Lipoxin A4 and aspirin-triggered 15-epi-lipoxin A4 modulate adhesion molecule expression on human leukocytes in whole blood and inhibit neutrophil-endothelial cell adhesion

Advances in Experimental Medicine and Biology

Volumn 507, Issue , 2002, Pages 223-228

  Filep, János G ^a   Zouki, Christine ^a   Petasis, Nicos A ^b   Hachicha, Mohamed ^c   Serhan, Charles N ^c  

^a MAISONNEUVE ROSEMONT HOSPITAL   (Canada)

^b UNIVERSITY OF SOUTHERN CALIFORNIA   (United States)

^c HARVARD MEDICAL SCHOOL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

15 EPILIPOXIN A; 16 PHENOXYLIPOXIN A; ACETYLSALICYLIC ACID; ANTIINFLAMMATORY AGENT; CD11 ANTIGEN; CD18 ANTIGEN; CELL ADHESION MOLECULE; ENDOTHELIAL LEUKOCYTE ADHESION MOLECULE 1; INTERCELLULAR ADHESION MOLECULE 1; L SELECTIN; LIPOXIN A; METHYL LIPOXIN A; UNCLASSIFIED DRUG; HYDROXYICOSATETRAENOIC ACID; LEUKOCYTE ANTIGEN; LIPOXIN;

ANTIGEN EXPRESSION; CELL ADHESION; CONCENTRATION RESPONSE; CONFERENCE PAPER; DRUG EFFECT; ENDOTHELIUM CELL; HUMAN; IC 50; LEUKOCYTE; MONOCYTE; NEUTROPHIL; PRIORITY JOURNAL; PROTEIN EXPRESSION; BLOOD; GENETICS; PHYSIOLOGY; REVIEW;

ANTIGENS, CD; ANTIGENS, CD18; ASPIRIN; CELL ADHESION; CELL ADHESION MOLECULES; HUMANS; HYDROXYEICOSATETRAENOIC ACIDS; L-SELECTIN; LEUKOCYTES; LIPOXINS; NEUTROPHILS;

EID: 0038784260     PISSN: 00652598     EISSN: None     Source Type: Book Series    
DOI: 10.1007/978-1-4615-0193-0_34     Document Type: Conference Paper

References (23)

1. E.C. Butcher, Leukocyte endothelial cell migration: three (or more) steps to specificity and diversity. Cell 67:1033 (1991).
2. T.A. Springer, Traffic signals for lymphocyte recirculation and leukocyte emigration: the multistep paradigm. Cell 76:301 (1994).
3. C.N. Serhan, Lipoxin biosynthesis and its impact in inflammatory and vascular events. Biochim Biophys Acta 1212:1 (1994).
4. C.N. Serhan, Lipoxins and novel aspirin-triggered 15-epi-lipoxins (ATL). Prostaglandins 53:107 (1997).
5. J. Clària, and C.N. Serhan, Aspirin triggers previously undescribed bioactive eicosanoids by human endothelial cell-leukocyte interactions. Proc Natl Acad Sci USA 92:9475 (1995).
6. 4 and N-formyl-L-methionyl-L-leucyl-L-phenylalanine. Clin Sci. 77:195 (1989).
7. 4 on chemotaxis and degranulation by human eosinophils stimulated by platelet-activating factor and N-formyl-L-methionyl-L-leucyl-L-phenylalanine. Allergy 49:230 (1994).
8. 4 stable analogs inhibit leukocyte rolling and adherence in the rat mesenteric microvasculature: Role of P-selectin. Proc Natl Acad Sci USA 94:9967 (1997).
9. 4 inhibit leukotriene-stimulated interactions of human neutrophils and endothelial cells. J Immunol. 156:2264 (1996).
10. 4 modulates transmigration of human neutrophils across intestinal epithelial monolayers. J Clin Invest. 92:75 (1993).
11. 4 during adhesion of platelets and neutrophils in experimental immunecomplex glomerulonephritis. Kidney Int. 47:1295 (1995).
12. 4 stable analogs that block transmigration and adhesion of human neutrophils. Biochemistry 34:14609 (1995).
13. C.B. Clish, J.A. O'Brien, K. Gronert, G.L. Stahl, N.A. Petasis, and C.N. Serhan, Local and systemic delivery of a stable aspirin-triggered lipoxin prevents neutrophil recruitment in vivo. Proc Natl Acad Sci USA 96:8247 (1999).
14. 4 stable analogs are demonstrable in human whole blood: modulation of leukocyte adhesion molecules and inhibition of neutrophil-endothelial interactions. Blood 94:4132 (1999).
15. G.A. Zimmerman, T.M. McIntyre, M. Mehra, and S.M. Prescott, Endothelial cell-associated platelet-activating factor: a novel mechanism for signaling intercellular adhesion. J Cell Biol. 110:529 (1990).
16. G.E. Rainger, A.C. Fisher, and G.B. Nash, Endothelial-borne platelet-activating factor and interleukin-8 rapidly immobilize rolling neutrophils. Amer J Physiol. 41:H114 (1997).
17. T.A. Springer, Folding of the N-terminal, ligand binding region of integrin "-subunits into a $-propeller domain. Proc Natl Acad Sci USA 94:65 (1997).
18. A. McDowall, B. Leitinger, P. Stanley, P.A. Bates, A.M. Radi, and N. Hogg, The 1 domain of integrin leukocyte function-associated antigen-1 is involved in a conformational change leading to high affinity binding to ligand intercellular adhesion molecule-1 (ICAM-1). J.Biol. Chem. 273:27396 (1998).
19. M.P. Stewart, C. Cabanas, and N. Hogg, T cell adhesion to intercellular adhesion molecule-1 (ICAM-1) is controlled by cell spreading and the activation of integrin LFA-1. J Immunol. 156:1810 (1996).
20. C. Zouki, M. Beauchamp, C. Baron, and J.G. Filep, Prevention of in vitro neutrophil adhesion to endothelial cells through shedding of L-selectin by C-reactive protein and peptides derived from C-reactive protein. J Clin Invest. 100:522 (1997).
21. F. Diaz-González, I. González-Alvaro, M. R. Campanero, F. Mollinedo, M. A. del Pozo, C. Muñoz, J.P. Pivel, and F. Sánchez-Madrid, Prevention of in vivo neutrophil-endothelial attachment through shedding of L-selectin by non-steroidal antiinflammatory drugs. J Clin Invest. 95:1756 (1995).
22. B.N. Cronstein, S.C. Kimmel, R.I. Levin, F. Martiniuk, and G. Weissmann, A mechanism for the antiiflammatory effects of corticosteroids: The glucocorticoid receptor regulates leukocyte adhesion to endothelial cells and expression of endothelial-leukocyte adhesion molecule 1 and intercellular adhesion molecule 1. Proc Natl Acad Sci USA 89:9991 (1992).
23. J.G. Filep, A. Delalandre, Y. Payette, and E. Földes-Filep, Glucocorticoid receptor regulates expression of L-selectin and CD11/CD18 on human neutrophils. Circulation 96:295 (1997).