Corneal deposits after the topical use of ofloxacin in two children with vernal keratoconjunctivitis [1]

British Journal of Ophthalmology

Volumn 87, Issue 5, 2003, Pages 646-

  Claerhout, I ^a   Kestelyn, Ph ^a   Meire, Françoise ^a   Remon, J P ^a   Decaestecker, T ^b   Van Bocxlaer, J ^b  

^a GHENT UNIVERSITY HOSPITAL   (Belgium)

^b NONE

Author keywords

[No Author keywords available]

Indexed keywords

ACETONITRILE; CIPROFLOXACIN; CORTICOSTEROID; EMEDASTINE; NORFLOXACIN; OFLOXACIN; PEFLOXACIN; QUINOLONE DERIVATIVE; TETRAMYCIN;

CASE REPORT; CORNEA; CORNEA EROSION; CORNEA ULCER; DISEASE COURSE; DISSOLUTION; DRUG SAFETY; HUMAN; INFLAMMATION; LETTER; MALE; MASS SPECTROMETRY; MEDICAL EXAMINATION; MICROSCOPY; PRESCHOOL CHILD; PRIORITY JOURNAL; SIDE EFFECT; SPECTRUM; UPPER EYELID; VERNAL CONJUNCTIVITIS;

ADMINISTRATION, TOPICAL; ANTI-INFECTIVE AGENTS; CHILD; CHILD, PRESCHOOL; CONJUNCTIVITIS, ALLERGIC; CORNEAL DISEASES; CORNEAL ULCER; HUMANS; MALE; OFLOXACIN;

EID: 0038754787     PISSN: 00071161     EISSN: None     Source Type: Journal    
DOI: 10.1136/bjo.87.5.646     Document Type: Letter

References (8)

1. Pranja NV, George C, Selvaraj S, et al. Bacteriologic and clinical efficacy of ofloxacin 0.3% versus ciprofloxacin 0.3% ophthalmic solutions in the treatment of patients with culture-positive bacterial keratitis. Cornea 2001;20:175-8.
2. Konishi M, Yamada M, Mashima Y. Corneal ulcer associated with deposits of norfloxacin. Am J Ophthalmol 1998;125:258-60.
3. Castillo A, Benitez Del Castillo JM, Toledano N, et al. Deposits of topical norfloxacin in the treatment of bacterial keratitis. Cornea 1997;16:420-3.
4. Eiferman RA, Snyder JP, Nordquist RE. Ciprofloxacin microprecipitates and macroprecipitates in the human corneal epithelium. J Cataract Refract Surg 2001;27:1701-2.
5. Rao SN, Fong Y, Kampmeier J, et al. The effectiveness of a topical antibiotic irrigating solution in a model of staphylococcal keratitis after lamellar keratectomy. Am J Ophthalmol 2000;130:20-4.
6. Essepian JP, Rajpal R, O'Brien TP. Tandem confocal microscopic analysis of ciprofloxacin corneal deposits in viva. Cornea 1995;14:402-7.
7. Firestone BA, Dickason MA, Tran T. Solubility characteristics of three fluoroquinolone ophthalmic solutions in an vitro lear model. Int J Pharm 1998;164:119-28.
8. Kachi S, Hirano K, Takesue Y et al. Unusual corneal deposit after the topical use of cyclosporine as eyedrops. Am J Ophthalmol 2000;130:667-9.