Application of centrifugal counter-current chromatography to the separation of macrolide antibiotic analogues. II. Determination of partition coefficients in comparison with the shake-flask method

Journal of Liquid Chromatography and Related Technologies

Volumn 23, Issue 9, 2000, Pages 1365-1376

  Wang Fan, Weizheng ^a   Küsters, Ernst ^a   Mak, Ching Pong ^a   Wang, Ying ^a  

^a NOVARTIS PHARMA AG   (Switzerland)

Author keywords

[No Author keywords available]

Indexed keywords

ASCOMYCIN; ASCOMYCIN DERIVATIVE; MACROLIDE; RAPAMYCIN; RAPAMYCIN DERIVATIVE; TACROLIMUS; UNCLASSIFIED DRUG;

APPARATUS; ARTICLE; COUNTER CURRENT CHROMATOGRAPHY; DRUG DETERMINATION; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; PARTITION COEFFICIENT;

EID: 0039174323     PISSN: 10826076     EISSN: None     Source Type: Journal    
DOI: 10.1081/JLC-100100420     Document Type: Article

References (25)

1. W. D. Conway, Counter Current Chromatography - Apparatus, Theory, and Applications, VCH Publishers, Inc., New York, 1990.
2. W. Wang-Fan, E. Kuesters, O. Lohse, C. Mak, Y. Wang, J. Chromatogr. A, 864, 69-76 (1999).
3. A. Leo, C. Hansch, D. Elkins, Chem. Rev., 71, 525-616 (1971).
4. A. Mersey, A. P. Hill, R. M. Hyde, D. J. Livingstone, Quant. Struct.-Act. Relat., 8, 288 (1989).
5. T. Braumann, J. Chromatogr., 373, 191-225 (1986).
6. P. Vallat, W. Fan, N. El Tayar, P. -A. Carrupt, B. Testa, J. Liq. Chromatogr, 15, 2133-2151 (1992).
7. C. Horvath, Techniques in Liquid Chromatography, Wiley, New York, (1982).
8. N. El Tayar, A. Tsantili-Kakoulidou, T. Roethlisberger, B. Testa, J. Gal, J. Chromatogr., 439, 237-244 (1988).
9. A. Bechalany, T. Roethlisberger, N. El Tayar, B. Testa, J. Chromatogr., 473, 115-124 (1989).
10. F. Gago, J. Alvarez-Builla, J. Elguero, J. Chromatogr., 360, 247-251 (1986).
11. T. Tanimura, J. J. Pisano, Y. Ito, R. L. Bowman, Science, 169, 54 (1970).
12. H. Terada, Y. Kosuge, N. Nakaya, W. Murayama, Y. Nunogaki, K. -I. Nunogaki, Chem. Pharm. Bull., 35, 5010-5014 (1987).
13. P. Vallat, N. El Tayar, B. Testa, I. Slavanin, A. Marston, K. Hostettmann, J. Chromatogr., 504, 411-419 (1990).
14. N. El Tayar, R. -S. Tsai, P. Vallat, C. Altomare, B. Testa, J. Chromatogr., 556, 181-194 (1991).
15. S. Omura, Macrolide Antibiotics, Chemistry, Biology and Practice, Academic Press, Orlando, 1984.
16. T. Kino, H. Hatanaka, M. Hashimoto, M. Nishiyama, T. Goto, M. Okuhara, M. Kohsaka, H. Aoki, H. Imanaka, J. Antibiotics, 40, 1249-1255 (1987).
17. H. Hatanaka, T. Kino, S. Miyata, N. Inamura, A. Kuroda, T. Goto, H. Tanaka, M. Okuhara, J. Antibiotics, 41, 1592-1601 (1988).
18. A. B. Smith, K. J. Hale, L. M. Laakso, K. Chen, A. Riera, Tetrahedron Lett., 30, 6963-6966 (1989).
19. K. Baumann, Eur. Pat. Appl., 52pp. EP 569337 A1 93110.
20. S. N. Sehgal, H. Baker, C. Vezina, J. Antibiot., 28, 727-732 (1975).
21. S. Cottens, R. Sedrani, PCT Int. Appl., 43pp. WO 9409010 A1 940428.
22. S. Cottens, R. Sedrani, PCT Int. Appl., 37pp. WO 9641807 A1 961227.
23. I. A. Sutherland, Laboratory Practice, 37-41 (1987).
24. A. Berthod, D. W. Armstrong, J. Liq. Chromatogr., 11, 1187-1204 (1988).
25. N. El Tayar, A. Marston, A. Bechalany, K. Hostettmann, B. Testa, J. Chromatogr., 469, 91-99 (1989).