Usefulness of endoscopic biopsy using immunostaining of p53 and Ki-67 in tumors of the ampulla of Vater

Pathology International

Volumn 53, Issue 6, 2003, Pages 361-370

  Kubota, Kensuke ^a,b   Kakuta, Yukio ^a   Kawamura, Shunji ^a   Saito, Shuichi ^b   Seki, Hideichi ^c   Kuniyoshi, Takashi ^c  

^a YOKOHAMA ROSAI HOSPITAL   (Japan)

^b Togane Prefectural Hospital   (Japan)

^c Higashimatsudo Hospital   (Japan)

Author keywords

Endoscopic biopsy; Immunostaining; p53 protein; Tumors of the ampulla of Vater

Indexed keywords

KI 67 ANTIGEN; PROTEIN P53; TUMOR MARKER;

ADENOCARCINOMA; ADENOMA; ADULT; AGED; ARTICLE; BILE DUCT TUMOR; BIOPSY; CALCULATION; CANCER DIAGNOSIS; CANCER GRADING; CANCER STAGING; CELL LABELING; CELL TYPE; CLINICAL ARTICLE; CONTROLLED STUDY; CORRELATION ANALYSIS; DIAGNOSTIC VALUE; DIFFERENTIAL DIAGNOSIS; ENDOSCOPIC BIOPSY; ENZYME IMMUNOASSAY; FEMALE; GASTROINTESTINAL ENDOSCOPY; HISTOPATHOLOGY; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; MALE; MALIGNANT TRANSFORMATION; METABOLISM; PATHOLOGY; PRIORITY JOURNAL; PROGNOSIS; PROTEIN EXPRESSION; TUMOR DIFFERENTIATION; TUMOR RECURRENCE; VATER PAPILLA; VATER PAPILLA CARCINOMA; VATER PAPILLA TUMOR;

ADENOCARCINOMA; ADENOMA; AGED; AMPULLA OF VATER; BIOPSY; COMMON BILE DUCT NEOPLASMS; ENDOSCOPY, GASTROINTESTINAL; FEMALE; HUMANS; IMMUNOENZYME TECHNIQUES; KI-67 ANTIGEN; MALE; NEOPLASM RECURRENCE, LOCAL; NEOPLASM STAGING; PROGNOSIS; TUMOR MARKERS, BIOLOGICAL; TUMOR SUPPRESSOR PROTEIN P53;

EID: 0038824867     PISSN: 13205463     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1440-1827.2003.01482.x     Document Type: Article

References (24)

1. Yamaguchi K, Enjoji M, Kimura K. Endoscopic biopsy has limited accuracy in diagnosis of ampullary tumor. Gastrointest Endosc 1990; 36: 588-92.
2. Binmoeller KF et al. Endoscopic snare excision of benign adenoma of the papilla of vater. Gastrointestinal Endosc 1993; 39: 127-31.
3. Yamaguchi K, Enjoji M. Carcinoma of the ampulla of Vater. A clinicopathologic study and pathologic staging of 109 cases of carcinoma and 5 cases of adenoma. Cancer 1987; 59: 506-15.
4. Tasaka K, Watanabe H, Enjoji M, Carcinoma in the region of the duodenal papilla: a histopathologic study [in Japanese with English abstract]. Fukuoka Acta Med 1977; 68: 20-44.
5. Seifert E, Schulte F, Stolte M. Adenoma and carcinoma of the duodenum and papilla of vater: a clinicopathologic study. Am J Gastroenterol 1992; 87: 37-42.
6. Younes M, Riley S, Genta RM et al. P53 protein accumulation in tmor of the papilla of Vater. Cancer 1995; 76: 1150-4.
7. Sato T, Konishi K, Kimura H, et al. Adenoma and tiny carcinoma in adenoma of the papilla of Vater-p53 and PCNA. Hepatogastroenterology 1999; 46: 1959-62.
8. Zhao B, Kimura W, Futakawa N, et al.P53 and p21/Waf1 protein expression and K-ras codon 12 mutation in carcinoma of the papilla of Vater. Am J Gastroenterol 1999; 94: 2128-34.
9. Park SH, Kim YI, Park YH, et al. Clinicopathologic correlation of p53 protein over expression in adenoma and carcinoma of the ampulla of Vater. World J Surg 2000; 24: 54-9.
10. Yi-Ming Shyr, Cheng-HsiSu & Li-Hwa WU et al. Prognostic value of MIB-1 index and DNA ploidy in resectable ampulla of Vater carcinoma. Ann Surg 1999; 229: 523-37.
11. Watanabe H, Ajioka Y, Yamaguchi Y et al. Correlation of adenoma of the large inteitine and cancer. [in Jap] Stomach Intestine (Tokyo) 1989; 24: 253-9.
12. Tumor of the Gallbladder Extrahepatic bile Duct and Ampulla of Vater. Atlas of Tumor Pathology, 3rd edn. AFIP, Washington DC 2001, 273-7.
13. Japanese Society of Biliary Surgery. General Rules for Surgical and Pathological Studies on Cancer of the Biliary Tract, 4th edn. Tokyo. Japanese Society of Biliary Surgery 1997, 55-61.
14. Takashima M, Ueki T, Nagai E et al. Carcinoma of the Ampulla of Vater Associated With or Without Adenoma: Clinicopathologic Analysis of 198 Cases With Reference to p53 and ki-67 Immunohistochemical Expressions. Mod Pathol 2000; 13: 1300-7.
15. Ahnen DJ, Feigl P, Quan G et al. Ki-ras mutation and p53 over expression predict the clinical behavior of colorectal cancer: a southwest oncology group study. Cancer Res 1998; 58: 1149-58.
16. Kamisawa T, Tabata I, T.Izawa et al. Study of ampullary carcinoma uncomfirmed by initial endoscopical biopsy [in Japanese with English abstract]. J Japan Biliary Assoc 1989; 3: 71-5.
17. Yamano M, Watanabe H, Kurosaki R et al. Pathological feature of tumor of the papilla of Vater [in Japaneset]. J Gastoroenterol Imaging 2001; 3: 159-71.
18. Baker SJ, Preisinger AC, Jessup JM et al. P53 gene mutations occur in combination with 17p alleic deletions as late events in colorectal tumorigenesis. Cancer Res 1990; 50: 7717-22.
19. Itoi T, Watanabe H, Yosida M et al. Correlation of p53 protein expression with gene mutation in gallbladder carcinomas. Pathol Int 1997; 47: 525-333.
20. Cattoretti G, Becker MHG, Key G et al. Monoclonal antibodies against recombinant parts of the ki-67 antigen (MIB-1 and MIB-3) detetect proliferating cells in microwave-processed formalin fixed paraffin sections. J Pathol 1992; 168: 357-63.
21. Tatsuo A. A clinicopathological study of carcinoma of the papilla Vater with special reference to factors influencing its prognosis and recurrent mode [in Japanese]. The Jap J Gastroenterol Surgery 1989; 22: 2009-17.
22. Howe JR, Klimstra DS, Moccia RD et al. Factors predictive of survival in ampullary carcinoma: results in 123 patients between 1983 and 1995. Ann Surg 1998; 228: 87-94.
23. Matubayashi H, Watanabe H, Yamaguchi T et al. Differences in mucus and K-ras mutation in relation to phenotypes of tumors of the papilla of vater. Cancer 1999; 86: 596-607.
24. Vaidya P, Yosida T, Sakakura T, Yatani R, Noguchi T, Kawarada. Combined analysis of expression of c-erbB-2, Ki-67 antigen, and tenascin provides a better prognostic indicator of carcinoma of the papilla of Vater. Pancreas 1996; 12: 196-201.