Treatment of chronic hepatitis C with PEG-interferon alpha-2b and ribavirin: 24 Weeks of therapy are sufficient for HCV genotype 2 and 3;Therapie der chronischen hepatitis C mit PEG-interferon alpha-2b und ribavirin: 24 Wochen behandlung sind ausreichend bei HCV-genotyp 2 und 3
Randomised trial of interferon alpha-2b plus ribavirin for 48 weeks or for 24 weeks versus interferon alpha-2b plus placebo for 48 weeks for treatment of chronic infection with hepatitis C virus
International Hepatitis Interventional Therapy Group (IHIT)
Poynard T, Marcellin P, Lee SS et al. Randomised trial of interferon alpha-2b plus ribavirin for 48 weeks or for 24 weeks versus interferon alpha-2b plus placebo for 48 weeks for treatment of chronic infection with hepatitis C virus. International Hepatitis Interventional Therapy Group (IHIT). Lancet 1998; 352: 1426-1432
Interferon alpha-2b alone or in combination with ribavirin as initial treatment for chronic hepatitis C
Hepatitis Interventional Therapy Group
McHutchison JG, Gordon SC, Schiff ER et al. Interferon alpha-2b alone or in combination with ribavirin as initial treatment for chronic hepatitis C. Hepatitis Interventional Therapy Group. N Engl J Med 1998; 339: 1485-1492
Peginterferon alpha-2b plus ribavirin compared with interferon alpha-2b plus ribavirin for initial treatment of chronic hepatitis C: A randomised trial
Manns MP, McHutchison JG, Gordon SC et al. Peginterferon alpha-2b plus ribavirin compared with interferon alpha-2b plus ribavirin for initial treatment of chronic hepatitis C: a randomised trial. Lancet 2001; 358: 958-965
Peg-Interferon alpha-2a (40KD) (PEGASYS®) in combination with ribavirin (RBV): Efficacy and safety results from a phase III, randomized, double blind, multicentre study examining effect and duration of treatment and RBV dose
Hadziyannis SJ, Cheinquer H, Morgan T et al. Peg-Interferon alpha-2a (40KD) (PEGASYS®) in combination with ribavirin (RBV): efficacy and safety results from a phase III, randomized, double blind, multicentre study examining effect and duration of treatment and RBV dose. J Hepatol 2002; 36: 3
A randomized, double-blind trial comparing pegylated interferon alpha-2b to interferon alpha-2b as initial treatment for chronic hepatitis C
Lindsay KL, Trepo C, Heintges T et al. A randomized, double-blind trial comparing pegylated interferon alpha-2b to interferon alpha-2b as initial treatment for chronic hepatitis C. Hepatology 2001; 34: 395-403
Is an "a la carte" combination interferon alpha-2b plus ribavirin regimen possible for the first line treatment in patients with chronic hepatitis C?
The ALGOVIRC Project Group
Poynard T, McHutchison J, Goodman Z et al. Is an "a la carte" combination interferon alpha-2b plus ribavirin regimen possible for the first line treatment in patients with chronic hepatitis C? The ALGOVIRC Project Group. Hepatology 2000: 31: 211-218
A prospective randomised 24 week trial of peg-interferon alpha-2b plus ribavirin versus standard combination therapy in untreated hepatitis C genotype 2 and 3 patients
Hinrichsen H, Buggisch P, Nasser S et al. A prospective randomised 24 week trial of peg-interferon alpha-2b plus ribavirin versus standard combination therapy in untreated hepatitis C genotype 2 and 3 patients. Hepatology 2002; 36: 311A
Adherence to combination therapy enhances sustained response in genotype-1-infected patients with chronic hepatitis C
McHutchison JG, Manns M, Patel K et al. Adherence to combination therapy enhances sustained response in genotype-1-infected patients with chronic hepatitis C. Gastroenterology 2002; 123: 1061-1069