Application of x-ray photoelectron spectroscopy in determining the structure of solid-phase bound substrates

Journal of Combinatorial Chemistry

Volumn 4, Issue 4, 2002, Pages 255-257

  Whitehead, David M ^a   Jackson, Toby ^a   McKeown, Stephen C ^b   Wilson, Karen ^a   Routledge, Anne ^a  

^a UNIVERSITY OF YORK   (United Kingdom)

^b GLAXOSMITHKLINE   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ARTICLE;

EID: 0040077867     PISSN: 15204766     EISSN: None     Source Type: Journal    
DOI: 10.1021/cc020002a     Document Type: Article

References (15)

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11. -1, as determined by elemental analysis.
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13. Procedure for the cleavage of methyl-N-methylindole 3-acetate 5 from resin 4. Resin 4 (0.05 g) was swollen in THF/MeOH (4:1), and excess NaOMe was added. The mixture was agitated for 18 h, the resin was removed by filtration, and the solution was made up to 10 mL. Indole was added (as an internal standard), and an aliquot of the solution was removed and analyzed by HPLC (diode array detection). The yield is based on the loading of resin 1.
14. 3SnH (40:1), and the solution was degassed with nitrogen for 10 min. The solution was photolyzed at 350 nm using a Rayonet photochemical reactor for 30 min. The resin was removed by filtration, and the solution was made up to 10 mL. Indole was added, and an aliquot of the solution was removed and analyzed by HPLC (diode array detection). The yield is based on the loading of resin 1.
15. Wu, S.; Kang, E. T.; Neoh, K. G.; Han, H. S.; Tan, K. L. Macromolecules 1999, 32, 186-193.