697.
15. Rikitake Y, Hirata K, Kawashima S. Akita H, Yokoyama M. Inhibitory effect of inducible type nitric oxide synthase on oxidative modification of low density lipoprotein by vascular smooth muscle cells. Atherosclerosis, 1998, 136(1): 51-57.
16. Kibbe MR, Li J, Nie S, Watkins SC, Lizonova A, Kovesdi I, Simmons RL, Billiar TR, Tzeng E. Inducible nitric oxide synthase (iNOS) expression upregulates p21 and inhibits vascular smooth muscle cell proliferation through p42/44 mitogen activated protein kinase activation and independent of p53 and cyclic guanosine monophosphate. J Vasc Surg, 2000, 31(6): 1214-1228.
17. Hodges YK, Tung L, Yan XD, Graham JD, Horwitz KB, Horwitz LD. Estrogen receptors α and β: prevalence of estrogen receptor β mRNA in human vascular smooth muscle and transcriptional effects. Circulation, 2000, 101(15): 1792-1798.