Low dose methotrexate osteopathy in a patient with polyarticular juvenile idiopathic arthritis [2]

Annals of the Rheumatic Diseases

Volumn 62, Issue 6, 2003, Pages 588-589

  Rudler, M ^a   Pouchot, J ^a   Paycha, F ^a   Gentelle, S ^a   Grasland, A ^a   Vinceneux, P ^a  

^a HÔPITAL LOUIS MOURIER   (France)

Author keywords

[No Author keywords available]

Indexed keywords

CORTICOSTEROID; METHOTREXATE; PREDNISONE; TECHNETIUM 99M;

ADULT; BLOOD TOXICITY; BONE DISEASE; BONE SCINTISCANNING; CASE REPORT; CORTICOSTEROID THERAPY; FEMALE; FRACTURE; HUMAN; JUVENILE RHEUMATOID ARTHRITIS; LEG PAIN; LETTER; LIVER TOXICITY; LOW DRUG DOSE; OSTEOPENIA; PRIORITY JOURNAL;

ADULT; ANTIRHEUMATIC AGENTS; ARTHRITIS, JUVENILE RHEUMATOID; FEMALE; FRACTURES, SPONTANEOUS; HUMANS; METHOTREXATE; OSTEOPOROSIS;

EID: 0038823923     PISSN: 00034967     EISSN: None     Source Type: Journal    
DOI: 10.1136/ard.62.6.588     Document Type: Letter

References (8)

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3. Stevens H, Jacobs JWG, Van Rijk PP, De Klerk JMH. Methotrexate osteopathy demonstrated by technetium-99m HDP bone scintigraphy. Clin Nucl Med 2001;26:389-91.
4. Wijnands M, Burgers. Stress fracture in long term methotrexate treatment for psoriatic arthritis. Ann Rheum Dis 2001;60:736-8.
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7. Buckley LM, Leib ES, Cartularo KS, Vacek PM, Cooper SM. Effects of low dose methotrexate on the bone mineral density of patients with rheumatoid arthritis. J Rheumatol 1997;24:1489-94.
8. Uehara R, Suzuki Y, Ichikawa Y. Methotrexate (MTX) inhibits osteoblastic differenciation in vitro: possible mechanism of MTX osteopathy. J Rheumatol 2001;28:251-6.