Autoregulation in the parathyroid glands by PTH/PTHrP receptor ligands in normal and uremic rats

Kidney International

Volumn 64, Issue 1, 2003, Pages 63-70

  Lewin, Ewa ^a   Garfia, Bartolome ^b   Almaden, Yolanda ^b   Rodriguez, Mariano ^b   Olgaard, Klaus ^b  

^a UNIVERSITY OF COPENHAGEN   (Denmark)

^b NONE

Author keywords

Autocrine paracrine factor; Calcium PTH curve; PTH PTHrP receptor; PTHrP; Secondary hyperparathyroidism; Uremia

Indexed keywords

CALCIUM ION; CREATININE; DNA; EGTAZIC ACID; LIGAND; MESSENGER RNA; PARATHYROID HORMONE; PARATHYROID HORMONE RELATED PROTEIN; PHOSPHORUS;

ANIMAL MODEL; ARTICLE; AUTOREGULATION; CALCIUM BLOOD LEVEL; CHRONIC KIDNEY FAILURE; CONTROLLED STUDY; CREATININE BLOOD LEVEL; DOSE RESPONSE; HYPERPARATHYROIDISM; HYPOCALCEMIA; KIDNEY DISEASE; KIDNEY FUNCTION; NONHUMAN; NUCLEOTIDE SEQUENCE; PARATHYROID GLAND; PARATHYROID HORMONE BLOOD LEVEL; PHOSPHATE BLOOD LEVEL; PRIORITY JOURNAL; RAT; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SECONDARY HYPERPARATHYROIDISM; UREMIA;

EID: 0038807534     PISSN: 00852538     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1523-1755.2003.00056.x     Document Type: Article

References (45)

1. LEWIN E, ALMADEN Y, RODRIGUEZ M, OLGAARD K: PTHrP enhances the secretory response of PTH to a hypocalcemic stimulus in rat parathyroid glands. Kidney Int 58:71-81, 2000
2. MANGIN M, WEBB A, DREYER B, et al: Identification of a cDNA encoding parathyroid hormone-like peptide from human tumor associated with humoral hypercalcemia of malignancy. Proc Natl Acad Sci USA 85:597-601, 1988
3. PHILBRICK WM, WYSOLMERSKI JJ, GALBRAITH S, et al: Defining the roles of parathyroid hormone-related protein in normal physiology. Physiol Rev 76:127-173, 1996
4. ORLOFF JJ, REDDY D, PAPP AE DE, et al: Parathyroid hormone-related protein as a prohormone: Posttranslational processing and receptor interactions. Endocr Rev 15:40-60, 1994
5. KRONENBERG HM, LEE K, LANSKE B, SEGRE GV: Parathyroid hormone-related protein and Indian hedgehog control the pace of cartilage differentiation. J Endocrinol 154:S39-S45, 1997
6. RODDA CP, KUBOTA M, HEATH JA, et al: Evidence for a novel parathyroid hormone-related protein in fetal lamb parathyroid glands and sheep placenta: Comparison with a similar protein implicated in humoral hypercalcemia of malignancy. J Endocrinol 117:261-271, 1988
7. KARAPLIS AC, VAUTOUR L: Parathyroid hormone-related peptide and the parathyroid hormone-related peptide receptor in skeletal development. Curr Opin Nephrol Hypertens 6:308-313, 1997
8. ROBINSON NR, SIBLEY CP, MUGHAL MZ, BOYD RD: Fetal control of calcium transport across the rat placenta. Pediatr Res 26:109-115, 1989
9. MACISSAC RJ, HEATH JA, RODDA CP, et al: Role of the fetal parathyroid glands and parathyroid hormone-related protein in the regulation of placental transport of calcium, magnesium and inorganic phosphate. Reprod Fertil Dev 3:447-457, 1991
10. MOSELEY JM, HAYMAN JA, DANKS JA, et al: Immunohistochemical detection of parathyroid hormone-related protein in human fetal epithelia. J Clin Endocrinol Metab 73:478-484, 1991
11. MASSFELDER T, FIASCHI-TAESCH N, STEWART AF, HELWIG JJ: Parathyroid hormone-related peptide - A smooth muscle tone and proliferation regulatory protein. Curr Opin Nephrol Hypert 7:27-32, 1998
12. AYA K, TANAKA H, ICHINOSE Y, et al: Expression of parathyroid hormone-related peptide messenger ribonucleic acid in developing kidney. Kidney Int 55:1696-1703, 1999
13. IKEDA K, WEIR EC, MANGIN M, et al: Expression of messenger ribonucleic acids encoding a parathyroid hormone-like peptide in normal human and animal tissues with abnormal expression in human parathyroid adenomas. Mol Endocrinol 2:1230-1236, 1988
14. MARTIN TJ, MOSELEY JM, WILLIAMS ED: Parathyroid hormone-related protein: Hormone and cytokine. J Endocrinol 154:S23-S37, 1997
15. CONNOR CS, DREES BM, THURSTON A, et al: Bovine parathyroid issue: A model to compare the biosynthesis and secretion of parathyroid hormone and parathyroid hormone-related peptide. Surgery 106:1057-1062, 1989
16. CONNOR C, DREES B, HAMILTON J: Parathyroid hormone-like peptide and parathyroid hormone are secreted from bovine parathyroid via different pathways. Biochim Biophys Acta 1178:81-86, 1993
17. DANKS JA, EBELING PR, HAYMAN JA, et al: Immunohistochemical localisation of parathyroid hormone-related protein in parathyroid adenoma and hyperplasia. J Pathol 161:27-33, 1990
18. MATSUSHITA H, HARA M, ENDO Y, et al: Proliferation of parathyroid cells negatively correlates with expression of parathyroid hormone-related protein in secondary parathyroid hyperplasia. Kidney Int 55:130-138, 1997
19. MATSUSHITA H, USUI M, HARA M, et al: Co-secretion of parathyroid hormone and parathyroid-hormone-related protein via a regulated pathway in human parathyroid adenoma cells. Am J Pathol 150:861-871, 1997
20. MANNSTADT M, JUPPNER H, GARDELLA TJ: Receptors for PTH and PTHrP: Their biological importance and functional properties. Am J Physiol 277:F665-F675, 1999
21. FELSENFELD AF, LLACH F: Parathyroid gland function in chronic renal failure. Kidney Int 43:771-789, 1993
22. LEWIN E, WANG W, OLGAARD K: Reversibility of experimental secondary hyperparathyroidism. Kidney Int 52:1232-1241, 1997
23. GRANT FD, CONLIN PR, BROWN EM: Rate and concentration dependence of parathyroid hormone dynamics during stepwise changes in serum ionised calcium in normal humans. J Clin Endocrinol Metab 71:370-377, 1990
24. SCHWARZ P: Dose response dependency in regulation of acute PTH (1-84) release and suppression in normal humans: A citrate and calcium infusion study. Scand J Clin Lab Invest 53:601-605, 1993
25. SCHMITT CP, HUBER D, MEHLS O, et al: Altered instantaneous and calcium-modulated oscillatory PTH secretion patterns in patients with secondary hyperparathyroidism. J Am Soc Nephrol 9:1832-1844, 1998
26. ROSENBLATT M, KRONENBERG HM, PITTS JT: Parathyroid hormone, in Endocrinology (vol 2), edited by DEGROOT LJ, Philadelphia, WB Saunders Company, 1989, pp 848-891
27. BROWN EM, GAMBA G, RICCARDI D, et al: Cloning and characterization of an extracellular Ca(2+)-sensing receptor from bovine parathyroid. Nature 366:575-580, 1993
28. NIELSEN PK, FELDT-RASMUSSEN U, OLGAARD K: A direct effect in vitro of phosphate on PTH release from bovine parathyroid tissue slices but not from dispersed parathyroid cells. Nephrol Dial Transplant 11:1762-1768, 1996
29. SCHWARZ P, SORENSEN HA, TRANSBOL I, MCNAIR P: Regulation of acute parathyroid hormone release in normal humans: Combined calcium and citrate clamp study. Am J Physiol 263:E195-E198, 1992
30. FASCITTO BH, GORR S-U, BOURDEAU AM, COHN DV: Autocrine regulation of parathyriod secretion: inhibition of secretion by chromogranin-A (secretory protein-1) and potentiation of secretion by chromogranin-A and pancreastatin antibodies. Endocrinology 127:1329-1335, 1990
31. FASCITTO BH, GORR S-U, DEFRANCO DJ, et al: Pancreastatin, a presumed product of chromogranin-A (secretory protein-1) processing, inhibits secretion from porcine parathyroid cells in culture. Endocrinology 125:1617-1622, 1989
32. FUJII Y, MOREIRA JE, ORLANDO C, et al: Endothelin as autocrine factor in the regulation of parathyroid cells. Proc Natl Acad Sci USA 88:4235-4239, 1991
33. XU GG, ROTHENBERG PL: Insulin receptor signaling in the beta-cell influences insulin gene expression and insulin content: Evidence for autocrine beta-cell regulation. Diabetes 47:1243-1252, 1998
34. ASPINWALL CA, LAKEY JRT, KENNEDY RT: Insulin-stimulated insulin secretion in single pancreatic beta cells. J Biol Chem 274:6360-6365, 1999
35. SALTIEL AR, KAHN CR: Insulin signalling and the regulation of glucose and lipid metabolism. Nature 414:799-806, 2001
36. JACKEROTT M, BAUDRY A, LAMOTHE B, et al: Endocrine pancreas in insulin receptor-deficient mouse pups. Diabetes 50:S146-S149, 2001
37. LEIBIGER B, LEIBIGER IB, MOEDE T, et al: Selective insulin signaling through A and B insulin receptors regulates transcription of insulin and glucokinase genes in pancreatic beta cells. Mol Cell 7:559-570, 2001
38. HESCH RD, BRABANT G, RITTINGHAUS EF, et al: Pulse amplitude and frequency modulation of PTH and its modulation of PTH receptors - Osteoporosis as an example of dynamic disease, in New Actions of Parathyroid Hormone, edited by MASSRY SG, FUGITA T, New York, Plenum Press, 1989, p 51
39. HARMS HM, KAPTAINA U, KULPMANN WR, et al: Pulse amplitude and frequency modulation of parathyroid hormone in plasma. J Clin Endocrinol Metab 69:843-851, 1989
40. SCHMITT CP, SCHAEFER F, BRUCH A, et al: Control of pulsatile and tonic parathyroid hormone secretion by ionized calcium. J Clin Endocrinol Metab 81:4236-4243, 1996
41. FRASER WD, LOGUE FC, CHRISTIE JP, et al: Alteration of the circadian rhythm of intact parathyroid hormone and serum phosphate in women with established postmenopausal osteoporosis. Osteoporos Int 8:121-126, 1998
42. SCHMITT CP, HUBER D, MEHLS O, et al: Altered instantaneous and calcium-modulated oscillatory PTH secretion patterns in patients with secondary hyperparathyroidism. J Am Soc Nephrol 9:1832-1844, 1998
43. FUJITA T: Parathyroid hormone in the treatment of osteoporosis. BioDrugs 15:721-728, 2001
44. DEMPSTER DW, COSMAN F, KURLAND ES, et al: Effects of daily treatment with parathyroid hormone on bone microarchitecture and turnover in patients with osteoporosis: A paired biopsy study. J Bone Miner Res 16:1846-1853, 2001
45. LEWIN E, NIELSEN PK, OLGAARD K: The calcium/parathyroid hormone concept of the parathyroid glands. Curr Opin Nephrol Hypertens 4:324-333, 1995