First synthesis of C-phenyl N-tert-butyl [15N]nitrone (PBN-15N) for the EPR spin trapping methodology

Zeitschrift fur Naturforschung - Section B Journal of Chemical Sciences

Volumn 51, Issue 1, 1996, Pages 139-143

  Zhang, Yong Kang ^a  

^a OKLAHOMA MEDICAL RESEARCH FOUNDATION   (United States)

Author keywords

Aminoxyl (nitroxide); C phenyl n tert butyl 15 nitrone; EPR spin trapping; Nitrone; Spin trap

Indexed keywords

CHLORINE COMPOUNDS; PARAMAGNETIC RESONANCE;

ELECTRON PARAMAGNETIC RESONANCES (EPR); HYPERFINE SPLITTINGS; NITRONES; NITROXIDES; PHOSPHATE BUFFERS; SPIN TRAP; SPIN TRAPPING; SYNTHETIC METHODS;

ELECTRON SPIN RESONANCE SPECTROSCOPY;

EID: 0038975730     PISSN: 09320776     EISSN: None     Source Type: Journal    
DOI: 10.1515/znb-1996-0125     Document Type: Article

References (19)

1. a) A. H. Beth, S. D. Venkataramu, K. Balasubramanian, L. R. Dalton, B. H. Robinson, D. E. Pearson, C. R. Park, J. H. Park, Proc. Natl. Acad. Sci. USA 78, 967 (1981);
2. b) J. F. W. Keana, L. Lex, J. S. Mann, J. M. May, J. H. Park, S. P. Pou, V. S. Prabhu, G. M. Rosen, B. J. Sweetman, Y. Wu, Pure Appl. Chem. 62, 201 (1990);
3. c) K. Makino, S. Nagahara, Y. Konishi, M. Mukae, H. Ide, A. Murakami, Free Rad. Res. Comms. Supplement 19 (S1), S109 (1993);
4. d) S. P. Pou, G. M. Rosen, Y. Wu, J. F. W. Keana, J. Org. Chem. 55, 4438 (1990).
5. 14N will be used to refer to normal PBN in the description of this work.
6. a) E. G. Janzen, Acc. Chem. Res. 4, 31 (1971);
7. b) W. A. Pryor, Free Rad. Biol. Med. 17, 451 (1994);
8. c) L. A. Reinke, D. R. Moore, C. M. Hague, P. B. McCay, Free Rad. Res. 21, 213 (1994);
9. d) D. D. Bono, W.-D. Yang, M. C. R. Symons, Free Rad. Res. 20, 327 (1994);
10. e) M. G. Hartell, G. Borzone, T. L. Clanton, L. J. Berliner, Free Rad. Biol. Med. 17, 467 (1994);
11. f) E. G. Janzen, R. A. Towner, P. H. Krygsman, E. K. Lai, J. L. Poyer, G. Brueggemann, P. B. McCay, Free Rad. Res. Commun. 9, 353 (1990);
12. g) P. B. McCay, E. K. Lai, J. L. Poyer, C. M. DuBose, E. G. Janzen, J. Biol. Chem. 259, 2135 (1984);
13. h) B. Kalyanaraman, R. P. Mason, E. Perez-Reyes, C. F. Chignell, C. R. Wolf, R. M. Philpot, Biochem. Biophys. Res. Commun. 89, 1065 (1979):
14. i) J. L. Poyer, R. A. Floyd, P. B. McCay, E. G. Janzen, E. R. Davis, Biochim. Biophys. Acta 539, 402 (1978).
15. P. Kovacic, S. S. Chaudhary, Org. Syn. 48, 4 (1968).
16. J. W. Strand, P. Kovacic, J. Am. Chem. Soc. 95, 2977 (1973).
17. A. Calder, A. R. Forrester, S. P. Hepburn, Org. Syn. 52, 77 (1972).
18. D. L. Haire, U. M. Oehler, P. H. Krygsman, E. G. Janzen, J. Org. Chem. 53, 4535 (1988).
19. CRC Handbook of Chemistry and Physics, the 70th edition; CRC Press: Florida, p. B-229 (1989-1990).