Effect of dexamethasone on growth inhibition and chondrogenic maturation of human chondrosarcoma

Journal of Orthopaedic Science

Volumn 8, Issue 3, 2003, Pages 341-345

  Kawashima, Hiroyuki ^a   Ogose, Akira ^a   Hayami, Tadashi ^a   Yamagiwa, Hiroshi ^a   Hatano, Hiroshi ^a   Hotta, Tetsuo ^a   Endo, Naoto ^a  

^a NIIGATA UNIVERSITY GRADUATE SCHOOL OF MEDICAL AND DENTAL SCIENCES   (Japan)

Author keywords

Chondrogenic maturation; Chondrosarcoma; Dexamethasone; Growth inhibition

Indexed keywords

COLLAGEN; DEXAMETHASONE; MESSENGER RNA;

ANIMAL CELL; ARTICLE; CANCER INHIBITION; CELL DIFFERENTIATION; CELL MATURATION; CELL SHAPE; CHONDROGENESIS; CHONDROSARCOMA; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG EFFECT; GROWTH RATE; HUMAN; HUMAN CELL; IN VITRO STUDY; IN VIVO STUDY; MOUSE; NONHUMAN; NORTHERN BLOTTING; NUDE MOUSE; PHASE CONTRAST MICROSCOPY; TUMOR CELL LINE;

EID: 0038797800     PISSN: 09492658     EISSN: None     Source Type: Journal    
DOI: 10.1007/s10776-003-0650-y     Document Type: Article

References (25)

1. Baxter JD, Forsham PJ. Tissue effects of glucocorticoids. Am J Med 1972;53:573-89.
2. Chomczynski P, Sacchi N. Single-step methods of RNA isolation by acid guanidnium thiocyanate-phenol-chloroform extraction. Anal Biochem 1987;162:156-9.
3. Distelhorst CW. Glucocorticosteroids induce DNA fragmentation in human lymphoid leukemia cells. Blood 1988;72:1305-9.
4. Dorfman HD, Czerniak B. Bone cancers. Cancer 1995;75:203-10.
5. Enomoto H, Enomoto-Iwamoto M, Iwamoto M, et al. Cbfa1 is a positive regulatory factor in chondrocyte maturation. J Biol Chem 2000;275:8695-702.
6. 3 on cartilage differentiation in a clonal chondrogenic cell population. Endocrinology 1989;125: 2103-10.
7. Gustafsson JA, Carlstedt-Duke J, Poellinger L, et al. Biochemistry, molecular biology, and physiology of the glucocorticoid receptor. Endocr Rev 1987;8:185-234.
8. Howard DD, Czerniak B. Malignant cartilage tumors. St. Louis: Mosby; 1998. p. 353-440.
9. Kato Y, Gospodarowicz D. Stimulation by glucocorticoid of the synthesis of cartilage-matrix proteoglycans produced by rabbit costal chondrocytes in vitro. J Biol Chem 1985;260:2364-73.
10. Koedam JA, Hoogerbrugge CM, Van Buul-Offers SC. Differential regulation of IGF-binding proteins in rabbit costal chondrocytes by IGF-I and dexamethasone. J Endocrinol 2000; 165:557-67.
11. Kudawara I, Ueda H, Yoshikawa H, et al. In vivo inhibition of tumour growth by dexamethasone in murine osteosarcomas. Eur J Cancer 2001;37:1703-8.
12. Kunisada T, Miyazaki M, Mihara K, et al. A new human chondrosarcoma cell line (OUMS-27) that maintains chondrocytic differentiation. Int J Cancer 1998;77:854-9.
13. Lebovitz HE, Eisenbarth GS. Hormonal regulation of cartilage growth and metabolism. Vitam Horm 1975;38:575-648.
14. Lee FY, Mankin HJ, Fondren G, et al. Chondrosarcoma of bone: an assessment of outcome. J Bone Joint Surg Am 1999;81:326-38.
15. Mehls O, Himmele R, Homme M, et al. The interaction of glucocorticoids with the growth hormone-insulin-like growth factor axis and its effects on growth plate chondrocytes and bone cells. J Pediatr Endocrinol Metab 2001;14 (suppl 6):1475-82.
16. Miyazaki Y, Tsukazaki T, Hirota Y, et al. Dexamethasone inhibition of TGFβ-induced cell growth and type II collagen mRNA expression through ERK-integrated AP-1 activity in cultured rat articular chondrocytes. Osteoarthritis Cartilage 2000; 8:378-85.
17. Mocetti P, Silvestrini G, Ballanti P, et al. Bcl-2 and Bax expression in cartilage and bone cells after high-dose corticosterone treatment in rats. Tissue Cell 2001;33:1-7.
18. Ovejera AA, Houchens DP. Human tumor xenografts in athymic nude mice as a preclinical screen for anticancer agents. Emin Oncol 1981;8:386-93.
19. Quarto R, Campanile G, Cancedda R, et al. Modulation of commitment, proliferation, and differentiation of chondrogenic cells in defined culture medium. Endocrinology 1997;138:4966-76.
20. Sekiya I, Koopman P, Tsuji K, et al. Dexamethasone enhances SOX9 expression in chondrocytes. J Endocrinol 2001;169:573-9.
21. Silbermann, M. Hormones and cartilage. San Diego: Academic; 1983. p. 327-68.
22. Silvestrini G, Ballanti P, Patacchioli FR, et al. Evaluation of apoptosis and the glucocorticoid receptor in the cartilage growth plate and metaphyseal bone cells of rats after high-dose treatment with corticosterone. Bone 2000;26:33-42.
23. Smink JJ, Koedam JA, Koster JG, et al. Dexamethasone-induced growth inhibition of porcine growth plate chondrocyte is accompanied by changes in levels of IGF axis components. J Endocrinol 2002;175:343-52.
24. Thompson EB, Lippman ME. Mechanism of action of glucocorticoids. Metabolism 1974;23:159-202.
25. Walter EM, Tapas KD, Michael JW. The influence of glucocorticoids on the growth of a human leiomyosarcoma cell line SK-LMS-1. Int J Cancer 1989;44:1034-40.