Stoichiometry and heterogeneity of the pro-region chain in tetrameric human cathepsin C

Biochimica et Biophysica Acta - Protein Structure and Molecular Enzymology

Volumn 1382, Issue 1, 1998, Pages 143-150

  Cigić, Blaž ^a   Križaj, Igor ^a   Kralj, Bogdan ^a   Turk, Vito ^a   Pain, Roger H ^a  

^a JO EF STEFAN INSTITUTE   (Slovenia)

Author keywords

Cathepsin C; Chain stoichiometry; Dipeptidyl aminopeptidase I; Disulphide bonding; Glycosylation; Propeptide

Indexed keywords

CYSTEINE PROTEINASE; DIPEPTIDYL PEPTIDASE I; DISULFIDE; UNCLASSIFIED DRUG;

AMINO TERMINAL SEQUENCE; ARTICLE; CARBOXY TERMINAL SEQUENCE; DISULFIDE BOND; ENZYME ACTIVITY; ENZYME ANALYSIS; ENZYME GLYCOSYLATION; ENZYME SUBUNIT; HUMAN; MASS SPECTROMETRY; PRIORITY JOURNAL; STOICHIOMETRY;

ALKYLATION; AMINO ACID SEQUENCE; CHROMATOGRAPHY, GEL; CHROMATOGRAPHY, ION EXCHANGE; DIPEPTIDYL PEPTIDASE I; DIPEPTIDYL PEPTIDASES; ENZYME PRECURSORS; HUMANS; KIDNEY; MACROMOLECULAR SUBSTANCES; MOLECULAR SEQUENCE DATA; OXIDATION-REDUCTION; PEPTIDE FRAGMENTS; PROTEIN DENATURATION;

EID: 0040043343     PISSN: 01674838     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0167-4838(97)00173-8     Document Type: Article

References (16)

1. Rawlings N.D., Barrett A.J. Evolutionary families of peptidases. Biochem. J. 290:1993;205-218.
2. H. Kirschke, A.J. Barrett, N.D. Rawlings, Lysosomal cysteine proteinases, in: P. Sheterline (Ed.), Protein Profile, vol. 2, Academic Press, London, 1995, pp. 1587-1643.
3. B. Turk, I. Dolenc, V. Turk, Dipeptidyl peptidase I, in: A.J. Barrett, N.D. Rawlings, J.F. Woessner (Eds.), Handbook of Proteolytic Enzymes, Academic Press, London, 1997, in press.
4. Ishidoh K., Muno D., Sato N., Kominami E. Molecular cloning of cDNA for rat cathepsin C. J. Biol. Chem. 266:1991;16312-16317.
5. Pariš A., Štrukelj B., Pungerčar J., Renko M., Dolenc I., Turk V. Molecular cloning and sequence analysis of human preprocathepsin C. FEBS Lett. 369:1995;326-330.
6. Muno D., Ishidoh K., Ueno T., Kominami E. Processing and transport of the precursor of cathepsin C during its transfer into lysosomes. Arch. Biochem. Biophys. 306:1993;103-110.
7. Gutman H.R., Fruton J.S. On the proteolytic enzymes of animal tissues VII. An intracellular enzyme related to chymotrypsin. J. Biol. Chem. 174:1948;851-858.
8. Dolenc I., Turk B., Pungerčič G., Ritonja A., Turk V. Oligomeric structure and substrate-induced inhibition of cathepsin C. J. Biol. Chem. 270:1995;21626-21631.
9. McGuire M.J., Lipsky P.E., Thiele D.L. Purification and characterisation of dipeptidyl peptidase I from human spleen. Arch. Biochem. Biophys. 295:1992;280-288.
10. Metrione R.M., Okuda Y., Fairclough G.F. Jr. Subunit structure of dipeptidyl transferase. Biochemistry. 9:1970;2427-2432.
11. Metrione R.M., Neves A.G., Fruton J.S. Purification of dipeptidyl transferase (cathepsin C). Biochemistry. 5:1966;1597-1604.
12. De la Haba G., Cammarata P.S., Timasheff S.N. The partial purification and some physical properties of cathepsin C from beef spleen. J. Biol. Chem. 234:1959;316-319.
13. McDonald J.K., Zeitman B.B., Reilly T.J., Ellis S. New observations on the substrate specificity of cathepsin C. J. Biol. Chem. 244:1969;2693-2709.
14. Nikawa T., Towatari T., Katunuma N. Purification and characterisation of cathepsin J from rat liver. Eur. J. Biochem. 204:1992;381-393.
15. Lynn K.R., Labow R.S. A comparison of four sulphydryl cathepsins (B, C, H and L) from porcine spleen. Can. J. Biochem. Cell Biol. 62:1984;1301-1308.
16. Dolenc I., Turk B., Kos J., Turk V. Interaction of human cathepsin C with chicken cystatin. FEBS Lett. 392:1996;277-280.