Transforming growth factor peptide antagonists and their conversion to partial agonists

Journal of Biological Chemistry

Volumn 272, Issue 43, 1997, Pages 27155-97159

  Huang, Shuan Shian ^a   Liu, Qianjin ^a   Johnson, Frank E ^a   Konish, Yasuo ^a   Huang, Jung San ^a  

^a SAINT LOUIS UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALANINE; ARGININE; ASPARTIC ACID; DNA; PENTAPEPTIDE; RECEPTOR BLOCKING AGENT; TRANSFORMING GROWTH FACTOR BETA RECEPTOR; TRANSFORMING GROWTH FACTOR BETA1; TRANSFORMING GROWTH FACTOR BETA2; TRANSFORMING GROWTH FACTOR BETA3; TRYPTOPHAN;

AGONIST; AMINO ACID SEQUENCE; ANIMAL CELL; ARTICLE; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG RECEPTOR BINDING; DRUG STRUCTURE; GROWTH INHIBITION; LUNG ALVEOLUS EPITHELIUM; MINK; NONHUMAN; PRIORITY JOURNAL;

ANIMALS; CELL DIVISION; CELL LINE; DNA; EPITHELIUM; HUMANS; KINETICS; LUNG; MINK; MUTAGENESIS, SITE-DIRECTED; PEPTIDE FRAGMENTS; PLASMINOGEN ACTIVATOR INHIBITOR 1; RECEPTORS, TRANSFORMING GROWTH FACTOR BETA; TRANSFORMING GROWTH FACTOR BETA; VARIATION (GENETICS);

ANIMALIA; MUSTELA VISON;

EID: 0039797251     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.272.43.27155     Document Type: Article

References (27)

1. Massagué, J. (1990) Annu. Rev. Cell Biol. 6, 597-641
2. Roberts, A. B., and Sporn, M. B. (1990) in Handbook of Experimental Pharmacology: Peptide Growth Factors and Their Receptors (Sporn, M. B., and Roberts, A. B., eds) Vol. 95, Part 1, pp. 419-472, Springer-Verlag, New York
3. Wright, J. A., Turley, E. A., and Greenberg, A. H. (1993) Crit. Rev. Oncog. 4, 473-492
4. Border, W. A., and Noble, N. A. (1995) Nat. Med. 1, 1000-1001
5. Border, W. A., and Noble, N. A. (1995) J. Clin. Invest. 96, 655-656
6. Shenkar, R., Coulson, W. F., and Abraham, E. (1994) Am. J. Respir. Cell Mol. Biol. 11, 351-357
7. Shah, M., Foreman, D. M., and Ferguson, M. W. J. (1995) J. Cell Sci. 108, 985-1002
8. Wolf, Y. G., Rasmussen, L. M., and Ruoslahti, E. (1994) J. Clin. Invest. 93, 1172-1178
9. O'Grady, P., Liu, Q., Huang, S. S., and Huang, J. S. (1992) J. Biol. Chem. 267, 21033-21037
10. Liu, Q., Huang, S. S., and Huang, J. S. (1994) J. Biol. Chem. 269, 9221-9226
11. Liu, Q., Huang, S. S., and Huang, J. S. (1997) J. Biol. Chem. 272, 18891-18895
12. O'Grady, P., Kuo, M.-D., Baldassare, J. J., Huang, S. S., and Huang, J. S. (1991) J. Biol. Chem. 266, 8583-8589
13. O'Grady, P., Huang, S. S., and Huang, J. S. (1991) Biochem. Biophys. Res. Commun. 179, 378-385
14. Engström, U., Engström, A., Ernlund, A., Westermark, B., and Heldin, C.-H. (1992) J. Biol. Chem. 267, 16581-16587
15. Derynck, R., Jarrett, J. A., Chen, E. Y., Eaton, D. H., Bell, J. R., Assoian, R. K., Roberts, A. B., Sporn, M. B., and Goeddel, D. V. (1985) Nature 316, 701-705
16. Boyd, F. T., and Massagué, J. (1989) J. Biol. Chem. 264, 2272-2278
17. Cheifetz, S., Hernandez, H., Laiho, M., ten Dijke, P., Iwata, K. K., and Massagué, J. (1990) J. Biol. Chem. 265, 20533-20538
18. Laiho, M., Weis, F. M. B., and Massagué, J. (1990) J. Biol. Chem. 265, 18518-18524
19. Madison L., Webb, N. R., Rose, T. M., Marquardt, H., Ikeda, T., Twardzik, D., Seyedin, S., and Purchio, A. F. (1988) DNA Cell Biol. 7, 18
20. Derynck, R., Lindquist, P. B., Lee, A., Wen, D., Tamm, J., Gracar, J. L., Rhee, L., Mason, A. J., Miller, D. A., Coffey, R. J., Moses, H. L., and Chen, E. Y. (1988) EMBO J. 7, 3737-3743
21. Schlunegger, M. P., and Gnitter, M. G. (1992) Nature 353, 430-434
22. Schlunegger, M. P., and Grutter, M. G. (1993) J. Mol. Biol. 231, 445-458
23. Hinck, A. P., Archer, S. J., Qian, S. W., Roberts, A. B., Sporn, M. B., Weatherbee, J. A., Tsang, M. L.-S., Lucas, R., Zhang, B.-L., Wenker, J., and Torchia, D. A. (1996) Biochemistry 35, 8517-8534
24. Amatayakul-Chantler, S., Qian, S. W., Gakenheimer, K., Böttinger, E. P., Roberts, A. B., and Sporn, M. B. (1994) J. Biol. Chem. 269, 27687-27691
25. Wrana, J. L., Attisano, L., Wieser, R., Ventura, F., and Massagué, J. (1994) Nature 370, 341-347
26. Qian, S. W., Burmester, J. K., Tsang, M. L.-S., Weatherbee, J. A., Hinck, A. P., Ohlsen, D. J., Sporn, M. B., and Roberts, A. B. (1996) J. Biol. Chem. 271, 30656-30662
27. Leal, S. M., Liu, Q., Huang, S. S., and Huang, J. S. (1997) J. Biol. Chem. 272, 20572-20576