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Volumn 28, Issue 2, 2003, Pages 137-141

Oral bioavailability and pharmacokinetics of DRF-4367, a new cox-2 inhibitor in rats

Author keywords

Bioavailability; COX 2 inhibitor; DRF 4367; Pharmacokinetics; Rats

Indexed keywords

2 HYDROXYMETHYL 4 [5 (4 METHOXYPHENYL) 3 TRIFLUOROMETHYL 1H 1 PYRAZOLYL] 1 BENZENESULFONAMIDE; CYCLOOXYGENASE 2 INHIBITOR; DRF 4367; UNCLASSIFIED DRUG;

EID: 0038780872     PISSN: 03787966     EISSN: None     Source Type: Journal    
DOI: 10.1007/BF03190502     Document Type: Article
Times cited : (9)

References (11)
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    • David L DeWitt (1999): COX-2 selective inhibitors: The new super aspirins. Mol Pharmacol; 4: 625-631.
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    • DeWitt, D.L.1
  • 3
    • 0035042458 scopus 로고    scopus 로고
    • Discovery and design of selective cyclooxygenase-2 inhibitors as non-ulcerogenic, anti-inflammaotry drugs with potential utility as anti cancer agents
    • Amit SK, Zhiyang Zhao (2001): Discovery and design of selective cyclooxygenase-2 inhibitors as non-ulcerogenic, anti-inflammaotry drugs with potential utility as anti cancer agents. Current Drug Targets; 2:79-106.
    • (2001) Current Drug Targets , vol.2 , pp. 79-106
    • Amit, S.K.1    Zhao, Z.2
  • 4
    • 0032805977 scopus 로고    scopus 로고
    • Gastrointestinal effects of COX-2 Inhibitors
    • Jackson, L. M.; Hawkey, C. J. (1999): Gastrointestinal effects of COX-2 Inhibitors. Expert Opin. Invest. Drugs, 8, 963-971.
    • (1999) Expert Opin. Invest. Drugs , vol.8 , pp. 963-971
    • Jackson, L.M.1    Hawkey, C.J.2
  • 5
    • 0003187073 scopus 로고    scopus 로고
    • Scrip 2000, 2554, 20.
    • (2000) Scrip , vol.2554 , pp. 20
  • 7
    • 0035246513 scopus 로고    scopus 로고
    • Cyclooxygenase inhibitors - Current status and future prospects
    • For a review, see: Dannhardt, G.; Kiefer, W. (2001): Cyclooxygenase inhibitors - Current status and future prospects. Eur. J. Med. Chem., 36, 109-126.
    • (2001) Eur. J. Med. Chem. , vol.36 , pp. 109-126
    • Dannhardt, G.1    Kiefer, W.2
  • 8
    • 0038642962 scopus 로고    scopus 로고
    • Design synthesis and biological evaluation of 2-substituted benzene sulphonamide containing novel class of 1, 5-diaryl pyrazoles as cyclooxy -genase-2 inhibitors
    • submitted
    • Sunil et al. (2002): Design, Synthesis and Biological Evaluation of 2-Substituted Benzene sulphonamide Containing Novel Class of 1, 5-Diaryl Pyrazoles as Cyclooxy -genase-2 Inhibitors. J. Med. Chem. submitted.
    • (2002) J. Med. Chem.
    • Sunil1
  • 9
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    • Validated HPLC method for determination of DRF-4367, a novel COX-2 inhibitor, in rat plasma
    • in preparation
    • R Mullangi et al.: Validated HPLC method for determination of DRF-4367, a novel COX-2 inhibitor, in rat plasma. J. Pharm. Biomed. App. (in preparation).
    • J. Pharm. Biomed. App.
    • Mullangi, R.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.