Transcriptional activator TGV mediates dexamethasone-inducible and tetracycline-inactivatable gene expression

Plant Journal

Volumn 19, Issue 1, 1999, Pages 87-95

  Böhner, Steffen ^a   Lenk, Ingo ^a   Rieping, Mechthild ^a,b   Herold, Michael ^a   Gatz, Christiane ^a  

^a UNIVERSITY OF GÖTTINGEN   (Germany)

^b BIELEFELD UNIVERSITY   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

BETA GLUCURONIDASE; CAULIFLOWER MOSAIC VIRUS; DEXAMETHASONE; GENE ACTIVATION; GENE INDUCTION; GLUCOCORTICOID RECEPTOR; HERPES SIMPLEX; HORMONE RECEPTOR; PROMOTER REGION; PROTEIN DNA BINDING; STABLE TRANSFECTION; TATA BOX; TETRACYCLINE; TOBACCO; TRANSCRIPTION REGULATION; TRANSGENIC PLANT; VIRION;

EID: 0039776006     PISSN: 09607412     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1365-313X.1999.00503.x     Document Type: Article

References (41)

1. Aoyama, T. and Chua, N.H. (1997) A glucocorticoid-mediated transcriptional induction system in transgenic plants. Plant J. 11, 605-612.
2. Aoyama, T., Dong, C.-H., Wu, Y., Carabelli, M. and Sessa, G. (1995) Ectopic expression of the Arabidopsis transcriptional activator Athb-1 alters leaf cell fate in tobacco. Plant Cell, 7, 1773-1785.
3. Becker, D. (1990) Binary vectors which allow the exchange of plant selectable markers and reporter genes. Nucl. Acids Res. 18, 203.
4. Bevan, M. (1984) Binary Agrobacterium vectors for plant transformation. Nucl. Acids Res. 12, 8711-8721.
5. Caddick, M.X., Greenland, A.J., Jepson, I., Krause, K.P., Qu, N., Riddell, K.V., Salter, M.G., Schuch, W., Sonnewald, U. and Tomsett, A.B. (1998) An. ethanol inducible gene switch for plants used to manipulate carbon metabolism. Nat. Biotechnol. 16, 177-180.
6. Corlett, J.E., Myatt, S.C. and Thompson, A.J. (1996) Toxicity symptoms caused by high expression of Tet repressor in tomato (Lycopersicon esculentum Mill. L.) are alleviated by tetracycline. Plant Cell Environ. 19, 447-454.
7. Deblaere, R., Bytebier, B., De Greve, H., Debroeck, F., Schell, J., van Montagu, M. and Leemans, J. (1985) Efficient octopine Ti plasmid derived vectors for Agrobacterium-mediated gene transfer to plants. Nucl. Acids Res. 13, 4777-4788.
8. Faiss, M., Strnad, M., Redig, P., Dolezal, K., Hanus, J., Van Onckelen, H. and Schmülling, T. (1996) Chemically induced expression of the rolC-encoded β-glucosidase in transgenic tobacco plants and analysis of cytokinin metabolism: rolC does not hydrolyze endogenous cytokinin glucosides in plants. Plant J. 10, 33-46.
9. Faiss, M., Zalubilova, J., Strnad, M. and Schmülling, T. (1997) Conditional transgenic expression of the ipt gene indicates a function for cytokinins in paracrine signaling in whole tobacco plants. Plant J. 12, 401-415.
10. Gatz, C. (1997) Chemical control of gene expression. Annu. Rev. Plant Physiol. Plant Mol. Biol. 48, 89-108.
11. Gatz, C., Frohberg, C. and Wendenburg, R. (1992) Stringent repression and homogeneous de-repression by tetracycline of a modified CaMV 35S promoter in intact transgenic tobacco plants. Plant J. 2, 397-404.
12. Gatz, C., Kaiser, A. and Wendenburg, R. (1991) Regulation of a modified CaMV 35S promoter by the Tn70-encoded Tet repressor in transgenic tobacco. Mol. Gen. Genet. 227, 229-237.
13. Gatz, C. and Quail, P.H. (1988) Tn10-encoded Tet repressor can regulate an operator-containing plant promoter. Proc. Natl Acad. Sci. USA, 85, 1394-1397.
14. Gossen, M., Bonin, A.L. and Bujard, H. (1993) Control of gene activity in higher eukaryotic cells by prokaryotic regulatory elements. Trends Biochem. Sci. 18, 471-475.
15. Gossen, M. and Bujard, H. (1992) Tight control of gene expression in mammalian cells by tetracycline-responsive promoters. Proc. Natl Acad. Sci. USA, 89, 5547-5551.
16. Gossen, M. and Bujard, H. (1993) Anhydrotetracycline, a novel effector for tetracycline controlled gene expession systems in eukaryotic cells. Nucl. Acids. Res. 21, 4411-4412.
17. Hillen, W. and Berens, C. (1994) Mechanisms underlying expression of Tn10 encoded tetracycline resistance. Annu. Rev. Microbiol. 48, 345-369.
18. Ingelbrecht, I., van Houdt, H., van Montagu, M. and Depicker, A. (1994) Posttranscriptional silencing of reporter transgenes in tobacco correlates with DNA methylation. Proc. Natl Acad. Sci. USA, 91, 10502-10506.
19. Jefferson, R.A. (1987) Assaying chimeric genes in plants: The GUS gene fusion system. Plant Mol. Biol. Report, 5, 387-405.
20. Jones, A.M., Im, K.H., Savka, M.A., Wu, M.J., DeWitt, N.G., Shillito, R. and Binns, A.N. (1998) Auxin-dependent cell expansion mediated by overexpressed auxin-binding protein 1. Science, 282, 1114-1117.
21. Katagiri, F., Lam, E. and Chua, N.H. (1989) Two tobacco DNA-binding proteins with homology to the nuclear factor CREB. Nature, 340, 727-730.
22. Krause, G.H. and Weis, E. (1991) Chlorophyll fluorescence and photosynthesis. The basics. Ann. Rev. Plant Phys. Plant Mol. Biol. 42, 313-349.
23. Kumar, A., Taylor, M.A., Arif, S.A.M. and Davies, H.V. (1996) Potato plants expression antisense and sense S-adenosylmethionine decarboxylase (SAMDC) transgenes show altered levels of polyamines and ethylene: antisense plants display abnormal phenotypes. Plant J. 9, 147-158.
24. Laemmli, U.K. (1970) Cleavage of structural proteins during the assembly of the head of the bacteriophage T4. Nature, 227, 680-685.
25. Lloyd, A.M., Schena, M., Walbot, V. and Davis, R.W. (1994) Epidermal cell fate determination in Arabidopsis: patterns defined by a steroid-inducible regulator. Science, 266, 436-439.
26. Masgrau, C., Altabella, T., Farra's, R., Flores, D., Thompson, A.J., Besford, R.T. and Tiburcio, A.F. (1997) Inducible overexpression of oat arginine decarboxylase in transgenic tobacco plants. Plant J. 11, 465-473.
27. Mett, V.L., Lochhead, L.P. and Reynolds, P.M. (1993) Copper-controllable gene expression system for whole plants. Proc. Natl Acad. Sci. USA, 90, 4567-4571.
28. Picard, D. (1994) Regulation of protein function through expression of chimaeric proteins. Curr. Top. Biotech. 5, 511-515.
29. Picard, D., Kursheed, B., Garabedian, M.J., Fortin, M.G., Lindquist, S. and Yamamoto, K.R. (1990) Reduced levels of hsp90 compromise steroid receptor action in vivo. Nature 348, 166-168.
30. Randall, P.J. and Bourma, D. (1973) Zinc deficiency, carbonic anhydrase, and photosynthesis in leaves of spinach. Plant. Physiol. 52, 229-239.
31. Rieping, M., Fritz, M., Prat, S. and Gatz, C. (1994) A. dominant negative mutant of PG13 suppresses transcription from a cauliflower mosaic virus 35S truncated promoter in transgenic tobacco plants. Plant Cell, 6, 1087-1098.
32. Röder, F.T., Schmülling, T. and Gatz, C. (1994) Efficiency of the tetracycline-dependent gene expression system: complete suppression and efficient induction of the rolB phenotype in transgenic plants. Mol. Gen. Gen. 243, 32-38.
33. Rosahl, S., Schmidt, R., Schell, J. and Willmitzer, L. (1987) Expression of a tuber-specific storage protein in transgenic tobacco plants: demonstration of an esterase activity. EMBO J. 6, 1155-1159.
34. Sambrook, J., Fritsch, E.F. and Maniatis, T. (1989) Molecular Cloning. A Laboratory Manual, 2nd edn. Cold Spring Harbor: Cold Spring Harbor Laboratory Press.
35. Shockett, P.E. and Schatz, D.G. (1996) Diverse strategies for tetracycline-regulated inducible gene expression. Proc. Natl Acad. Sci. USA 93, 5173-5176.
36. Simon, R., Igeno, M.I. and Coupland, G. (1996) Activation of floral meristem identity genes in Arabidopsis. Nature, 384, 59-62.
37. Triezenberg, S.J., Kingsbury, R.C. and McKnight, S.L. (1988) Functional dissection of VP16, the trans-activator of herpes simplex virus immediate early gene expression. Genes Devel. 2, 718-729.
38. Van der Krol, A. and Chua, N.H. (1991) The basic domain of plant B-ZIP proteins facilitates import of a reporter protein into plant nuclei. Plant Cell, 3, 667-675.
39. Van der Zaal, B.J., Droog, F.N., Pieterse, F.J. and Hooykaas, P.J. (1996) Auxin-sensitive element from promotors of tobacco GST genes and a consensus as-1-like element differ only in relative strength. Plant Physiol. 110, 79-88.
40. Vancanneyt, G., Schmidt, R., O'Connor-Sanchez, A., Willmitzer, L. and Rocha-Sosa, M. (1990) Construction of an intron-containing marker gene: Splicing of the intron in transgenic plants and its use in monitoring early events in Agrobacterium-mediated plant transformation. Mol. Gen. Genet. 220, 245-250.
41. Weinmann, P., Gossen, M., Hillen, W., Bujard, H. and Gatz, C. (1994) A. chimeric transactivator allows tetracycline-responsive gene expression in whole plants. Plant J. 5, 559-569.