HPLC fingerprinting and estimation of the bioactive components of Clutia richardiana L. as a potential hypoglycemic herbal tea

Phytotherapy Research

Volumn 17, Issue 6, 2003, Pages 657-660

  Abourashed, Ehab A ^a   Ganzera, Markus ^b   Khan, Ikhlas A ^b   Khan, Shabana ^b   Mossa, Jaber S ^a   El Feraly, Farouk S ^a  

^a KING SAUD UNIVERSITY   (Saudi Arabia)

^b UNIVERSITY OF MISSISSIPPI   (United States)

Author keywords

Clutia Cluytia richardiana; Cytotoxicity; Euphorbiaceae; HPLC fingerprinting; Hypoglycemic herb; Traditional medicine

Indexed keywords

ACETONITRILE; ANTIDIABETIC AGENT; CLUTIA RICHARDIANA EXTRACT; DITERPENE; HOT WATER; METHANOL; ORGANIC SOLVENT; PLANT EXTRACT; UNCLASSIFIED DRUG;

ARTICLE; CLUTIA RICHARDIANA; CYTOTOXICITY; DRUG ACTIVITY; DRUG DETERMINATION; DRUG EFFECT; DRUG EFFICACY; DRUG ISOLATION; DRUG SAFETY; DRUG STRUCTURE; DRUG SYNTHESIS; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HPLC FINGERPRINTING; MEDICINAL PLANT; NONHUMAN; TEA;

CHROMATOGRAPHY, HIGH PRESSURE LIQUID; DITERPENES; EUPHORBIACEAE; HUMANS; HYPOGLYCEMIC AGENTS; PHYTOTHERAPY; PLANT EXTRACTS; TEA; TUMOR CELLS, CULTURED;

CLUTIA; CLUTIA RICHARDIANA; CLUYTIA; CLUYTIA RICHARDIANA; EUPHORBIACEAE;

EID: 0038802399     PISSN: 0951418X     EISSN: None     Source Type: Journal    
DOI: 10.1002/ptr.1223     Document Type: Article

References (10)

1. Borenfreund E, Puerner JA. 1985. Toxicity determined in vitro by morphological alterations and neutral red absorption, Toxicol Lett 24: 119-124.
2. Furbacher TR, Gunatilaka AA. 2001. Catalytic inhibition of topoisomerase Ilalpha by demethylzeylasterone, a 6-oxophenolic triterpenoid from Kokoona zeylanica. J Nat Prod 63: 1294-1296.
3. Lopez-Lazaro M, Martin-Cordero C, Bermejo A et al. 2001. Cytotoxic compounds from Annonaceus species as DNA topoisomerase I poisons. Anticancer Res 21: 3493-3497.
4. Mossa JS, Cassady JM, Antoun MD et al. 1985. Saudin, a hypoglycemic diterpenoid with a novel 6,7-secolabdane carbon skeleton, from Cluytia richardiana. J Org Chem 50: 916-918.
5. Mossa JS, Cassady JM, Kozlowski JF et al. 1988a. Novel 6,7-seco-6,11-cyclolabdane diterpenes from Cluytia richardiana. Tetrahedron Lett 29: 3627-3630.
6. Mossa JS, El-Denshary ESM, Hindawi R, Ageel AM. 1988b. The hypoglycaemic effect of saudin. Int J Crude Drug Res 26: 81-87.
7. Mossa JS, Muhammad I, Al-Yahya MA et al. 1996. Five new modified 6,7-secolabdane diterpenoids from Cluytia richardiana. J Nat Prod 59: 224-231.
8. Muhammad I, Mossa JS, Al-Yahya M et al. 1994a. New modified labdane diterpenoids from Cluytia richardiana. J Nat Prod 57: 248-255.
9. Muhammad I, Mossa JS, Al-Yahya MA et al. 1994b. Modified labdane diterpenoids from Cluytia richardiana. Phytochemistry 37: 1377-1381.
10. Muhammad I, Dunbar DC, Takamatsu S et al. 2001. Antimalarial, cytotoxic, and antifungal alkaloids from Duguetia hadrantha. J Nat Prod 64: 559-562.