Granulocyte transfusions from G-CSF-stimulated donors for the treatment of severe infections in neutropenic pediatric patients with onco-hematological diseases

Supportive Care in Cancer

Volumn 11, Issue 2, 2003, Pages 101-106

  Cesaro, Simone ^a   Chinello, Pierangelo ^a   De Silvestro, Giustina ^b   Marson, Piero ^b   Picco, Giorgio ^c   Varotto, Stefania ^a   Pittalis, Silvia ^a   Zanesco, Luigi ^a  

^a UNIVERSITY OF PADOVA   (Italy)

^b Transfusion and Apheresis Center   (Italy)

^c Bassano del Grappa Hospital   (Italy)

Author keywords

Cancer; G CSF; Granulocyte transfusions; Neutropenia; Pediatrics

Indexed keywords

AMIKACIN; ANTIBIOTIC AGENT; ANTIFUNGAL AGENT; CEFTAZIDIME; GRANULOCYTE COLONY STIMULATING FACTOR RECEPTOR; PIPERACILLIN; PIPERACILLIN PLUS TAZOBACTAM; TEICOPLANIN; TOBRAMYCIN; VANCOMYCIN; ANTIINFECTIVE AGENT; GRANULOCYTE COLONY STIMULATING FACTOR;

ACUTE LYMPHOBLASTIC LEUKEMIA; ACUTE MYELOBLASTIC LEUKEMIA; ADOLESCENT; APLASTIC ANEMIA; ARTICLE; BONE PAIN; CANCER PATIENT; CHILD; CHILDHOOD CANCER; CLINICAL ARTICLE; DISEASE SEVERITY; DRUG SAFETY; DRUG TOLERABILITY; FATHER; FEMALE; GRANULOCYTE TRANSFUSION; HEMOPHAGOCYTIC LYMPHOHISTIOCYTOSIS; HUMAN; IMMUNE DEFICIENCY; INFANT; INFECTION; LEUKAPHERESIS; LEUKOCYTE; MALAISE; MALE; MOTHER; NEUTROPENIA; NEUTROPHIL; PARESTHESIA; PATIENT SELECTION; PRIORITY JOURNAL; SIBLING; SIDE EFFECT; TREATMENT FAILURE; ACUTE DISEASE; ACUTE LYMPHOCYTIC LEUKEMIA; ALLOTRANSPLANTATION; BLOOD COMPONENT THERAPY; CLINICAL TRIAL; GRANULOCYTE; HISTIOCYTOSIS; LEUKOCYTE COUNT; MYELOID LEUKEMIA; PRESCHOOL CHILD; SUBCUTANEOUS DRUG ADMINISTRATION; TRANSPLANTATION; TREATMENT OUTCOME;

ACUTE DISEASE; ADOLESCENT; ANEMIA, APLASTIC; ANTI-BACTERIAL AGENTS; BLOOD COMPONENT TRANSFUSION; CHILD; CHILD, PRESCHOOL; FEMALE; GRANULOCYTE COLONY-STIMULATING FACTOR; GRANULOCYTES; HISTIOCYTOSIS, NON-LANGERHANS-CELL; HUMANS; INFANT; INFECTION; INJECTIONS, SUBCUTANEOUS; LEUKAPHERESIS; LEUKEMIA, LYMPHOCYTIC, ACUTE; LEUKEMIA, MYELOID; LEUKOCYTE COUNT; MALE; NEUTROPENIA; TRANSPLANTATION, HOMOLOGOUS; TREATMENT OUTCOME;

EID: 0038750634     PISSN: 09414355     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00520-002-0394-8     Document Type: Article

References (25)

1. American Society for Clinical Oncology Ad Hoc Colony - Stimulating Factor Guidelines Expert Panel (1994) American Society recommendations for the use of hematopoietic colony-stimulating factors: evidence-based, clinical practice guidelines. J Clin Oncol 25:247-259
2. Auffermann S, Herzog R, Hebart H, et al (1999) Granulocyte transfusions in neutropenic patients with life threatening infections: prophylactic and therapeutic use. Bone Marrow Transplant 23:S110
3. Bensinger WI, Price TH, Dale DC, et al (1993) The effects of daily recombinant human colony-stimulating factor administration on normal granulocyte donors undergoing leukapheresis. Blood 81:1883-1888
4. Bodey GP, Bukley M, Sathe YS, Freireich EJ (1966) Quantitative relationship between circulating leucocytes and infection in patients with acute leukemia. Ann Intern Med 64:328-340
5. Casper C, Seger R, Burger J, Gmur J (1993) Effective stimulation of donors for granulocyte transfusion with recombinant methionyl granulocyte colony-stimulating factor. Blood 81:2866-2871
6. Dale DC, Liles WC (2000) Return of granulocyte transfusions. Curr Opin Pediatr 12:18-22
7. Elting LS, Rubenstein EB, Rolston KVI, Bodey GP (1997) Outcomes of bacteremia in patients with cancer and neutropenia: observations from two decades of epidemiological and clinical trials. Clin Infect Dis 25:247-259
8. Engels EA, Ellis CA, Supran SE, et al (1999) Early infection in bone marrow transplantation: quantitative study of clinical factors that affect risk. Clin Infect Dis 28:256-264
9. Grigg A, Lusk J, Szer J (1995) CSF stimulated donor granulocyte collections for neutropenic sepsis. Leuk Lymphoma 18:329-334
10. Higby DJ, Burnett D (1980) Granulocyte transfusions: current status. Blood 55:2-8
11. Hughes WT, Armstrong D, Bodey GP, et al (1997) Guidelines for the use of antimicrobial agents in neutropenic patients with unexplained fever. Clin Infect Dis 25:551-573
12. Klastersky J (1995) Prevention and therapy of fungal infections in cancer patients. A review of recently published information. Support Care Cancer 3:393-401
13. Klastersky J (2000) Empirical treatment of sepsis in neutropenic patients. Int J Antimicrob Agents 16:131-133
14. Klein HG, Strauss RG, Shiffer CA (1996) Granulocyte transfusion therapy. Semin Hematol 33:359-368
15. Lee J, Leitman S, Klein H (1995) A controlled comparison of the efficacy of hetastarch and pentastarch in granulocyte collections by centrifugal leukapheresis. Blood 86:4662-4666
16. Peters C, Minkov M, Matthes-Martin S, et al (1999) Leucocyte transfusions from rhG-CSF or prednisolone stimulated donors for treatment of severe infections in immunocompromised neutropenic patients. Br J Haematol 106:689-696
17. Pizzo PA (1993) Management of fever in patients with cancer and treatment-induced neutropenia. N Engl J Med 328:1323-1332
18. Price TH (2000) The use of G-CSF in normal neutrophil donors. Ann Med Interne (Paris) 151:115-122
19. Price TH, Bowden RA, Boeckh M, et al (2000) Phase I/II trial of neutrophil transfusions from donors stimulated with G-CSF and dexamethasone for treatment of patients with infections in hematopoietic stem cell transplantation. Blood 95:3302-3309
20. Rubenstein EB (2000) Colony stimulating factors in patients with fever and neutropenia. Int J Antimicrob Agents 16:117-121
21. Schimpff SC, Scott DA, Wade JC (1994) Infections in cancer patients: some controversial issues. Support Care Cancer 2:94-104
22. Strauss RG. (1993) Therapeutic granulocyte transfusions in 1993. Blood 81:1675-1678
23. Volk E, Domen R, Smith M (1999) An examination of ethical issues raised in the pretreatment of normal volunteer granulocyte donors with granulocyte colony-stimulating factor. Arch Pathol Lab Med 123:508-513
24. Wheeler AP, Bernard GR (1999) Treating patients with severe sepsis. N Engl J Med 340:207-212
25. Wright EF, Robichaud KJ, Pizzo PA, et al (1981) Lethal pulmonary reactions associated with the combined use of amphotericin B and leukocyte transfusions. N Engl J Med 21:1185-1189