Structural studies of Yersinia adhesin YadA

Advances in Experimental Medicine and Biology

Volumn 529, Issue , 2003, Pages 85-88

  Nummelin, Heli ^a   Merckel, Michael C ^a   El Tahir, Yasmin ^c   Ollikka, Pauli ^c,d   Skurnik, Mikael ^b,c   Goldman, Adrian ^a  

^a UNIVERSITY OF HELSINKI   (Finland)

^b UNIVERSITY OF HELSINKI   (Finland)

^c UNIVERSITY OF TURKU   (Finland)

^d Biotie Therapies Corp   (Finland)

Author keywords

[No Author keywords available]

Indexed keywords

ADHESIN; BACTERIAL PROTEIN; PROTEIN YADA; UNCLASSIFIED DRUG;

AMINO TERMINAL SEQUENCE; CARBOXY TERMINAL SEQUENCE; CONFERENCE PAPER; CRYSTAL STRUCTURE; CRYSTALLIZATION; CRYSTALLOGRAPHY; HOST CELL; HOST PATHOGEN INTERACTION; MOLECULAR CLONING; NONHUMAN; PRIORITY JOURNAL; PROTEIN STABILITY; PROTEIN STRUCTURE; YERSINIA ENTEROCOLITICA;

ADHESINS, BACTERIAL; CLONING, MOLECULAR; CRYSTALLOGRAPHY, X-RAY; MACROMOLECULAR SUBSTANCES; MODELS, MOLECULAR; PROTEIN STRUCTURE, SECONDARY; RECOMBINANT PROTEINS; YERSINIA ENTEROCOLITICA;

BACTERIA (MICROORGANISMS); YERSINIA; YERSINIA ENTEROCOLITICA;

EID: 0038807568     PISSN: 00652598     EISSN: None     Source Type: Book Series    
DOI: None     Document Type: Conference Paper

References (14)

1. El Tahir, Y., Kuusela, P., and Skurnik, M., 2000, Functional mapping of the Yersinia enterocolitica adhesin YadA. Identification of eight NSVAIG - S motifs in the aminoterminal half of the protein involved in collagen binding., Mol. Microbiol. 37(1), 192-206.
2. El Tahir, Y., and Skurnik M., 2001, Mini review: YadA, multifaceted Yersinia adhesin, Int. J. Med. Microbiol. 291, 209-218.
3. Gripenberg-Lerche, C., Skurnik, M., and Toivanen P., 1995, Role of YadA-mediated collagen binding in arthritogenicity of Yersinia enterocolitica serotype O:8 experimental studies with rats, Infect. Immun. 63, 3222-3226.
4. Heesemann, J., and Grüter, L., 1987, Genetic evidence that the outer membrane protein YOP1 of Yersinia enterocolitica mediates adherence and phagocytosis resistance to human ephithelial cells, FEMS Microbiol Lett. 40, 37-41.
5. Hoiczyk, E., Roggenkamp, A., Reichenbecher, M., Lupas, A. and Heesemann, J., 2000, Structure and sequence analysis of Yersinia YadA and Moraxella UspAs reveal a novel class of adhesins, Embo J. 19, 5989-5999.
6. Isberg, R., and Falkow, S., 1985, A single genetic locus encoded by Yersinia pseudotuberculosis permits invasion of cultured animals cells by Escherichia coli K-12, Nature, 317, 262-264.
7. Miller, V.L., and Falkow, S., 1988, Evidence for two genetic loci in Yersinia enterocolitica that can promote invasion of ephithelial cells, Infect. Immun. 56, 1242-1248.
8. Nummelin, H., El Tahir, Y., Ollikka, P., Skurnik, M., and Goldman A., 2002, Expression, purification and crystallization of a collagen-binding fragment of Yersinia adhesin YadA, Acta Cryst. D58: 1042-1044.
9. Otwinowski, A., and Minor, W., 1995, DENZO. Yale University, New Haven, Connecticut, USA.
10. Roggenkamp, A., Neuberger, H-R., Flügel, A., Schmoll, T., and Heesemann, J., 1995, Substitution of two histidine residues in YadA protein of Yersinia enterocolitica abrogates collagen binding, cell adherence and mouse virulence, Mol. Microbiol., 16, 1207-1219.
11. Rosqvist, R., Skurnik, M., and Wolf-Watz, H., 1988, Increased virulenve of Yersinia pseudotuberculosis by two independent mutations, Nature 334, 522-525.
12. Skurnik, M., and Toivanen, P., 1992, LcrF is the temperature-regulated activator of the yadA gene of Yersinia entrocolitica and Yersinia pseudotuberculosis, J. Bacteriol. 158, 1033-1036.
13. Tamm, A., Tarkkanen, A.M., Korhonen, T., Kuusela, P., Toivanen, P., and Skurnik, M., 1993, Hydrophobic domains affect the collagen-binding specificity and surface polymerization as well as the virulence potential of the YadA protein of Yerisinia enterocolitica, Mol. Microbiol. 10, 995-1011.
14. Terwilliger, TC., and Berendzen J., 1999, Automated MAD and MIR structure solution, Acta Cryst., D55, 849-861.