Acute hypokalemic tetraparesis induced by intravenous methotrexate

Journal of Clinical Oncology

Volumn 21, Issue 9, 2003, Pages 1896-1897

  Thuss Patience, Peter C ^a,b   Peters, Uwe ^a,b   Jurkat Rott, Karin ^a,b   Pink, Daniel ^a,b   Kretzschmar, Albrecht ^a,b   Dörken, Bernd ^a,b   Reichardt, Peter ^a,b  

^a CHARITÉ UNIVERSITÄTSMEDIZIN BERLIN   (Germany)

^b UNIVERSITY OF ULM   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

ANTINEOPLASTIC ANTIMETABOLITE; METHOTREXATE;

ADULT; CASE REPORT; CHEMICALLY INDUCED DISORDER; HUMAN; HYPOKALEMIA; INTRAVENOUS DRUG ADMINISTRATION; LETTER; MALE; OSTEOSARCOMA; PARESIS;

ADULT; ANTIMETABOLITES, ANTINEOPLASTIC; HUMANS; HYPOKALEMIA; INFUSIONS, INTRAVENOUS; MALE; METHOTREXATE; OSTEOSARCOMA; PARESIS;

EID: 0038811734     PISSN: 0732183X     EISSN: 15277755     Source Type: Journal    
DOI: 10.1200/JCO.2003.99.008     Document Type: Letter

References (8)

1. Bleyer AW: Neurologic sequelae of methotrexate and ionizing radiation: A new classification. Cancer Treat Rep 65:89-98, 1981 (suppl 1)
2. Massenkeil G, Späth-Schwalbe E, Flath B, et al: Transient tetraparesis after intrathecal and high-dose systemnic methotrexate. Ann Hematol 77:239-242, 1998
3. Jaffe N, Takaue Y, Anzai T, et al: Transient neurologic disturbances induced by high-dose methotrexate treatment. Cancer 56:1356-1360, 1985
4. Allen JC, Rosen G, Metha M, et al: Leukencephalopathy following high dose IV methotrexate chemotherapy with leukovorin rescue. Cancer Treat Rep 64:1261-1273, 1980
5. Pollock RJ, Kaufmann S: Dihydrofolate reductase is present in the brain. J Neurochem 52:1804-1811, 1977
6. Friedmann PA, Kappelmann AH, Kaufmann SJ: Partial purification and characterization of tryptophan hydroxylase from rabbit hindbrain. J Biol Chem 247:4165-4173, 1972
7. Lehmann-Horn F, Jurkat-Rott K, Rudel R: Periodic paralysis: understanding channelopathies. Curr Neurol Neurosci Rep 2:61-69, 2002
8. Sternberg D, Maisonobe T, Jurkat-Rott K, et al: Hypokalaemic periodic paralysis type 2 caused by mutations at codon 672 in the muscle sodium channel gene SCN4A. Brain 124:1091-1099, 2001