DNA deamination: Not just a trigger for antibody diversification but also a mechanism for defense against retroviruses

Nature Immunology

Volumn 4, Issue 7, 2003, Pages 641-643

  Harris, Reuben S ^a   Sheehy, Ann M ^b   Craig, Heather M ^b   Malim, Michael H ^b   Neuberger, Michael S ^a  

^a MRC LABORATORY OF MOLECULAR BIOLOGY   (United Kingdom)

^b KING'S COLLEGE LONDON   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

COMPLEMENTARY DNA; CYTIDINE DEAMINASE; CYTOSINE; DOUBLE STRANDED DNA; URACIL; VIRUS ANTIBODY; VIRUS DNA;

ANTIBODY RESPONSE; ANTIBODY SPECIFICITY; ARTICLE; DEAMINATION; DNA REPLICATION; DNA SYNTHESIS; ENZYME ACTIVATION; GENE LOCUS; GENE MUTATION; GENETIC ANALYSIS; GENETIC VARIABILITY; HOST RESISTANCE; HUMAN; IMMUNE RESPONSE; IMMUNOGLOBULIN GENE; IMMUNOSURVEILLANCE; INFECTION RESISTANCE; MOLECULAR MECHANICS; NONHUMAN; NUCLEIC ACID BASE SUBSTITUTION; PRIORITY JOURNAL; RETROVIRUS; REVERSE TRANSCRIPTION; VIRUS PARTICLE; VIRUS REPLICATION;

ANTIBODY DIVERSITY; CYTIDINE DEAMINASE; DEAMINATION; DNA; DNA, COMPLEMENTARY; HUMANS; IMMUNITY, NATURAL; NUCLEOSIDE DEAMINASES; PROTEINS; REPRESSOR PROTEINS; RETROVIRIDAE INFECTIONS; RNA EDITING;

EID: 0038825009     PISSN: 15292908     EISSN: None     Source Type: Journal    
DOI: 10.1038/ni0703-641     Document Type: Article

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