Does elevated body mass modify the influence of postmenopausal estrogen replacement on atherosclerosis progression: Results from the estrogen in the prevention of atherosclerosis trial

Atherosclerosis

Volumn 168, Issue 1, 2003, Pages 91-98

  Mack, Wendy J ^a,b   Hameed, Afshan B ^a   Xiang, Min ^a,b   Roy, Subir ^a   Slater, Cristin C ^a   Stanczyk, Frank Z ^a   Lobo, Rogerio A ^c   Liu, Chao Ran ^b   Liu, Ci Hua ^b   Hodis, Howard N ^a,b  

^a UNIVERSITY OF SOUTHERN CALIFORNIA   (United States)

^b UNIVERSITY OF SOUTHERN CALIFORNIA   (United States)

^c CHP 218 ^*  (United States)

Author keywords

Cardiovascular disease; Estrogen replacement therapy; Postmenopausal women; Randomized clinical trial; Subclinical atherosclerosis

Indexed keywords

ANTILIPEMIC AGENT; ESTRADIOL; ESTROGEN;

ADULT; AGED; ARTICLE; ATHEROSCLEROSIS; BODY MASS; CAROTID ARTERY; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DISEASE COURSE; DOUBLE BLIND PROCEDURE; DRUG EFFECT; ESTROGEN THERAPY; FEMALE; HEALTH STATUS; HORMONAL THERAPY; HORMONE DETERMINATION; HUMAN; INTIMA; NORMAL HUMAN; POSTMENOPAUSE; PRIORITY JOURNAL; PROPHYLAXIS; RANDOMIZED CONTROLLED TRIAL; STATISTICAL ANALYSIS; STATISTICAL MODEL;

EID: 0038742057     PISSN: 00219150     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0021-9150(03)00052-2     Document Type: Article

References (20)

1. Kannel W.B., Hjorland M.C., McNamara P.M., Gordon T. Menopause and the risk of cardiovascular disease. The Framingham study. Ann. Intern. Med. 85:1976;447-452.
2. Stampfer M.J., Colditz G.A., Willett W.C. Menopause and heart disease: a review. Ann. N.Y. Acad. Sci. 592:1990;193-203.
3. Sullivan J.M., Vander Zwaag R., Hughes J.P., Maddock V., Kroetz F.W., Ramanathan K.B., et al. Estrogen replacement and coronary artery disease. Effect on survival in postmenopausal women. Arch. Intern. Med. 150:(12):1990;2557-2562.
4. Rodriguez C., Calle E.E., Patel A.V., Tatham L.M., Jacobs E.J., Thun M.J. Effect of body mass on the association between estrogen replacement therapy and mortality among elderly US women. Am. J. Epidemiol. 153:2001;145-152.
5. Risks and benefits of estrogen plus progestin in healthy postmenopausal women: principal results from the Women's Health Initiative randomized controlled trial. JAMA. 288:2002;321-333.
6. Hodis H.N., Mack W.J., Lobo R. Postmenopausal hormone replacement therapy as antiatherosclerotic therapy. Curr. Atherosclerosis Rep. 4:2002;52-58.
7. Hodis H.N., Mack W.J., Lobo R.A., Shoupe D., Sevanian A., Mahrer P.R., et al. Estrogen in the prevention of atherosclerosis: a randomized double-blind, placebo-controlled trial. Ann. Intern. Med. 135:2001;939-953.
8. Beach H.W., Issac O.A., Phillips D.J., Strandness D.S. An ultrasound measurement of superficial femoral artery wall thickness. Ultrasound Med. Biol. 15:1989;723-728.
9. Selzer R.H., Hodis H.N., Kwong-Fu H., Mack W.J., Lee P.L., Liu C.R., et al. Evaluation of computerized edge tracking for quantifying intima-media thickness of the common carotid artery from B-mode ultrasound images. Atherosclerosis. 111:1994;1-11.
10. Selzer R., Mack W., Lee P., Kwong-Fu H., Hodis H.N. Improved common carotid elasticity and intima-media thickness measurements from computer analysis of sequential ultrasound frames. Atherosclerosis. 154:2001;185-193.
11. Hodis H.N., Mack W.J., LaBree L., Selzer R.H., Liu C.L., Liu C.H., et al. The role of carotid arterial intima-media thickness in predicting clinical coronary events. Ann. Intern. Med. 128:1998;262-269.
12. Bots M.L., Hoes A.W., Koudstaal P.J., Hofman A., Grobbee D.E. Common carotid intima-media thickness and risk of stroke and myocardial infarction: the Rotterdam Study. Circulation. 96:1997;1432-1437.
13. O'Leary DH, Polak JF, Kronmal RA, Manolio TA, Burke GL, Wolfson Jr SK, for the Cardiovascular Health Study Collaborative Research Group. Carotid-artery intima media thickness as a risk factor for myocardial infarction and stroke in older adults. N Engl J Med 1999:340:14-22.
14. NHLBI Obesity Education Initiative Expert Panel on the Identification, Evaluation, and Treatment of Overweight and Obesity in Adults. Clinical guidelines on identification, evaluation, and treatment of overweight and obesity in adults-the evidence report. Obes Res 1998; 6(Suppl 2):51S-209S.
15. Calle E.E., Thun M.J., Petrelli J.M., Rodriguez C., Heath C.W. Jr. Body-mass index and mortality in a prospective cohort of US adults. NEJM. 341:1999;1097-1105.
16. Longcope C., Baker S. Androgen and estrogen dynamics: relationships with age, weight, and menopausal status. J. Clin. Endocrinol. Metab. 76:1993;601-604.
17. Barrett-Connor E. Obesity, atherosclerosis and coronary artery disease. Ann. Intern. Med. 103:1985;1010-1019.
18. Longscope C., Baker S. Androgen and estrogen dynamics: relationship with age, weight and menopausal status. J. Clin. Endocrinol. Metab. 76:1993;601-604.
19. Yasui T., Uemura H., Tezuka M., Yamada M., Irahara M., Miura M., et al. Biological effects of hormone replacement therapy in relation to serum estradiol levels. Horm. Res. 56:2001;38-44.
20. Koh K.K., Kang M.H., Jin D.K., Lee S.K., Ahn J.Y., Hwang H.Y., et al. Vascular effects of estrogen in type II diabetic postmenopausal women. JACC. 38:(5):2001;1409-1415.