Synthesis of a water-soluble chiral N-acylcalix(4)arene amino acid derivative

Tetrahedron Letters

Volumn 37, Issue 33, 1996, Pages 5841-5844

  Sánchez Peña, Montserrat ^c   Zhang, Yuling ^c   Thibodeaux, Stefan ^c   McLaughlin, Mark L ^c   Muñoz De La Peña, Arsenio ^b   Warner, Isiah M ^a  

^a LOUISIANA STATE UNIVERSITY   (United States)

^b UNIVERSITY OF EXTREMADURA   (Spain)

^c NONE

Author keywords

[No Author keywords available]

Indexed keywords

AMINO ACID DERIVATIVE; CALIXARENE; MACROCYCLIC COMPOUND;

ARTICLE; CAPILLARY ELECTROPHORESIS; CHIRALITY; CONFORMATION; DERIVATIZATION; ENANTIOMER; PROTON NUCLEAR MAGNETIC RESONANCE; SOLUBILITY; SYNTHESIS;

EID: 0039933232     PISSN: 00404039     EISSN: None     Source Type: Journal    
DOI: 10.1016/0040-4039(96)01240-3     Document Type: Article

References (18)

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13. 25 (c=1 in methanol) -18.93. Hydrolysis of the ester: Hydrolysis of the ester (6) to the acid (7) was achieved by use of TFA and dichloromethane at room temperature. The four carboxylic groups can be converted to the salt form with little difficulty, providing water-soluble calixarene.
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