Clinical impact of a 2-week psychotropic medication washout in unipolar depressed inpatients

Journal of Affective Disorders

Volumn 75, Issue 3, 2003, Pages 291-296

  Grunebaum, Michael F ^a   Oquendo, Maria A ^a   Burke, Ainsley K ^a   Ellis, Steven P ^a   Echavarria, Gonzalo ^a   Brodsky, Beth S ^a   Malone, Kevin M ^a   Mann, J John ^a  

^a NEW YORK STATE PSYCHIATRIC INSTITUTE   (United States)

Author keywords

Biological study; Depression; Medication discontinuation; Medication taper; Washout

Indexed keywords

AMFEBUTAMONE; CARBAMAZEPINE; CITALOPRAM; CLOMIPRAMINE; DESIPRAMINE; DOXEPIN; FLUOXETINE; IMIPRAMINE; LITHIUM; MIRTAZAPINE; MONOAMINE OXIDASE INHIBITOR; NEFAZODONE; PAROXETINE; PSYCHOTROPIC AGENT; REBOXETINE; SERTRALINE; VALPROIC ACID; VENLAFAXINE;

ADULT; AGED; ARTICLE; CLINICAL ARTICLE; CLINICAL MEDICINE; DISEASE SEVERITY; DRUG WITHDRAWAL; HOSPITAL ADMISSION; HUMAN; MAJOR DEPRESSION; PRIORITY JOURNAL; TREATMENT OUTCOME;

EID: 0038782247     PISSN: 01650327     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0165-0327(02)00168-4     Document Type: Article

References (16)

1. Baldessarini R.J. Risks and implications of interrupting maintenance psychotropic drug therapy. Psychother. Psychosom. 63:1995;137-141.
2. Beck A.T., Ward C.H., Mendelson M., Mock J., Erbaugh J. An inventory for measuring depression. Arch. Gen. Psychiatry. 4:1961;561-571.
3. Beck A.T., Weissman A., Lester D., Trexler L. The measurement of pessimism: the Hopelessness Scale. J. Consult. Clin. Psychol. 42:1974;861-865.
4. Endicott J., Spitzer R.L., Fleiss J.L., Cohen J. The global assessment scale. A procedure for measuring overall severity of psychiatric disturbance. Arch. Gen. Psychiatry. 33:1976;766-771.
5. Fava G.A. Holding on: depression, sensitization by antidepressant drugs, and the prodigal experts. Psychother. Psychosom. 64:1995;57-61.
6. Frank E., Kupfer D.J., Perel J.M., Cornes C., Mallinger A.G., Thase M.E., McEachran A.B., Grochocinski V.J. Comparison of full-dose vs. half-dose pharmacotherapy in the maintenance treatment of recurrent depression. J. Affect. Disord. 27:1993;139-145.
7. Greenhouse J.B., Stangl D., Kupfer D.J., Prien R.F. Methodologic issues in maintenance therapy clinical trials. Arch. Gen. Psychiatry. 48:1991;313-318.
8. Hamilton M. A rating scale for depression. J. Neurol. Neurosurg. Psychiatry. 23:1960;56-62.
9. Kupfer D.J., Frank E., Perel J.M., Cornes C., Mallinger A.G., Thase M.E., McEachran A.B., Grochocinski V.J. Five-year outcome for maintenance therapies in recurrent depression. Arch. Gen. Psychiatry. 49:1992;769-773.
10. Mann J.J., Waternaux C., Haas G.L., Malone K.M. Toward a clinical model of suicidal behavior in psychiatric patients. Am. J. Psychiatry. 156:1999;181-189.
11. Overall J.E., Gorham D.R. The Brief Psychiatric Rating Scale. Psychol. Rep. 10:1962;799-812.
12. Post R.M., Leverich G.S., Altshuler L., Mikalauskas K. Lithium-discontinuation-induced refractoriness: preliminary observations. Am. J. Psychiatry. 149:1992;1727-1729.
13. Sharma V. Loss of response to antidepressants and subsequent refractoriness: diagnostic issues in a retrospective case series. J. Affect. Disord. 64:2001;99-106.
14. Spitzer R.L., Williams J.B.W., Gibbon M., First M.B. Structured Clinical Interview for DSM-III-R, Version 1.0 (SCID). 1990;American Psychiatric Press, Washington, DC.
15. Suppes T., Baldessarini R.J., Faedda G.L., Tohen M. Risk of recurrence following discontinuation of lithium treatment in bipolar disorder. Arch. Gen. Psychiatry. 48:1991;1082-1088.
16. Suppes T., Baldessarini R.J., Faedda G.L., Tondo L., Tohen M. Discontinuation of maintenance treatment in bipolar disorder: risks and implications. Harvard Rev. Psychiatry. Sep./Oct. 1993;131-144.