Does ketamine or magnesium affect posttonsillectomy pain in children?

Paediatric Anaesthesia

Volumn 13, Issue 5, 2003, Pages 413-421

  O'Flaherty, Jennifer E ^a   Lin, Charles X ^a  

^a UNIVERSITY OF VIRGINIA HEALTH SYSTEM   (United States)

Author keywords

Ketamine; Magnesium; N methyl D aspartate (NMDA) receptor; Postoperative pain; Tonsillectomy

Indexed keywords

CODEINE; DEXAMETHASONE; FENTANYL; KETAMINE; MAGNESIUM SULFATE; PARACETAMOL;

ARTICLE; BLEEDING; CHILD; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DREAMING; DRUG POTENTIATION; EVALUATION; FEMALE; HUMAN; MAJOR CLINICAL STUDY; MALE; NAUSEA; PAIN ASSESSMENT; POSTOPERATIVE PAIN; POSTOPERATIVE PERIOD; PRIORITY JOURNAL; RANDOMIZATION; SEDATION; TONSILLECTOMY; VOMITING;

ACETAMINOPHEN; ANALGESICS, NON-NARCOTIC; ANALGESICS, OPIOID; ANESTHETICS, DISSOCIATIVE; CHILD; CHILD, PRESCHOOL; CODEINE; DOSE-RESPONSE RELATIONSHIP, DRUG; DOUBLE-BLIND METHOD; EXCITATORY AMINO ACID ANTAGONISTS; FEMALE; FENTANYL; HEMORRHAGE; HUMANS; KETAMINE; MAGNESIUM; MALE; PAIN MEASUREMENT; PAIN, POSTOPERATIVE; POSTOPERATIVE COMPLICATIONS; POSTOPERATIVE NAUSEA AND VOMITING; TONSILLECTOMY;

EID: 0038798488     PISSN: 11555645     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1460-9592.2003.01049.x     Document Type: Article

References (32)

1. Coderre TJ, Katz J, Vaccariono AL et al. Contribution of central neuroplasticity to pathological pain: review of clinical and experimental evidence. Pain 1993; 52: 259-285.
2. Woolf CJ, Chong MS. Preemptive analgesia-treating postoperative pain by preventing the establishment of central sensitization. Anesth Analg 1993; 77: 362-379.
3. Woolf CJ, Thompson SW. The induction and maintenance of central sensitization is dependent on N-methyl-D-aspartic acid receptor activation; implications for the treatment of post-injury pain hypersensitivity states. Pain 1991; 44: 293-299.
4. Stubhaug A, Breivik H, Eide PK et al. Mapping of punctuate hyperalgesia around a surgical incision demonstrates that ketamine is a powerful suppressor of central sensitization to pain following surgery. Acta Anaesthesiol Scand 1997; 41: 1124-1132.
5. Menigaux C, Guignard B, Fletcher D et al. Intraoperative small-dose ketamine enhances analgesia after outpatient knee arthroscopy. Anesth Analg 2001; 93: 606-612.
6. Menigaux C, Fletcher D, Dupont X et al. The benefits of intraoperative small-dose ketamine on postoperative pain after anterior cruciate ligament repair. Anesth Analg 2000; 90: 129-135.
7. Koinig H, Wallner T, Marhofer P et al. Magnesium sulfate reduces intra- and postoperative analgesic requirements. Anesth Analg 1998; 87: 206-210.
8. Fu ES, Miguel R Scharf JE. Preemptive ketamine decreases postoperative narcotic requirements in patients undergoing abdominal surgery. Anesth Analg 1997; 84: 1086-1090.
9. Tramer MR, Schneider J, Marti RA et al. Role of magnesium sulfate in postoperative analgesia. Anesthesiology 1996; 84: 340-347.
10. Roytblat L, Korotkoruchko A, Katz J et al. Postoperative pain: the effect of low-dose ketarnine in addition to general anesthesia. Anesth Analg 1993; 77: 1161-1165
11. Hannallah RS, Broadman LM, Belman AB et al. Comparison of caudal and ilioinguinal/iliohypogastric nerve blocks for control of post-orchiopexy pain in pediatric ambulatory surgery. Anesthesiology 1987; 66: 832-834.
12. Norden J, Hannallah R, Getson P et al. Concurrent validation of an objective pain scale for infants and children. Anesthesiology 1991; 75: A934.
13. Nieminen P, Tolonen U, Lopponen H et al. Snoring children: factors predicting sleep apnea. Acta Otolaryngol Suppl 1997; 529: 190-194.
14. Aldrete JA, Kroulik D. A postanesthetic recovery score. Anesth Analg 1970; 49: 924-934.
15. O'Flaherty JE, Lin CX, Salmons VA et al. Effects of preemptive administration of NMDA receptor antagonists on pain after tonsillectomy m children. Anesthesiology 2000; 93: A1265.
16. Rosen GM, Muckle RP, Mahowald MW et al. Postoperative respiratory compromise in children with obstructive sleep apnea syndrome: can it be anticipated? Pediatrics 1994; 93: 784-788.
17. McColley SA, April MM, Carroll JL et al. Respiratory compromise after adenotonsillectomy in children with obstructive sleep apnea. Arch Otolaryngol Head Neck Surg 1992; 118: 940-943.
18. Liu HT, Hollmann MW, Liu WH et al. Modulation of NMDA receptor function by ketamine and magnesium: Part I. Anesth Analg 2001; 92: 1173-1181.
19. Suzuki M, Tsueda K, Lansing PS et al. Small-dose ketamine enhances morphine-induced analgesia after outpatient surgery. Anesth Analg 1999; 89: 98-103.
20. Wilder-Smith OH, Arendt-Nielsen L, Gaumann D et al. Sensory changes and pain after abdominal hysterectomy: a comparison of anesthetic supplementation with fentanyl versus magnesium or ketamine. Anesth Analg 1998; 86: 95-101.
21. Kawamata T, Omote K, Kawamata M et al. Premedication with oral dextromethorphan reduces postoperative pain after tonsillectomy. Anesth Analg 1998; 86: 594-597.
22. Henderson DJ, Withington BS, Wilson JA et al. Perioperative dextromethorphan reduces postoperative pain after hysterectomy. Anesth Analg 1999; 89: 399-402.
23. Chia YY, Liu K, Chow LH et al. The preoperative administration of intravenous dextromethorphan reduces postoperative morphine consumption. Anesth Analg 1999; 89: 748-752.
24. Wu CT, Yu JC, Liu ST et al. Preincisional dextromethorphan treatment for postoperative pain management after upper abdominal surgery. World J Surg 2000; 24: 512-517.
25. Rose JB, Cuy R, Cohen DE et al. Preoperative oral dextromethorphan does not reduce pain or analgesic consumption in children after adenotonsillectomy. Anesth Analg 1999; 88: 749-753.
26. Ko SH, Lim HR, Kim DC et al. Magnesium sulfate does not reduce postoperative analgesic requirements. Anesthesiology 2001; 95: 640-646.
27. Mathisen LC, Aasbo V, Raeder J. Lack of pre-emptive analgesic effect of (R)-ketamine in laparoscopic cholecystectomy. Acta Anaesthesiol Scand 1999; 43: 220-224.
28. Adam F, Libier M, Oszustowicz T et al. Preoperative small-dose ketamine has no preemptive analgesic effect in patients undergoing total mastectomy. Anesth Analg 1999; 89: 444-447.
29. McConaghy PM, McSorley P, McCaughey W et al. Dextromethorphan and pain after total abdominal hysterectomy. Br J Anaesth 1998; 81: 731-736.
30. Wilder-Smith CH, Knopfli R, Wilder-Smith OH. Perioperative magnesium infusion and postoperative pain. Acta Anaesthesiol Scand 1997; 41: 1023-1027.
31. Smedje H, Broman JE, Hetta J. Parents' reports of disturbed sleep in 5-7-year-old Swedish children. Acta Paediatr Scand 1999; 88: 858-865.
32. Marcus RJ, Victoria BA, Rushman SC et al. Comparison of ketamine and morphine for analgesia after tonsillectomy in children. Br J Anaesth 2000; 84: 739-742.