Synthesis of hydroxyalkyl heterocycles by ring transformation of spiroepoxy lactones with binucleophiles

Synthesis

Volumn , Issue 8, 2003, Pages 1209-1214

  Otto, Andreas ^a   Liebscher, Jürgen ^a  

^a HUMBOLDT UNIVERSITY   (Germany)

Author keywords

1,4 thiazinones; Benzothiopyranones; Diazepinones; Epoxidations; Ring transformation; Thiazepinones; lactams

Indexed keywords

KETONES; OXIDATION; REACTION KINETICS;

SUBSTITUENT PATTERNS;

SYNTHESIS (CHEMICAL);

(2,2 DIMETHYL 1,3 DIOXOLAN 4 YL)HYDROXYMETHYL 2 (2 HYDROXYETHYL) 3 THIOMORPHOLINONE; (2,2 DIMETHYL 1,3 DIOXOLAN 4 YL)HYDROXYMETHYL 2 (3 HYDROXYPROPYL) 3 THIOMORPHOLINONE; 3 HYDROXY 3 (2 HYDROXYETHYL) 1 PHENYL 2 AZETIDINONE; 3 HYDROXY 3 (2 HYDROXYETHYL) 1,3,4,5 TETRAHYDRO 2H 1,5 BENZODIAZEPIN 4 ONE; 3 HYDROXY 3 (2 HYDROXYETHYL) 2,3 DIHYDRO 1,5 BENZOTHIAZEPIN 4(5H) ONE; 3 HYDROXY 3 (2 HYDROXYETHYL) 2,3 DIHYDRO 4H THIOCHROMEN 4 ONE; 6 HYDROXY 6 (2 HYDROXYETHYL) 1,4 THIAZEPAN 5 ONE; ALKYL GROUP; DIAZEPINE DERIVATIVE; EPOXIDE; ETHYLENE OXIDE; HETEROCYCLIC COMPOUND; LACTONE DERIVATIVE; THIAZEPINE DERIVATIVE; UNCLASSIFIED DRUG;

ARTICLE; CHEMICAL REACTION; EPOXIDATION; REACTION ANALYSIS; RING OPENING; SYNTHESIS;

EID: 0038726079     PISSN: 00397881     EISSN: None     Source Type: Journal    
DOI: 10.1055/s-2003-39403     Document Type: Article

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