Aspirin reversal - An incremental administration of aspirin shortens the bleeding time prolonged by low-dose aspirin

Japanese Journal of Anesthesiology

Volumn 52, Issue 4, 2003, Pages 399-401

  Yokoyama, Takeshi ^a   Yamashita, Koichi ^a   Yamasaki, Fumiyasu ^a   Ueta, Tadashi ^a   Manabe, Masanobu ^a   Nishiyama, Tomoki ^b  

^a KOCHI MEDICAL SCHOOL   (Japan)

^b UNIVERSITY OF TOKYO   (Japan)

Author keywords

Anti platelet drugs; Aspirin; Nonsteroidal anti inflammatory drugs; Prostaglandin I2; Thromboxane A2

Indexed keywords

ACETYLSALICYLIC ACID; ADENOSINE DIPHOSPHATE; COLLAGEN; PROSTACYCLIN; THROMBOXANE A2;

ADULT; ARTICLE; BLEEDING; BLEEDING TIME; CONTROLLED STUDY; HUMAN; HUMAN EXPERIMENT; MALE; PARTIAL THROMBOPLASTIN TIME; PROTHROMBIN TIME; THROMBOCYTE AGGREGATION; THROMBOCYTE COUNT; THROMBOCYTE FUNCTION;

ADULT; ANALGESICS; ASPIRIN; BLEEDING TIME; HUMANS; MALE; PARTIAL THROMBOPLASTIN TIME; PLATELET COUNT; PROTHROMBIN TIME;

EID: 0038745919     PISSN: 00214892     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (3)

1. Marcus AJ. Aspirin and thromboembolism - a possible dilemma. N Engl J Med 1977; 297 (23): 1284-5.
2. Moncada S, Higgas EA, Vane JR. Human arterial and venous tissues generate prostacyclin (prostaglandin X), a potent inhibitor of platelet aggregation. Lancet 1977; 1: 18-20.
3. Cerletti C, Latini R, Del Maschio A, Galleti F, Dejana E, de Gaetano G. Aspirin kinetics and inhibition of platelet thromboxane generation - relevance for a solution of the "aspirin dilemma". Thromb Haemost 1985; 53: 415-8.