Conjugation of low molecular weight poly(ethylene glycol) to biphalin enhances antinociceptive profile

Journal of Pharmaceutical Sciences

Volumn 92, Issue 7, 2003, Pages 1377-1385

  Huber, Jason D ^a   Campos, Chris R ^a   Egleton, Richard D ^a   Witt, Ken ^a   Guo, Lihong ^b   Roberts, Michael J ^b   Bentley, Michael D ^b   Davis, Thomas P ^a  

^a UNIVERSITY OF ARIZONA COLLEGE OF MEDICINE   (United States)

^b Shearwater Corporation   (United States)

Author keywords

Analgesia; Opioid peptide; Tail flick; opioid receptor

Indexed keywords

BIPHALIN; MACROGOL; NALOXONE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANTINOCICEPTION; AREA UNDER THE CURVE; ARTICLE; CONTROLLED STUDY; CYCLIZATION; DERIVATIZATION; DRUG DELIVERY SYSTEM; DRUG EFFICACY; IMMUNOGENICITY; MALE; MATRIX ASSISTED LASER DESORPTION IONIZATION TIME OF FLIGHT MASS SPECTROMETRY; MOUSE; NONHUMAN; PROTEIN DEGRADATION; PROTEIN MODIFICATION; TAIL FLICK TEST;

EID: 0038759641     PISSN: 00223549     EISSN: None     Source Type: Journal    
DOI: 10.1002/jps.10406     Document Type: Article

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