Plant polyketide synthases leading to stilbenoids have a domain catalyzing malonyl-CoA:CO2 exchange, malonyl-CoA decarboxylation, and covalent enzyme modification and a site for chain lengthening

Biochemistry

Volumn 36, Issue 27, 1997, Pages 8349-8358

  Preisig Muller R ^a   Gehlert, R ^a   Melchior, F ^a   Stietz, U ^a   Kindl, H ^a  

^a PHILIPPS UNIVERSITY MARBURG   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

HYBRID PROTEIN; MALONYL COENZYME A; POLYKETIDE;

ANION EXCHANGE CHROMATOGRAPHY; ARTICLE; CARBOXY TERMINAL SEQUENCE; CATALYSIS; DECARBOXYLATION; ENZYME ACTIVITY; ENZYME ISOLATION; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; PLANT; POLYACRYLAMIDE GEL ELECTROPHORESIS; PRIORITY JOURNAL; PROTEIN ANALYSIS;

ACYL COENZYME A; ACYLTRANSFERASES; AFFINITY LABELS; AMINO ACID SEQUENCE; BINDING SITES; CARBON DIOXIDE; ETHYLMALEIMIDE; KINETICS; MALONYL COENZYME A; MULTIENZYME COMPLEXES; MUTAGENESIS; PEPTIDE FRAGMENTS; PHENYLPROPIONATES; PLANTS; STILBENES; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 0039649989     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi970368h     Document Type: Article

References (39)

1. Alberts, A. W., Bell, R. M., & Vagelos, P. R. (1972) J. Biol. Chem. 247, 3190-3198.
2. Amy, C. M., Witkowski, A., Naggert, J., Williams, B., Randhawa, Z., & Smith, S. (1989) Proc. Natl. Acad. Sci. U.S.A. 86, 3114-3118.
3. Boyer, P. D. (1954) J. Am. Chem. Soc. 76, 4331-4334.
4. Bridges, A. J., & Knowles, J. R. (1974) Biochem. J. 143, 663-668.
5. Dimroth, P., Ringelmann, E., & Lynen, F. (1976) Eur. J. Biochem. 68, 591-596.
6. Feussner, I., & Kindl, H. (1994) Planta 194, 22-28.
7. Fischer, R., & Hain, R. (1994) Curr. Opin. Biotechnol. 5, 125-130.
8. Gehlert, R., Schöppner, A., & Kindl, H. (1990) Mol. Plant-Microbe Interact. 3, 444-449.
9. Hain, R., Reif, H. J., Krause, E., Langebartels, R., Kindl, H., Vornam, B., Wiese, W., Schmelzer, E., Schreier, P. H., Stöcker, R. H., Thomzik, J. E., & Stenzel, K. (1993) Nature 361, 153-156.
10. Hart, J. H. (1981) Annu. Rev. Phytopathol. 19, 437-458.
11. Höhne, M., Nellen, A., Schwennesen, K., & Kindl, H. (1996) Eur. J. Biochem. 241, 6-11.
12. Hopwood, D. A. (1990) Annu. Rev. Genet. 24, 37-66.
13. Hrazdina, G., Kreuzaler, F., Hahlbrock, K., & Grisebach, H. (1976) Arch. Biochem. Biophys. 175, 392-399.
14. Hutchinson, C. R., & Fujii, I. (1995) Annu. Rev. Microbiol. 49, 201-238.
15. Jang, S.-H., Cheesbrough, T. M., & Kolattukudy, P. E. (1989) J. Biol. Chem. 264, 3500-3505.
16. Kattar-Cooley, P. A., Wang, H. H., Mende-Mueller, L. M., & Miziorko, H. M. (1990) Arch. Biochem. Biophys. 283, 523-529.
17. Katz, L., & Donadio, S. (1993) Annu. Rev. Microbiol. 47, 875-912.
18. Kauppinen, S., Siggaard-Andersen, M., & von Wettstein-Knowles, P. (1988) Carlsberg Res. Commun. 53, 357-370.
19. Kindl, H. (1985) in Biosynthesis and Biodegradation of Wood Components (Higuchi, T., Ed.) pp 349-377, Academic Press, New York.
20. Kresze, G.-B., Steber, L., Oesterhelt, D., & Lynen, F. (1977) Eur. J. Biochem. 79, 191-199.
21. Kreuzaler, F., Light, R. J., & Hahlbrock, K. (1978) FEBS Lett. 94, 175-178.
22. Laemmli, U. K. (1970) Nature 227, 680-684.
23. Lanz, T., Tropf, S., Marner, F. J., Schröder, J., & Schröder, G. (1991) J. Biol. Chem. 266, 9971-9976.
24. Liswidowati, Melchior, F., Hohmann, F., Schwer, B., & Kindl, H. (1991) Planta 183, 307-314.
25. Lowry, O. H., Rosebrough, N. J., Farr, A. L., & Randall, R. J. (1951) J. Biol. Chem. 193, 265-275.
26. Melchior, F., & Kindl, H. (1990) FEBS Lett. 268, 17-20.
27. Melchior, F., & Kindl, H. (1991) Arch. Biochem. Biophys. 288, 552-557.
28. Mohamed, A. H., Chirrala, S. S., Mody, N. H., Huang, W. Y., & Wakil, S. J. (1988) J. Biol. Chem. 263, 12315-12325.
29. Morisaki, N., Funabashi, H., Shimazawa, R., Furukawa, J., Kawaguchi, A., Okuda, S., & Iwasaki, S. (1993) Eur. J. Biochem. 211, 111-115.
30. Omura, S. (1976) Bacteriol. Rev. 40, 681-697.
31. Preisig-Müller, R., Gnau, P., & Kindl, H. (1995) Arch. Biochem. Biophys. 317, 201-207.
32. Reinecke, T., & Kindl, H. (1994) Phytochemistry 35, 63-66.
33. Schöppner, A., & Kindl, H. (1984) J. Biol. Chem. 259, 6806-6811.
34. Schröder, G., Brown, J. W. S., & Schröder, J. (1988) Eur J. Biochem. 172, 161-169.
35. Schröder, J., & Schröder, G. (1990) Z. Naturforsch. 45c, 1-8.
36. Stöckigt, J., & Zenk, M. H. (1975) Z. Naturforsch. 30c, 352-358.
37. Subramani, S., & Schachman, H. K. (1981) J. Biol. Chem. 256, 1255-1262.
38. Whitmore, F. C., & Woodward, G. E. (1932) in Organic Syntheses (Gilman, H., Ed.) Vol. 1, pp 153-154, J. Wiley & Sons, New York.
39. Whitmore, F. C., Hamilton, F. H., & Thurman, N. (1932) in Organic Syntheses (Gilman, H., Ed.) Vol. 1, pp 505-506, J. Wiley & Sons, New York.